Gene expression profiling reveals differential effects of sodium selenite, selenomethionine, and yeast-derived selenium in the mouse

• Published in: Genes & nutrition Vol. 7; no. 2; pp. 155 - 165
• Main Authors: Barger, Jamie L, Kayo, Tsuyoshi, Pugh, Thomas D, Vann, James A, Power, Ronan, Dawson, Karl, Weindruch, Richard, Prolla, Tomas A
• Format: Journal Article
• Language: English
• Published: Germany Springer-Verlag 01.04.2012
• Subjects: cerebral cortex; diet; enzyme activity; gene expression; genes; liver; mice; oxidative stress; Research Paper; selenium; selenomethionine; sodium selenite; weanlings

The essential trace mineral selenium is an important determinant of oxidative stress susceptibility, with several studies showing an inverse relationship between selenium intake and cancer. Because different chemical forms of selenium have been reported to have varying bioactivity, there is a need f...