Impact of evidence‐based clinical guidelines on the adoption of postmastectomy radiation in older women

• Published in: Cancer Vol. 117; no. 20; pp. 4595 - 4605
• Main Authors: Shirvani, Shervin M., Pan, I‐Wen, Buchholz, Thomas A., Shih, Ya‐Chen Tina, Hoffman, Karen E., Giordano, Sharon H., Smith, Benjamin D.
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 15.10.2011; Wiley-Blackwell; Wiley Subscription Services, Inc
• Subjects: Age Factors; Aged; Aged, 80 and over; Background radiation; Biological and medical sciences; Breast cancer; breast cancer in older women; Breast Neoplasms - mortality; Breast Neoplasms - pathology; Breast Neoplasms - radiotherapy; Breast Neoplasms - surgery; Cancer; Carcinoma, Ductal, Breast - mortality; Carcinoma, Ductal, Breast - pathology; Carcinoma, Ductal, Breast - radiotherapy; Carcinoma, Ductal, Breast - surgery; clinical practice patterns; Clinical trials; Confidence intervals; Epidemiology; Evidence-Based Medicine; Female; Government programs; Guidelines; Gynecology. Andrology. Obstetrics; Health care; Health Care Surveys; Health risks; Humans; Invasiveness; Kaplan-Meier Estimate; Logistic Models; Lymph nodes; Lymphatic Metastasis; Mammary gland diseases; Mastectomy; Medical research; Medical sciences; Medicare; Multivariate Analysis; Neoplasm Staging; Odds Ratio; Oncology; Patients; postmastectomy radiation; Practice Guidelines as Topic; quality of health care; Radiation; Radiation therapy; Radiotherapy, Adjuvant - statistics & numerical data; Radiotherapy, Adjuvant - utilization; Risk analysis; Risk Assessment; Risk Factors; SEER Program; Statistical analysis; Tumors; United States - epidemiology; utilization of radiation; United States; Human; quality of health care; Breast disease; breast cancer in older women; postmastectomy radiation; Health; utilization of radiation; Evidence-based practice; Breast cancer; Malignant tumor; Evidence-based medicine; clinical practice patterns; Recommendation; Care; Mammary gland diseases; Cancerology; Quality; Adult; Female; Woman; Elderly; Age; Cancer

BACKGROUND: Although postmastectomy radiation therapy (PMRT) improves survival for patients with high‐risk breast cancer, previous literature suggested that it is underused. The impact of recent clinical guidelines on PMRT use is unknown. Accordingly, the authors used the Surveillance, Epidemiology,...