DNA PLASMID TRANSMISSION IN YEAST IS ASSOCIATED WITH SPECIFIC SUB-NUCLEAR LOCALISATION DURING CELL DIVISION

• Published in: Cell biology international Vol. 26; no. 5; pp. 393 - 405
• Main Authors: Scott-Drew, Suzanna, Wong, C.Michael V.L., Murray, James A.H.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Elsevier Ltd 01.05.2002; Blackwell Publishing Ltd
• Subjects: 2 μ plasmid; 2μ plasmid; Cell Division; Cell Nucleolus; Cell Nucleus - metabolism; Diploidy; DNA, Fungal - physiology; GFP; Haploidy; mitosis; nuclear organisation; Plasmids - physiology; Saccharomyces cerevisiae - genetics; Spindle Apparatus; Telomere; yeast; GFP; nuclear organisation; 2μ plasmid; mitosis; yeast

Circular plasmids in yeast carrying only an origin of DNA replication (ARS) exhibit maternal inheritance bias (MIB) and are poorly transmitted from mother to daughter cell during division. A variety of different sequences that overcome MIB have been described, including centromeric sequences (CEN),...