Traumatic brain injury and autophagy: a pilot study about the immunohistochemical expression of LC3B, Beclin 1, p62, and LAMP2A in human autoptic samples

• Published in: Frontiers in molecular neuroscience Vol. 18; p. 1562954
• Main Authors: Livieri, Tommaso, Alfieri, Letizia, Giacomello, Emiliana, Alempijević, Djordje, Petrovic, Tijana, Kolev, Yanko Georgiev, Radaelli, Davide, Neri, Margherita, D’Errico, Stefano
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 28.04.2025
• Subjects: autophagy; Beclin 1; forensic; immunohistochemistry; LC3B; Molecular Neuroscience; traumatic brain injury; autophagy; LC3B; Beclin 1; traumatic brain injury; immunohistochemistry; forensic; p62; LAMP2A

Autophagy is a cellular stress response that has been shown in the literature to be active in cerebral cells after a traumatic brain injury (TBI). The aim of this study is to investigate the potential use of four proteins involved in autophagy (LC3B, Beclin 1, p62, and LAMP2A), as a forensic diagnos...