Screening and mechanistic study of natural compounds that enhance T cell anti-tumor effects post-heat treatment - Wang, Zhaoyi; Diao, Zhongqi; Zhang, Yiyan; Liu, Jiangying; Li, Yeshan; Sun, Zijin; Zhen, Huimin; Wang, Haojia; Yang, Siyun; Wang, Tieshan; Ni, Lei (Frontiers in immunology, 2025)
Keywords: adoptive cell therapy; Apoptosis - drug effects; Biological Products - pharmacology; Chinese medicine; Coculture Techniques; enhance immunity; Hot Temperature; Humans; Immunology; Immunotherapy, Adoptive - methods; Jurkat Cells; K562 Cells; Neoplasms - immunology; Neoplasms - therapy; proteomics; T-Lymphocytes - drug effects; T-Lymphocytes - immunology; T-Lymphocytes - metabolism; temperature; untargeted metabolomics; Chinese medicine; untargeted metabolomics; proteomics; RNA-Seq; enhance immunity; temperature; adoptive cell therapy