Long-term outcome of anti-neutrophil cytoplasm antibody-associated glomerulonephritis: evaluation of the international histological classification and other prognostic factors

• Published in: Nephrology, dialysis, transplantation Vol. 30; no. 7; pp. 1185 - 1192
• Main Authors: Tanna, Anisha, Guarino, Laura, Tam, Frederick W K, Rodriquez-Cubillo, Beatriz, Levy, Jeremy B, Cairns, Tom D, Griffith, Megan, Tarzi, Ruth M, Caplin, Benjamin, Salama, Alan D, Cook, Terence, Pusey, Charles D
• Format: Journal Article
• Language: English
• Published: England 01.07.2015
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Antineutrophil Cytoplasmic - blood; Antibodies, Antineutrophil Cytoplasmic - classification; Female; Follow-Up Studies; Glomerular Filtration Rate; Glomerulonephritis - blood; Glomerulonephritis - classification; Glomerulonephritis - diagnosis; Glomerulonephritis - mortality; Humans; International Agencies; Kidney - pathology; Male; Middle Aged; Multivariate Analysis; Prognosis; Survival Rate; Young Adult; glomerulonephritis; ANCA; clinical outcome; vasculitis; renal pathology

Anti-neutrophil cytoplasm antibody (ANCA) associated vasculitis with renal involvement requires treatment with potentially toxic drugs to reduce morbidity and mortality, and there is a major challenge to determine clinical and histological features predictive of renal prognosis. The aim of our study...