The value of systemic immune inflammation index, white blood cell to platelet ratio, and homocysteine in predicting the instability of small saccular intracranial aneurysms

• Published in: Scientific reports Vol. 14; no. 1; pp. 24312 - 10
• Main Authors: Zhang, Wanwan, Xiang, Chao, Liu, Boliang, Hou, Fandi, Zheng, Zhanqiang, Chen, Zhongcan, Suo, Lina, Feng, Guang, Gu, Jianjun
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 16.10.2024; Nature Publishing Group; Nature Portfolio
• Subjects: 631/378; 692/308; 692/53; 692/617; Aged; Aneurysm; Aneurysm, Ruptured - blood; Aneurysms; Biomarkers - blood; Blood Platelets - metabolism; Blood Platelets - pathology; Correlation analysis; Female; Homeostasis; Homocysteine; Homocysteine - blood; Humanities and Social Sciences; Humans; Inflammation; Inflammation - blood; Inflammatory marker; Instability; Intracranial Aneurysm - blood; Intracranial Aneurysm - immunology; Intracranial Aneurysm - pathology; Leukocyte Count; Leukocytes; Leukocytes - metabolism; Male; Middle Aged; multidisciplinary; Patients; Platelet Count; Platelets; Prediction models; Retrospective Studies; Risk Factors; Rupture risk; Saccule; Science; Science (multidisciplinary); Small saccular intracranial aneurysms; Systemic immune-inflammatory index; White blood cell and platelet ratio; Inflammatory marker; Small saccular intracranial aneurysms; Systemic immune-inflammatory index; Homocysteine; Rupture risk; White blood cell and platelet ratio

Inflammation has a destructive effect on the homeostasis of the vascular wall, which is involved in the formation, growth, and rupture of human intracranial aneurysms (IAs) disease progression. However, inflammation-related markers have not been well studied in the risk stratification of unruptured...