Recanalization and reperfusion in clinically-relevant porcine model of stroke

• Published in: Frontiers in neuroscience Vol. 19; p. 1572925
• Main Authors: Nowak, Błażej, Holak, Piotr, Małysz-Cymborska, Izabela, Chovsepian, Alexandra, Dening, Yanina, Olszewski, Jarosław, Piecuch, Aleksandra, Jasieniak, Maria, Jasieniak, Jakub, Szterk, Arkadiusz, Sady, Maria, Ferenc, Karolina, Berchtold, Daniel, Jabłoński, Artur, Zabielski, Romuald, Gajewski, Zdzisław, Magnus, Tim, Janowski, Mirosław, Walczak, Piotr, Meisel, Andreas, Pan-Montojo, Francisco, Gołubczyk, Dominika
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 05.06.2025
• Subjects: acute stroke therapy; ischaemic stroke; MRI; Neuroscience; radiology; reperfusion; rtPA; ischaemic stroke; MRI; radiology; rtPA; thrombolysis; acute stroke therapy; reperfusion; stroke

Stroke is a leading cause of death and long-term disability. Pigs have been considered an ideal large animal model in biomedicine; however, the complex vascular anatomy has posed challenges for stroke research. Nonetheless, we have previously overcome these limitations and demonstrated the feasibili...