LDHA-induced histone lactylation mediates the development of osteoarthritis through regulating the transcription activity of TPI1 gene - Xia, Junfeng; Qiao, Zongrui; Hao, Xiao; Zhang, Yin (Autoimmunity (Chur, Switzerland), 2024)
Keywords: Animals; Chondrocytes - metabolism; Disease Models, Animal; Gene Expression Regulation; Glycolysis; histone lactylation; Histones - metabolism; Humans; Lactate Dehydrogenase 5 - metabolism; LDHA; Male; Mice; Mice, Knockout; osteoarthritis; Osteoarthritis - genetics; Osteoarthritis - metabolism; Osteoarthritis - pathology; Promoter Regions, Genetic; TPI1; Transcription, Genetic; LDHA; TPI1; histone lactylation; osteoarthritis; glycolysis