Effects of bromazepam in frontal theta activity on the performance of a sensorimotor integration task: A quantitative electroencephalography study

Our objective is to verify the modulatory effects of bromazepam on EEG theta absolute power when subjects were submitted to a visuomotor task (i.e., car driver task). Sample was composed of 14 students (9 males and 5 females), right handed, with ages varying between 23 and 42 years (mean = 32.5 ± 9....

Full description

Saved in:

Bibliographic Details
Published in	Neuroscience letters Vol. 451; no. 3; pp. 181 - 184
Main Authors	Fridman, Sander, Machado, Sergio, Cunha, Marlo, Velasques, Bruna, Pompeu, Fernando, Budde, Henning, Cagy, Mauricio, Basile, Luis F., Piedade, Roberto, Ribeiro, Pedro
Format	Journal Article
Language	English
Published	Shannon Elsevier Ireland Ltd 27.02.2009 Elsevier
Subjects	Adult Age Anti-Anxiety Agents - pharmacology Biological and medical sciences Bromazepam Bromazepam - pharmacology Cognition Disorders - chemically induced Cognition Disorders - physiopathology Electroencephalography Female Frontal Lobe - anatomy & histology Frontal Lobe - drug effects Frontal Lobe - physiology Fundamental and applied biological sciences. Psychology Humans Male Movement - drug effects Movement - physiology Neuropsychological Tests Photic Stimulation Psychomotor Performance - drug effects Psychomotor Performance - physiology Sensorimotor integration Space Perception - drug effects Space Perception - physiology Theta Theta Rhythm - drug effects Vertebrates: nervous system and sense organs Visuomotor task Young Adult Visuomotor task Bromazepam Sensorimotor integration Electroencephalography Theta Sensorimotor coordination Electrophysiology
Online Access	Get full text

Cover

Loading…

Abstract	Our objective is to verify the modulatory effects of bromazepam on EEG theta absolute power when subjects were submitted to a visuomotor task (i.e., car driver task). Sample was composed of 14 students (9 males and 5 females), right handed, with ages varying between 23 and 42 years (mean = 32.5 ± 9.5), absence of mental or physical impairments, no psychoactive or psychotropic substance use and no neuromuscular disorders (screened by a clinical examination). The results showed an interaction between condition and electrodes ( p = 0.034) in favor of F8 electrode compared with F7 in both experimental conditions ( t-test; p = 0.001). Additionally, main effects were observed for condition ( p = 0.001), period ( p = 0.001) and electrodes ( p = 0.031) in favor of F4 electrode compared with F3. In conclusion, Br 6 mg of bromazepam may interfere in sensorimotor processes in the task performance in an unpredictable scenario allowing that certain visuospatial factors were predominant. Therefore, the results may reflect that bromazepam effects influence the performance of the involved areas because of the acquisition and integration of sensory stimuli processes until the development of a motor behavior based on the same stimuli.
AbstractList	Our objective is to verify the modulatory effects of bromazepam on EEG theta absolute power when subjects were submitted to a visuomotor task (i.e., car driver task). Sample was composed of 14 students (9 males and 5 females), right handed, with ages varying between 23 and 42 years (mean = 32.5 +/- 9.5), absence of mental or physical impairments, no psychoactive or psychotropic substance use and no neuromuscular disorders (screened by a clinical examination). The results showed an interaction between condition and electrodes (p = 0.034) in favor of F8 electrode compared with F7 in both experimental conditions (t-test; p = 0.001). Additionally, main effects were observed for condition (p = 0.001), period (p = 0.001) and electrodes (p = 0.031) in favor of F4 electrode compared with F3. In conclusion, Br 6 mg of bromazepam may interfere in sensorimotor processes in the task performance in an unpredictable scenario allowing that certain visuospatial factors were predominant. Therefore, the results may reflect that bromazepam effects influence the performance of the involved areas because of the acquisition and integration of sensory stimuli processes until the development of a motor behavior based on the same stimuli. Our objective is to verify the modulatory effects of bromazepam on EEG theta absolute power when subjects were submitted to a visuomotor task (i.e., car driver task). Sample was composed of 14 students (9 males and 5 females), right handed, with ages varying between 23 and 42 years (mean = 32.5 ± 9.5), absence of mental or physical impairments, no psychoactive or psychotropic substance use and no neuromuscular disorders (screened by a clinical examination). The results showed an interaction between condition and electrodes ( p = 0.034) in favor of F8 electrode compared with F7 in both experimental conditions ( t-test; p = 0.001). Additionally, main effects were observed for condition ( p = 0.001), period ( p = 0.001) and electrodes ( p = 0.031) in favor of F4 electrode compared with F3. In conclusion, Br 6 mg of bromazepam may interfere in sensorimotor processes in the task performance in an unpredictable scenario allowing that certain visuospatial factors were predominant. Therefore, the results may reflect that bromazepam effects influence the performance of the involved areas because of the acquisition and integration of sensory stimuli processes until the development of a motor behavior based on the same stimuli. Our objective is to verify the modulatory effects of bromazepam on EEG theta absolute power when subjects were submitted to a visuomotor task (i.e., car driver task). Sample was composed of 14 students (9 males and 5 females), right handed, with ages varying between 23 and 42 years (mean=32.5+/-9.5), absence of mental or physical impairments, no psychoactive or psychotropic substance use and no neuromuscular disorders (screened by a clinical examination). The results showed an interaction between condition and electrodes (p=0.034) in favor of F8 electrode compared with F7 in both experimental conditions (t-test; p=0.001). Additionally, main effects were observed for condition (p=0.001), period (p=0.001) and electrodes (p=0.031) in favor of F4 electrode compared with F3. In conclusion, Br 6mg of bromazepam may interfere in sensorimotor processes in the task performance in an unpredictable scenario allowing that certain visuospatial factors were predominant. Therefore, the results may reflect that bromazepam effects influence the performance of the involved areas because of the acquisition and integration of sensory stimuli processes until the development of a motor behavior based on the same stimuli.Our objective is to verify the modulatory effects of bromazepam on EEG theta absolute power when subjects were submitted to a visuomotor task (i.e., car driver task). Sample was composed of 14 students (9 males and 5 females), right handed, with ages varying between 23 and 42 years (mean=32.5+/-9.5), absence of mental or physical impairments, no psychoactive or psychotropic substance use and no neuromuscular disorders (screened by a clinical examination). The results showed an interaction between condition and electrodes (p=0.034) in favor of F8 electrode compared with F7 in both experimental conditions (t-test; p=0.001). Additionally, main effects were observed for condition (p=0.001), period (p=0.001) and electrodes (p=0.031) in favor of F4 electrode compared with F3. In conclusion, Br 6mg of bromazepam may interfere in sensorimotor processes in the task performance in an unpredictable scenario allowing that certain visuospatial factors were predominant. Therefore, the results may reflect that bromazepam effects influence the performance of the involved areas because of the acquisition and integration of sensory stimuli processes until the development of a motor behavior based on the same stimuli. Our objective is to verify the modulatory effects of bromazepam on EEG theta absolute power when subjects were submitted to a visuomotor task (i.e., car driver task). Sample was composed of 14 students (9 males and 5 females), right handed, with ages varying between 23 and 42 years (mean=32.5+/-9.5), absence of mental or physical impairments, no psychoactive or psychotropic substance use and no neuromuscular disorders (screened by a clinical examination). The results showed an interaction between condition and electrodes (p=0.034) in favor of F8 electrode compared with F7 in both experimental conditions (t-test; p=0.001). Additionally, main effects were observed for condition (p=0.001), period (p=0.001) and electrodes (p=0.031) in favor of F4 electrode compared with F3. In conclusion, Br 6mg of bromazepam may interfere in sensorimotor processes in the task performance in an unpredictable scenario allowing that certain visuospatial factors were predominant. Therefore, the results may reflect that bromazepam effects influence the performance of the involved areas because of the acquisition and integration of sensory stimuli processes until the development of a motor behavior based on the same stimuli.
Author	Fridman, Sander Machado, Sergio Cunha, Marlo Cagy, Mauricio Pompeu, Fernando Velasques, Bruna Budde, Henning Piedade, Roberto Basile, Luis F. Ribeiro, Pedro
Author_xml	– sequence: 1 givenname: Sander surname: Fridman fullname: Fridman, Sander organization: Brain Mapping and Sensory Motor Integration, Institute of Psychiatry of Federal University of Rio de Janeiro (IPUB/UFRJ), Brazil – sequence: 2 givenname: Sergio surname: Machado fullname: Machado, Sergio email: secm80@yahoo.com.br organization: Brain Mapping and Sensory Motor Integration, Institute of Psychiatry of Federal University of Rio de Janeiro (IPUB/UFRJ), Brazil – sequence: 3 givenname: Marlo surname: Cunha fullname: Cunha, Marlo organization: Brain Mapping and Sensory Motor Integration, Institute of Psychiatry of Federal University of Rio de Janeiro (IPUB/UFRJ), Brazil – sequence: 4 givenname: Bruna surname: Velasques fullname: Velasques, Bruna organization: Brain Mapping and Sensory Motor Integration, Institute of Psychiatry of Federal University of Rio de Janeiro (IPUB/UFRJ), Brazil – sequence: 5 givenname: Fernando surname: Pompeu fullname: Pompeu, Fernando organization: School of Physical Education, Bioscience Department (EEFD/UFRJ), Brazil – sequence: 6 givenname: Henning surname: Budde fullname: Budde, Henning organization: Department of Movement and Training Science, Institute of Sport Science, Humboldt University Berlin, Germany – sequence: 7 givenname: Mauricio surname: Cagy fullname: Cagy, Mauricio organization: Division of Epidemiology and Biostatistic, Institute of Health Community, Federal Fluminense University (UFF), Rio de Janeiro, Brazil – sequence: 8 givenname: Luis F. surname: Basile fullname: Basile, Luis F. organization: Division of Neurosurgery, University of São Paulo Medical School, Brazil – sequence: 9 givenname: Roberto surname: Piedade fullname: Piedade, Roberto organization: Brain Mapping and Sensory Motor Integration, Institute of Psychiatry of Federal University of Rio de Janeiro (IPUB/UFRJ), Brazil – sequence: 10 givenname: Pedro surname: Ribeiro fullname: Ribeiro, Pedro organization: Brain Mapping and Sensory Motor Integration, Institute of Psychiatry of Federal University of Rio de Janeiro (IPUB/UFRJ), Brazil
BackLink	http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=21295386$$DView record in Pascal Francis https://www.ncbi.nlm.nih.gov/pubmed/19146918$$D View this record in MEDLINE/PubMed
BookMark	eNqFkc1u1DAURi1URKeFN0DIG2A1wU7iOOkCqarKj1SJDaytO_Y14yGJU9sZaXgMnhiHGUBiUTa-0tU519L3XZCz0Y9IyHPOCs5482ZXjDj3mIqSsbbgZcEEe0RWvJXlWnayPCMrVrF6XXU1OycXMe4YY4KL-gk55x2vm463K_Lj1lrUKVJv6Sb4Ab7jBAN1I7XBjwl6mraYgIJObu_Sgfpx2dAJg_VhgFHjogKNOEYf3OCTD1lP-DVAcgsN8dsVvab3M4zJpbzcI8U-fxo8Zn3aQu8zPG0PNKbZHJ6Sxxb6iM9O85J8eXf7-ebD-u7T-48313drXZdlym8la2O1MEJaa4VlXWug1dghdKZuBEJjULQAGxSZZAw1ClMyrNuNEbq6JK-Pd6fg72eMSQ0uaux7GNHPUbVSCilzhJl89SDZNB3jnWwz-OIEzpsBjZpyIBAO6nfeGXh5AiBq6G3IAbr4hyt52YmqbTJXHzkdfIwB7d9TTC31q5061q-W-hUvVa4_a1f_aPpX4rnJAK7_n_z2KGMOfe8wqKjd0pBxIbeljHcPH_gJ-_3SnA
CODEN	NELED5
CitedBy_id	crossref_primary_10_1016_j_neulet_2011_03_095 crossref_primary_10_1080_02699052_2018_1553309 crossref_primary_10_1590_0004_282X20150140 crossref_primary_10_1016_j_neulet_2009_11_062 crossref_primary_10_1177_1550059414535576
Cites_doi	10.1093/cercor/bhh075 10.1016/S1388-2457(02)00333-4 10.1523/JNEUROSCI.23-11-04726.2003 10.1016/S0165-0173(98)00056-3 10.1038/nrn1849 10.1016/S0893-133X(01)00300-1 10.1016/S0304-3940(01)02535-6 10.1016/0028-3932(89)90071-7 10.1111/j.1469-8986.2006.00388.x 10.1016/S0926-6410(98)00043-3 10.1152/jn.00189.2003 10.33588/rn.4307.2005790 10.1097/00004691-200307000-00004 10.1016/0028-3932(71)90067-4 10.1097/WNR.0b013e3282c48c33 10.1016/j.neulet.2006.08.028 10.1016/j.neulet.2007.08.061 10.1518/hfes.45.4.635.27088 10.1098/rstb.1999.0482 10.1177/155005940603700205 10.1007/BF02244830 10.1016/j.neulet.2008.10.024
ContentType	Journal Article
Copyright	2009 Elsevier Ireland Ltd 2009 INIST-CNRS
Copyright_xml	– notice: 2009 Elsevier Ireland Ltd – notice: 2009 INIST-CNRS
DBID	AAYXX CITATION IQODW CGR CUY CVF ECM EIF NPM 7X8 7TK
DOI	10.1016/j.neulet.2008.12.050
DatabaseName	CrossRef Pascal-Francis Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic Neurosciences Abstracts
DatabaseTitle	CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic Neurosciences Abstracts
DatabaseTitleList	Neurosciences Abstracts MEDLINE - Academic MEDLINE
Database_xml	– sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database
DeliveryMethod	fulltext_linktorsrc
Discipline	Medicine Anatomy & Physiology
EISSN	1872-7972
EndPage	184
ExternalDocumentID	19146918 21295386 10_1016_j_neulet_2008_12_050 S0304394008017503
Genre	Journal Article
GroupedDBID	--- --K --M -~X .55 .GJ .~1 0R~ 123 1B1 1RT 1~. 1~5 29N 4.4 457 4G. 53G 5RE 5VS 7-5 71M 8P~ 9JM AABNK AACTN AADPK AAEDT AAEDW AAIAV AAIKJ AAKOC AALRI AAOAW AAQFI AAQXK AAXLA AAXUO ABCQJ ABFNM ABFRF ABJNI ABLJU ABMAC ABTAH ABXDB ABYKQ ACDAQ ACGFO ACGFS ACIUM ACRLP ADBBV ADEZE ADIYS ADMUD AEBSH AEFWE AEKER AENEX AETEA AFKWA AFTJW AFXIZ AGHFR AGUBO AGWIK AGYEJ AHHHB AHPSJ AIEXJ AIKHN AITUG AJBFU AJOXV ALMA_UNASSIGNED_HOLDINGS AMFUW AMRAJ ASPBG AVWKF AXJTR AZFZN BKOJK BLXMC CS3 DU5 EBS EFJIC EFLBG EJD EO8 EO9 EP2 EP3 F5P FDB FEDTE FGOYB FIRID FNPLU FYGXN G-2 G-Q GBLVA HMQ HVGLF HZ~ IHE J1W KOM M2V M41 MO0 MOBAO MVM N9A O-L O9- OAUVE OZT P-8 P-9 P2P PC. Q38 R2- RIG ROL RPZ SCC SDF SDG SDP SES SEW SNS SPCBC SSN SSZ T5K WH7 WUQ X7M YCJ ZGI ZXP ZY4 ~G- AATTM AAXKI AAYWO AAYXX ABWVN ACRPL ACVFH ADCNI ADNMO AEIPS AEUPX AFJKZ AFPUW AGCQF AGQPQ AGRNS AIGII AIIUN AKBMS AKRWK AKYEP ANKPU APXCP BNPGV CITATION SSH EFKBS IQODW CGR CUY CVF ECM EIF NPM 7X8 7TK
ID	FETCH-LOGICAL-c422t-c4374dfc5d57fff5f098da8ce9ea9d465ea6de58aabe574d00ece5d20e48bd5c3
IEDL.DBID	AIKHN
ISSN	0304-3940
IngestDate	Fri Jul 11 11:04:26 EDT 2025 Thu Jul 10 17:40:52 EDT 2025 Mon Jul 21 06:09:13 EDT 2025 Mon Jul 21 09:13:32 EDT 2025 Thu Apr 24 23:06:09 EDT 2025 Tue Jul 01 04:06:54 EDT 2025 Fri Feb 23 02:27:50 EST 2024
IsPeerReviewed	true
IsScholarly	true
Issue	3
Keywords	Visuomotor task Bromazepam Sensorimotor integration Electroencephalography Theta Sensorimotor coordination Electrophysiology
Language	English
License	https://www.elsevier.com/tdm/userlicense/1.0 CC BY 4.0
LinkModel	DirectLink
MergedId	FETCHMERGED-LOGICAL-c422t-c4374dfc5d57fff5f098da8ce9ea9d465ea6de58aabe574d00ece5d20e48bd5c3
Notes	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 ObjectType-Article-2 ObjectType-Feature-1
PMID	19146918
PQID	66901978
PQPubID	23479
PageCount	4
ParticipantIDs	proquest_miscellaneous_877577304 proquest_miscellaneous_66901978 pubmed_primary_19146918 pascalfrancis_primary_21295386 crossref_primary_10_1016_j_neulet_2008_12_050 crossref_citationtrail_10_1016_j_neulet_2008_12_050 elsevier_sciencedirect_doi_10_1016_j_neulet_2008_12_050
ProviderPackageCode	CITATION AAYXX
PublicationCentury	2000
PublicationDate	2009-02-27
PublicationDateYYYYMMDD	2009-02-27
PublicationDate_xml	– month: 02 year: 2009 text: 2009-02-27 day: 27
PublicationDecade	2000
PublicationPlace	Shannon
PublicationPlace_xml	– name: Shannon – name: Ireland
PublicationTitle	Neuroscience letters
PublicationTitleAlternate	Neurosci Lett
PublicationYear	2009
Publisher	Elsevier Ireland Ltd Elsevier
Publisher_xml	– name: Elsevier Ireland Ltd – name: Elsevier
References	Fonteneau, Davidoff (bib8) 2007; 18 Oldfield (bib19) 1971; 9 Kerick, Hatfield, Allender (bib14) 2007; 78 Caplan, Madsen, Schulze-Bonhage, Aschenbrenner-Scheibe, Newman, Kahana (bib3) 2003; 23 Cunha, Portela, Bastos, Machado, Machado, Velasques, Budde, Basile, Cagy, Piedade, Ribeiro (bib5) 2008; 448 Velasques, Machado, Portella, Silva, Basile, Cagy, Piedade, Ribeiro (bib25) 2007; 426 Klimesch (bib16) 1999; 29 Wilson, Russell (bib27) 2003; 45 Smith, McEvoy, Gevins (bib23) 1999; 7 Dussault, Jouanin, Guezennec (bib6) 2004; 75 Iriarte, Urrestarazu, Valencia, Alegre, Malanda, Viteri, Artieda (bib12) 2003; 20 Mesulam (bib18) 1999; 354 Bagesteiro, Sainburg (bib1) 2003; 90 Saletu, Anderer, Saletu-Zyhlarz, Arnold, Pascual-Marqui (bib21) 2002; 24 Wenderoth, Debaere, Sunaert, van HeckeF P., SwinnenF S.P. (bib26) 2004; 14 Saletu, Anderer, Saletu-Zyhlarz (bib20) 2006; 37 Fink (bib7) 1978; 34 Leeuwen, Verbaten, Koelega, Kenemans, Slangen (bib17) 1992; 106 Jasper (bib13) 1958; 10 Cunha, Machado, Bastos, Ferreira, Basile, Cagy, Piedade, Ribeiro (bib4) 2006; 407 Fridman, Bezerra, Cagy, Basile, Piedade, Ribeiro (bib9) 2006; 43 Szurhaj, Derambure, Labyt, Cassim, Bourriez, Isnard, Guieu, Mauguíere (bib24) 2003; 114 Serrien, Ivry, Swinnen (bib22) 2006; 7 Bastiansen, Berkum, Hagoort (bib2) 2002; 323 Kimura, Katayama, Murohashi (bib15) 2006; 43 Haaland, Harrington (bib11) 1989; 27 Gevins, Smith, McEvoy (bib10) 2002; 26 Iriarte (10.1016/j.neulet.2008.12.050_bib12) 2003; 20 Serrien (10.1016/j.neulet.2008.12.050_bib22) 2006; 7 Jasper (10.1016/j.neulet.2008.12.050_bib13) 1958; 10 Szurhaj (10.1016/j.neulet.2008.12.050_bib24) 2003; 114 Wenderoth (10.1016/j.neulet.2008.12.050_bib26) 2004; 14 Smith (10.1016/j.neulet.2008.12.050_bib23) 1999; 7 Velasques (10.1016/j.neulet.2008.12.050_bib25) 2007; 426 Fonteneau (10.1016/j.neulet.2008.12.050_bib8) 2007; 18 Saletu (10.1016/j.neulet.2008.12.050_bib21) 2002; 24 Caplan (10.1016/j.neulet.2008.12.050_bib3) 2003; 23 Fink (10.1016/j.neulet.2008.12.050_bib7) 1978; 34 Kimura (10.1016/j.neulet.2008.12.050_bib15) 2006; 43 Oldfield (10.1016/j.neulet.2008.12.050_bib19) 1971; 9 Gevins (10.1016/j.neulet.2008.12.050_bib10) 2002; 26 Klimesch (10.1016/j.neulet.2008.12.050_bib16) 1999; 29 Cunha (10.1016/j.neulet.2008.12.050_bib4) 2006; 407 Bagesteiro (10.1016/j.neulet.2008.12.050_bib1) 2003; 90 Saletu (10.1016/j.neulet.2008.12.050_bib20) 2006; 37 Wilson (10.1016/j.neulet.2008.12.050_bib27) 2003; 45 Leeuwen (10.1016/j.neulet.2008.12.050_bib17) 1992; 106 Haaland (10.1016/j.neulet.2008.12.050_bib11) 1989; 27 Bastiansen (10.1016/j.neulet.2008.12.050_bib2) 2002; 323 Kerick (10.1016/j.neulet.2008.12.050_bib14) 2007; 78 Fridman (10.1016/j.neulet.2008.12.050_bib9) 2006; 43 Mesulam (10.1016/j.neulet.2008.12.050_bib18) 1999; 354 Dussault (10.1016/j.neulet.2008.12.050_bib6) 2004; 75 Cunha (10.1016/j.neulet.2008.12.050_bib5) 2008; 448
References_xml	– volume: 323 start-page: 13 year: 2002 end-page: 16 ident: bib2 article-title: Event-related theta power increases in the human EEG during online sentences processing publication-title: Neurosci. Lett. – volume: 43 start-page: 180 year: 2006 end-page: 189 ident: bib15 article-title: Probability-independent and probability-dependent ERPs reflecting visual change detection publication-title: Psychophysiology – volume: 18 start-page: 1323 year: 2007 end-page: 1327 ident: bib8 article-title: Neural correlates of colour categories publication-title: NeuroReport – volume: 24 start-page: 97 year: 2002 end-page: 120 ident: bib21 article-title: Classification and evaluation of the pharmacodynamics of psychotropic drugs by single-lead pharmaco-EEG, EEG mapping and tomography (LORETA) publication-title: Methods Find. Exp. Clin. Pharmacol. – volume: 45 start-page: 635 year: 2003 end-page: 643 ident: bib27 article-title: Real-time assessment mental workload using psychophysiological measures and artificial neural networks publication-title: Hum. Factors – volume: 37 start-page: 66 year: 2006 end-page: 80 ident: bib20 article-title: EEG topography and tomography (LORETA) in the classification and evaluation of the pharmacodynamics of psychotropic drugs publication-title: Clin. EEG Neurosci. – volume: 26 start-page: 27 year: 2002 end-page: 39 ident: bib10 article-title: Tracking the cognitive pharmacodynamics of psychoactive substances with combinations of behavioral and neurophysiological measures publication-title: Neuropsychopharmacology – volume: 29 start-page: 169 year: 1999 end-page: 195 ident: bib16 article-title: EEG alpha and theta oscillations reflect cognitive and memory performance: a review and analysis publication-title: Brain Res. Brain Res. Rev. – volume: 43 start-page: 398 year: 2006 end-page: 402 ident: bib9 article-title: The effects of bromazepam on contingent negative variation and reaction time in a visuomotor task publication-title: Rev. Neurol. – volume: 78 start-page: B153 year: 2007 end-page: 164 ident: bib14 article-title: Event-related cortical dynamics of soldiers during shooting as a function of varied task demand publication-title: Aviat. Space Environ. Med. – volume: 7 start-page: 160 year: 2006 end-page: 166 ident: bib22 article-title: Dynamics of hemispheric specialization and integration in the context of motor control publication-title: Nat. Rev. Neurosci. – volume: 23 start-page: 4726 year: 2003 end-page: 4736 ident: bib3 article-title: Human theta oscillations related to sensorimotor integration and spatial learning publication-title: J. Neurosci. – volume: 20 start-page: 249 year: 2003 end-page: 257 ident: bib12 article-title: Independent component analysis as a tool to eliminate artifacts in EEG: a quantitative study publication-title: J. Clin. Neurophysiol. – volume: 7 start-page: 389 year: 1999 end-page: 404 ident: bib23 article-title: Neurophysiological indices of strategy development and skill acquisition publication-title: Cogn. Brain Res. – volume: 14 start-page: 1153 year: 2004 end-page: 1163 ident: bib26 article-title: Parieto-premotor areas mediate directional interference during bimanual movements publication-title: Cereb. Cortex – volume: 34 start-page: 41 year: 1978 end-page: 56 ident: bib7 article-title: EEG and psychopharmacology publication-title: Electroencephalogr. Clin. Neurophysiol. – volume: 407 start-page: 166 year: 2006 end-page: 170 ident: bib4 article-title: Neuromodulatory effect of bromazepam on motor learning: an electroencephalographic approach publication-title: Neurosci. Lett. – volume: 106 start-page: 555 year: 1992 end-page: 564 ident: bib17 article-title: Effects of bromazepam on single-trial event-related potentials in a visual vigilante task publication-title: Psychopharmacology – volume: 75 start-page: 889 year: 2004 end-page: 897 ident: bib6 article-title: EEG and ECG changes during selected flight sequences publication-title: Aviat. Space Environ. Med. – volume: 114 start-page: 107 year: 2003 end-page: 119 ident: bib24 article-title: Basic mechanisms of central rhythms reactivity to preparation and execution of a voluntary movement: a stereoelectroencephalographic study publication-title: Clin. Neurophysiol. – volume: 426 start-page: 155 year: 2007 end-page: 159 ident: bib25 article-title: Electrophysiological analysis of a sensorimotor integration task publication-title: Neurosci. Lett. – volume: 354 start-page: 1325 year: 1999 end-page: 1346 ident: bib18 article-title: Spatial attention and neglect: parietal, frontal and cingulate contributions to the mental representation and attentional targeting of salient extrapersonal events publication-title: Philos. Trans. R. Soc. Lond. B: Sci. – volume: 90 start-page: 1503 year: 2003 end-page: 1513 ident: bib1 article-title: Nondominant arm advantages in load compensation during rapid elbow joint movements publication-title: J. Neurophysiol. – volume: 27 start-page: 961 year: 1989 end-page: 969 ident: bib11 article-title: Hemispheric control of the initial and corrective components of aiming movements publication-title: Neuropsychologia – volume: 9 start-page: 97 year: 1971 end-page: 113 ident: bib19 article-title: The assessment and analysis of handedness: the Edinburgh inventory publication-title: Neuropsycology – volume: 448 start-page: 33 year: 2008 end-page: 36 ident: bib5 article-title: Responsiveness of sensorimotor cortex during pharmacological intervention with bromazepam publication-title: Neurosci. Lett. – volume: 10 start-page: 371 year: 1958 end-page: 375 ident: bib13 article-title: The ten-twenty electrode system of the International Federation publication-title: Electroencephalogr. Clin. Neurophysiol. – volume: 14 start-page: 1153 year: 2004 ident: 10.1016/j.neulet.2008.12.050_bib26 article-title: Parieto-premotor areas mediate directional interference during bimanual movements publication-title: Cereb. Cortex doi: 10.1093/cercor/bhh075 – volume: 114 start-page: 107 year: 2003 ident: 10.1016/j.neulet.2008.12.050_bib24 article-title: Basic mechanisms of central rhythms reactivity to preparation and execution of a voluntary movement: a stereoelectroencephalographic study publication-title: Clin. Neurophysiol. doi: 10.1016/S1388-2457(02)00333-4 – volume: 23 start-page: 4726 year: 2003 ident: 10.1016/j.neulet.2008.12.050_bib3 article-title: Human theta oscillations related to sensorimotor integration and spatial learning publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.23-11-04726.2003 – volume: 29 start-page: 169 year: 1999 ident: 10.1016/j.neulet.2008.12.050_bib16 article-title: EEG alpha and theta oscillations reflect cognitive and memory performance: a review and analysis publication-title: Brain Res. Brain Res. Rev. doi: 10.1016/S0165-0173(98)00056-3 – volume: 7 start-page: 160 year: 2006 ident: 10.1016/j.neulet.2008.12.050_bib22 article-title: Dynamics of hemispheric specialization and integration in the context of motor control publication-title: Nat. Rev. Neurosci. doi: 10.1038/nrn1849 – volume: 26 start-page: 27 year: 2002 ident: 10.1016/j.neulet.2008.12.050_bib10 article-title: Tracking the cognitive pharmacodynamics of psychoactive substances with combinations of behavioral and neurophysiological measures publication-title: Neuropsychopharmacology doi: 10.1016/S0893-133X(01)00300-1 – volume: 24 start-page: 97 year: 2002 ident: 10.1016/j.neulet.2008.12.050_bib21 article-title: Classification and evaluation of the pharmacodynamics of psychotropic drugs by single-lead pharmaco-EEG, EEG mapping and tomography (LORETA) publication-title: Methods Find. Exp. Clin. Pharmacol. – volume: 323 start-page: 13 year: 2002 ident: 10.1016/j.neulet.2008.12.050_bib2 article-title: Event-related theta power increases in the human EEG during online sentences processing publication-title: Neurosci. Lett. doi: 10.1016/S0304-3940(01)02535-6 – volume: 27 start-page: 961 year: 1989 ident: 10.1016/j.neulet.2008.12.050_bib11 article-title: Hemispheric control of the initial and corrective components of aiming movements publication-title: Neuropsychologia doi: 10.1016/0028-3932(89)90071-7 – volume: 78 start-page: B153 year: 2007 ident: 10.1016/j.neulet.2008.12.050_bib14 article-title: Event-related cortical dynamics of soldiers during shooting as a function of varied task demand publication-title: Aviat. Space Environ. Med. – volume: 43 start-page: 180 year: 2006 ident: 10.1016/j.neulet.2008.12.050_bib15 article-title: Probability-independent and probability-dependent ERPs reflecting visual change detection publication-title: Psychophysiology doi: 10.1111/j.1469-8986.2006.00388.x – volume: 7 start-page: 389 year: 1999 ident: 10.1016/j.neulet.2008.12.050_bib23 article-title: Neurophysiological indices of strategy development and skill acquisition publication-title: Cogn. Brain Res. doi: 10.1016/S0926-6410(98)00043-3 – volume: 90 start-page: 1503 year: 2003 ident: 10.1016/j.neulet.2008.12.050_bib1 article-title: Nondominant arm advantages in load compensation during rapid elbow joint movements publication-title: J. Neurophysiol. doi: 10.1152/jn.00189.2003 – volume: 75 start-page: 889 year: 2004 ident: 10.1016/j.neulet.2008.12.050_bib6 article-title: EEG and ECG changes during selected flight sequences publication-title: Aviat. Space Environ. Med. – volume: 43 start-page: 398 year: 2006 ident: 10.1016/j.neulet.2008.12.050_bib9 article-title: The effects of bromazepam on contingent negative variation and reaction time in a visuomotor task publication-title: Rev. Neurol. doi: 10.33588/rn.4307.2005790 – volume: 20 start-page: 249 year: 2003 ident: 10.1016/j.neulet.2008.12.050_bib12 article-title: Independent component analysis as a tool to eliminate artifacts in EEG: a quantitative study publication-title: J. Clin. Neurophysiol. doi: 10.1097/00004691-200307000-00004 – volume: 9 start-page: 97 year: 1971 ident: 10.1016/j.neulet.2008.12.050_bib19 article-title: The assessment and analysis of handedness: the Edinburgh inventory publication-title: Neuropsycology doi: 10.1016/0028-3932(71)90067-4 – volume: 10 start-page: 371 year: 1958 ident: 10.1016/j.neulet.2008.12.050_bib13 article-title: The ten-twenty electrode system of the International Federation publication-title: Electroencephalogr. Clin. Neurophysiol. – volume: 18 start-page: 1323 year: 2007 ident: 10.1016/j.neulet.2008.12.050_bib8 article-title: Neural correlates of colour categories publication-title: NeuroReport doi: 10.1097/WNR.0b013e3282c48c33 – volume: 407 start-page: 166 year: 2006 ident: 10.1016/j.neulet.2008.12.050_bib4 article-title: Neuromodulatory effect of bromazepam on motor learning: an electroencephalographic approach publication-title: Neurosci. Lett. doi: 10.1016/j.neulet.2006.08.028 – volume: 426 start-page: 155 year: 2007 ident: 10.1016/j.neulet.2008.12.050_bib25 article-title: Electrophysiological analysis of a sensorimotor integration task publication-title: Neurosci. Lett. doi: 10.1016/j.neulet.2007.08.061 – volume: 45 start-page: 635 year: 2003 ident: 10.1016/j.neulet.2008.12.050_bib27 article-title: Real-time assessment mental workload using psychophysiological measures and artificial neural networks publication-title: Hum. Factors doi: 10.1518/hfes.45.4.635.27088 – volume: 354 start-page: 1325 year: 1999 ident: 10.1016/j.neulet.2008.12.050_bib18 article-title: Spatial attention and neglect: parietal, frontal and cingulate contributions to the mental representation and attentional targeting of salient extrapersonal events publication-title: Philos. Trans. R. Soc. Lond. B: Sci. doi: 10.1098/rstb.1999.0482 – volume: 37 start-page: 66 year: 2006 ident: 10.1016/j.neulet.2008.12.050_bib20 article-title: EEG topography and tomography (LORETA) in the classification and evaluation of the pharmacodynamics of psychotropic drugs publication-title: Clin. EEG Neurosci. doi: 10.1177/155005940603700205 – volume: 106 start-page: 555 year: 1992 ident: 10.1016/j.neulet.2008.12.050_bib17 article-title: Effects of bromazepam on single-trial event-related potentials in a visual vigilante task publication-title: Psychopharmacology doi: 10.1007/BF02244830 – volume: 448 start-page: 33 year: 2008 ident: 10.1016/j.neulet.2008.12.050_bib5 article-title: Responsiveness of sensorimotor cortex during pharmacological intervention with bromazepam publication-title: Neurosci. Lett. doi: 10.1016/j.neulet.2008.10.024 – volume: 34 start-page: 41 issue: Suppl. year: 1978 ident: 10.1016/j.neulet.2008.12.050_bib7 article-title: EEG and psychopharmacology publication-title: Electroencephalogr. Clin. Neurophysiol.
SSID	ssj0005154
Score	1.9411988
Snippet	Our objective is to verify the modulatory effects of bromazepam on EEG theta absolute power when subjects were submitted to a visuomotor task (i.e., car driver...
SourceID	proquest pubmed pascalfrancis crossref elsevier
SourceType	Aggregation Database Index Database Enrichment Source Publisher
StartPage	181
SubjectTerms	Adult Age Anti-Anxiety Agents - pharmacology Biological and medical sciences Bromazepam Bromazepam - pharmacology Cognition Disorders - chemically induced Cognition Disorders - physiopathology Electroencephalography Female Frontal Lobe - anatomy & histology Frontal Lobe - drug effects Frontal Lobe - physiology Fundamental and applied biological sciences. Psychology Humans Male Movement - drug effects Movement - physiology Neuropsychological Tests Photic Stimulation Psychomotor Performance - drug effects Psychomotor Performance - physiology Sensorimotor integration Space Perception - drug effects Space Perception - physiology Theta Theta Rhythm - drug effects Vertebrates: nervous system and sense organs Visuomotor task Young Adult
Title	Effects of bromazepam in frontal theta activity on the performance of a sensorimotor integration task: A quantitative electroencephalography study
URI	https://dx.doi.org/10.1016/j.neulet.2008.12.050 https://www.ncbi.nlm.nih.gov/pubmed/19146918 https://www.proquest.com/docview/66901978 https://www.proquest.com/docview/877577304
Volume	451
hasFullText	1
inHoldings	1
isFullTextHit
isPrint
link	http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnR3LbtQwcNSHhJAqBC2P8Fh8QNzC5mE7MbdVRbWA2gtU6i1yYltsYZN0s3uAAx_BFzMTJ11VoqrEJQfLkzgz45mx5wXwJpJVrIVKQ6djE3KLcrDMSxVmmkup0kobRdnIp2dyfs4_XYiLHTgec2EorHKQ_V6m99J6GJkO2Jy2i8X0Czn1-r7eKGTJG7cL-0mqJLL2_uzj5_nZNtIjFr6KFDkBEGDMoOvDvGq7QQT5oEq6F6QE_H9rqINWd4g35xte3G6R9prp5CE8GExKNvOrfgQ7tj6Eo1mNx-nlT_aW9UGe_e35Idw7HXzpR_DHFy7uWONYuWqW-hdqpiVb1MxRUQN8I9qGa80o84EaTLCmphHWblMNCFSzDk_CzYpo3qzYWH5iQbN19_09m7Grja77XDaUrGzou0OIbr_psWI268vcPobzkw9fj-fh0KEhrHiSrPGZZty4ShiROeeEi1RudF5ZZbUyXAqrpbEi17q0AmdGka2sMElkeV4aUaVPYK9uavsMmJbcRdzkZaQctyrNhaoUSp_ERSVaSVEA6UiVohrKl1MXjR_FGKd2WXha-s6acVIgLQMIr6FaX77jjvnZSPDiBhsWqGHugJzc4I_rz6FtoFCryABejwxT4BYmv4yubbPpCklNwfA0HwC7ZUaeZSJDWcwDeOpZbfs3CnWdivPn_73yF3Dfu8goT-sl7K1XG_sKLa11OYHdd7_jybCf_gKrsS1K
linkProvider	Elsevier
linkToHtml	http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnR3LbtQwcFSKBEgIQcsjPFofELewedhJzG1VUS3Q7YVW6i1yYltdYJOw2T3AgY_gi5mxk5ZKVJW45GCNE2dmPDP2vABeR1kdKyHT0KpYh9ygHKyKSoa54lkm01ppSdnI8-Nsdso_nomzLTgYc2EorHKQ_V6mO2k9jEwGbE66xWLymZx6rq83Clnyxt2C2xy3L-3Ot7_-ivOIha8hRS4ABB_z51yQV2M2iB4fUkm3gpR-_2_9dL9TPWLN-nYX19ujTi8dPoQHg0HJpn7Nj2DLNDuwO23wML38wd4wF-Lp7s534M588KTvwm9ftrhnrWXVql2qn6iXlmzRMEslDfCNaBmuFaO8B2ovwdqGRlh3mWhAUxXr8Rzcroji7YqNxScWBK36r-_YlH3fqMZlsqFcZUPXHUJzd67GetnMFbl9DKeH708OZuHQnyGseZKs8ZnmXNtaaJFba4WNZKFVURtplNQ8E0Zl2ohCqcoIhIwiUxuhk8jwotKiTp_AdtM25hkwlXEbcV1UkbTcyLQQspYoexIbVWgjRQGkI1XKeiheTj00vpVjlNqX0tPS99WMkxJpGUB4MavzxTtugM9HgpdXmLBE_XLDzL0r_HHxObQMJDJlFsD-yDAlbmDyyqjGtJu-zKglGJ7lA2DXQBR5LnKUxDyAp57VLv9GoqaTcfH8v1e-D3dnJ_Oj8ujD8acXcM87yyhj6yVsr1cb8wptrnW15_bUHzB3Lg4
openUrl	ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Effects+of+bromazepam+in+frontal+theta+activity+on+the+performance+of+a+sensorimotor+integration+task%3A+a+quantitative+electroencephalography+study&rft.jtitle=Neuroscience+letters&rft.au=Fridman%2C+Sander&rft.au=Machado%2C+Sergio&rft.au=Cunha%2C+Marlo&rft.au=Velasques%2C+Bruna&rft.date=2009-02-27&rft.issn=0304-3940&rft.volume=451&rft.issue=3&rft.spage=181&rft_id=info:doi/10.1016%2Fj.neulet.2008.12.050&rft.externalDBID=NO_FULL_TEXT
thumbnail_l	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0304-3940&client=summon
thumbnail_m	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0304-3940&client=summon
thumbnail_s	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0304-3940&client=summon