Real‐time identification of liver cancers by using indocyanine green fluorescent imaging

• Published in: Cancer Vol. 115; no. 11; pp. 2491 - 2504
• Main Authors: Ishizawa, Takeaki, Fukushima, Noriyoshi, Shibahara, Junji, Masuda, Koichi, Tamura, Sumihito, Aoki, Taku, Hasegawa, Kiyoshi, Beck, Yoshifumi, Fukayama, Masashi, Kokudo, Norihiro
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.06.2009; Wiley-Blackwell
• Subjects: Adult; Aged; Biological and medical sciences; Carcinoma, Hepatocellular - diagnosis; Colorectal Neoplasms - pathology; Coloring Agents; Computer Systems; diagnosis; Diagnostic Imaging - methods; early hepatocellular carcinoma; Fluorescein Angiography; Fluorescent Dyes; Gastroenterology. Liver. Pancreas. Abdomen; hepatocellular carcinoma; Humans; Indocyanine Green; liver metastasis; Liver Neoplasms - diagnosis; Liver Neoplasms - secondary; liver resection; Liver. Biliary tract. Portal circulation. Exocrine pancreas; Medical sciences; Microscopy, Fluorescence; Middle Aged; Tumors; Digestive system; Liver; Hepatic disease; Hepatocellular carcinoma; Surgical resection; Indocyanine green; Malignant tumor; Real time; Liver cancer; liver resection; Cancerology; Treatment; early hepatocellular carcinoma; Surgery; Digestive diseases; Medical imagery; Early; Diagnosis; Liver metastasis; Cancer

BACKGROUND: We have often encountered difficulties in identifying small liver cancers during surgery. Fluorescent imaging using indocyanine green (ICG) has the potential to detect liver cancers through the visualization of the disordered biliary excretion of ICG in cancer tissues and noncancerous li...