Accuracy of single molecular biomarkers in saliva for the diagnosis of periodontitis: A systematic review and meta‐analysis

• Published in: Journal of clinical periodontology Vol. 47; no. 1; pp. 2 - 18
• Main Authors: Arias‐Bujanda, Nora, Regueira‐Iglesias, Alba, Balsa‐Castro, Carlos, Nibali, Luigi, Donos, Nikos, Tomás, Inmaculada
• Format: Journal Article
• Language: English
• Published: United States Blackwell Publishing Ltd 01.01.2020
• Subjects: Biomarkers; Diagnosis; diagnostic accuracy; Gelatinase B; Gum disease; Hemoglobin; Humans; Interleukin 1; Interleukin 6; Meta-analysis; molecular biomarkers; Neutrophil collagenase; Periodontitis; predictive values; prevalence; Quality control; Saliva; sensitivity; Sensitivity and Specificity; specificity; Statistical analysis; systematic review; saliva; prevalence; diagnostic accuracy; periodontitis; meta-analysis; specificity; molecular biomarkers; predictive values; sensitivity; systematic review
• ISSN: 0303-6979; 1600-051X; 1600-051X
• DOI: 10.1111/jcpe.13202

Aim To analyse, using a meta‐analytical approach, the diagnostic accuracy of single molecular biomarkers in saliva for the detection of periodontitis in systemically healthy subjects. Materials and Methods Articles on molecular biomarkers in saliva providing a binary contingency table (or sensitivit...