Morphological transformations of cells immunopositive for GFAP, TrkA or p75 in the CA1 hippocampal area following transient global ischemia in the rat. A quantitative study

• Published in: Brain research Vol. 987; no. 2; pp. 186 - 193
• Main Authors: Soltys, Z., Janeczko, K., Orzyłowska-Śliwińska, O., Zaremba, M., Januszewski, S., Oderfeld-Nowak, B.
• Format: Journal Article
• Language: English
• Published: London Elsevier B.V 17.10.2003; Amsterdam Elsevier; New York, NY
• Subjects: Animals; Astroglia; Biological and medical sciences; CA1; Carrier Proteins - biosynthesis; Female; Fractal analysis; Glial Fibrillary Acidic Protein - biosynthesis; Hippocampus; Hippocampus - cytology; Hippocampus - metabolism; Ischemia; Ischemic Attack, Transient - metabolism; Ischemic Attack, Transient - pathology; Medical sciences; Membrane Proteins - biosynthesis; Neurology; NGF receptors; p75; Rats; Rats, Wistar; Receptor, Nerve Growth Factor - biosynthesis; Receptor, trkA; TrkA; Vascular diseases and vascular malformations of the nervous system; CA1; Astroglia; TrkA; Development and regeneration; Ischemia; Fractal analysis; Hippocampus; NGF receptors; p75; Rat; Central nervous system; Cardiovascular disease; Cell transformation; Encephalon; Vascular disease; Cerebrovascular disease; Nervous system diseases; p75 receptor; Glial fibrillary acidic protein; Rodentia; Transitory; Cerebral disorder; Vertebrata; Experimental disease; Mammalia; Animal; Central nervous system disease; trkA receptor

Transient global ischemia induces intensive neuronal degeneration in the hippocampal CA1 pyramidal layer, accompanied by reactive transformation of glial cells. Previously, we have shown using the double immunostaining method that the NGF receptors (NGFR) p75 and TrkA are expressed mainly on subpopu...