Detecting benign uterine tumors by autofluorescence lifetime imaging microscopy through adjacent healthy cervical tissues

• Published in: Journal of innovative optical health science Vol. 12; no. 5; pp. 1940006-1 - 1940006-11
• Main Authors: Huang, Maojia, Zhang, Zixiao, Wang, Xinyi, Xie, Yonghui, Fei, Yiyan, Ma, Jiong, Wang, Jing, Chen, Li, Mi, Lan, Wang, Yulan
• Format: Journal Article
• Language: English
• Published: Singapore World Scientific Publishing Company 01.09.2019; World Scientific Publishing Co. Pte., Ltd; World Scientific Publishing
• Subjects: Adenine; Autofluorescence; Benign; benign uterine tumor; Cervix; Chemical compounds; Coenzymes; Diabetes mellitus; Fertility; Fibroids; Flavin-adenine dinucleotide; Fluorescence; fluorescence lifetime imaging; Fluorophores; Hyperthyroidism; Medical imaging; Metabolism; Microscopy; Morphology; NADPH; Nicotinamide; Nicotinamide adenine dinucleotide; Tissues; Tumors; Uterus; metabolism; fluorescence lifetime imaging; benign uterine tumor; Autofluorescence

The endogenous fluorophores such as reduced nicotinamide adenine dinucleotide (phosphate) (NAD(P)H) and flavin adenine dinucleotide (FAD) in cells and tissues can be imaged by fluorescence lifetime imaging microscopy (FLIM) to show the tissue morphology features, as well as the biomolecular changes...