Discovery, innovation and the cyclical nature of the pharmaceutical business

Unlike many recent articles, which paint the future of the pharmaceutical industry in gloomy colours, this article provides an optimistic outlook. It explores the foundations on which the pharmaceutical industry has based its outstanding successes. Case studies of important drug classes underpin the...

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Published inDrug Discovery Today Vol. 7; no. 10; pp. 563 - 568
Main Authors Schmid, Esther F, Smith, Dennis A
Format Book Review Journal Article
LanguageEnglish
Published Oxford Elsevier Ltd 15.05.2002
Elsevier Science
Subjects
Biological and medical sciences
blockbuster drugs
Drug Design
Drug Industry - methods
Drug Industry - trends
drug sales
General pharmacology
human genome
innovation
Medical sciences
pharmaceutical R&D
Pharmaceutical technology. Pharmaceutical industry
Pharmacology. Drug treatments
Time Factors
innovation
pharmaceutical R&D
blockbuster drugs
Pharmaceutical Science
human genome
Drug Discovery
drug sales
Human
Improvement
Innovation
Psychotropic
Calcium antagonist
Antidepressant agent
Active ingredient
Review
Genome
Pharmaceutical industry
Research and development
Public health
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Abstract Unlike many recent articles, which paint the future of the pharmaceutical industry in gloomy colours, this article provides an optimistic outlook. It explores the foundations on which the pharmaceutical industry has based its outstanding successes. Case studies of important drug classes underpin the arguments made and provide the basis for the authors’ argument that recent technological breakthroughs and the unravelling of the human genome will provide a new wave of high quality targets (substrate) on which the industry can build. The article suggests that in a conducive environment that understands the benefits that pharmaceuticals provide to healthcare, those players who can base their innovation on a sufficient scale and from a large capital base will reshape the industry.
AbstractList Unlike many recent articles, which paint the future of the pharmaceutical industry in gloomy colours, this article provides an optimistic outlook. It explores the foundations on which the pharmaceutical industry has based its outstanding successes. Case studies of important drug classes underpin the arguments made and provide the basis for the authors’ argument that recent technological breakthroughs and the unravelling of the human genome will provide a new wave of high quality targets (substrate) on which the industry can build. The article suggests that in a conducive environment that understands the benefits that pharmaceuticals provide to healthcare, those players who can base their innovation on a sufficient scale and from a large capital base will reshape the industry.
Author Schmid, Esther F
Smith, Dennis A
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Cites_doi 10.3810/pgm.1999.11.780
10.1111/j.1365-2125.1989.tb05435.x
10.1016/S0167-7799(01)01811-X
10.1177/009286150103500105
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Issue 10
Keywords innovation
pharmaceutical R&D
blockbuster drugs
Pharmaceutical Science
human genome
Drug Discovery
drug sales
Human
Improvement
Innovation
Psychotropic
Calcium antagonist
Antidepressant agent
Active ingredient
Review
Genome
Pharmaceutical industry
Research and development
Public health
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SubjectTerms Biological and medical sciences
blockbuster drugs
Drug Design
Drug Industry - methods
Drug Industry - trends
drug sales
General pharmacology
human genome
innovation
Medical sciences
pharmaceutical R&D
Pharmaceutical technology. Pharmaceutical industry
Pharmacology. Drug treatments
Time Factors
Title Discovery, innovation and the cyclical nature of the pharmaceutical business
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https://www.ncbi.nlm.nih.gov/pubmed/12047856
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