Sinularin induces oxidative stress‐mediated G2/M arrest and apoptosis in oral cancer cells - Chang, Yung‐Ting; Wu, Chang‐Yi; Tang, Jen‐Yang; Huang, Chiung‐Yao; Liaw, Chih‐Chuang; Wu, Shih‐Hsiung; Sheu, Jyh‐Horng; Chang, Hsueh‐Wei (Environmental toxicology, 2017)
Keywords: Acetylcysteine; Acetylcysteine - pharmacology; Adenosine diphosphate; ADP; Annexin V; Antineoplastic Agents - pharmacology; Antineoplastic Agents - toxicity; Antioxidants; Antioxidants - pharmacology; Apoptosis; Apoptosis - drug effects; Cancer; caspases; Caspases - metabolism; Cdc2 protein; Cell cycle; Cell Line, Tumor; Cell morphology; Cell Survival - drug effects; cell viability; Cells; Corals; Cyclin B1; cyclins; Cytology; Cytometry; Diterpenes - pharmacology; Diterpenes - toxicity; drugs; Flow cytometry; G2 Phase Cell Cycle Checkpoints - drug effects; G2/M arrest; Heterocyclic Compounds, 3-Ring - pharmacology; Heterocyclic Compounds, 3-Ring - toxicity; Humans; mouth neoplasms; Mouth Neoplasms - drug therapy; NAD ADP-ribosyltransferase; neoplasm cells; Oral cancer; Oxidative stress; Oxidative Stress - drug effects; Poly(ADP-ribose) polymerase; Poly(ADP-ribose) Polymerases - metabolism; Pretreatment; Proteins; Reactive oxygen species; Reactive Oxygen Species - metabolism; Regulatory proteins; Ribose; sinularin; soft coral; therapeutics; Western blotting; sinularin; apoptosis; soft coral; G2/M arrest; oxidative stress