Comparison of Fibroblast and Osteoblast Response to Cultivation on Titanium Implants with Different Grain Sizes
The in vitro response of human fibroblast cell line HFL1 and human osteoblast cell line hFOB 1.19 on nanostructured titanium with different grain sizes has been compared in the present study. Used samples of titanium produced by equal channel angular (ECA) pressing have grain sizes of 160 nm, 280 nm...
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Published in | Journal of nanomaterials Vol. 2015; no. 2015; pp. 1 - 9 |
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Main Authors | , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Cairo, Egypt
Hindawi Publishing Corporation
01.01.2015
Hindawi Limited |
Subjects | |
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Abstract | The in vitro response of human fibroblast cell line HFL1 and human osteoblast cell line hFOB 1.19 on nanostructured titanium with different grain sizes has been compared in the present study. Used samples of titanium produced by equal channel angular (ECA) pressing have grain sizes of 160 nm, 280 nm, and 2400 nm with cross- and longitudinal sections. Similar cellular behaviour was observed on all studied biomaterials. There were significant differences related to the initial phase of attachment, but not in proliferation. Furthermore, the results indicate that osteoblasts grow best on material with grain size of 160 nm with a longitudinal section in comparison with other examined materials. Therefore, this material could be recommended for further evaluation with respect to osseointegration in vivo. |
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AbstractList | The in vitro response of human fibroblast cell line HFL1 and human osteoblast cell line hFOB 1.19 on nanostructured titanium with different grain sizes has been compared in the present study. Used samples of titanium produced by equal channel angular (ECA) pressing have grain sizes of 160 nm, 280 nm, and 2400 nm with cross- and longitudinal sections. Similar cellular behaviour was observed on all studied biomaterials. There were significant differences related to the initial phase of attachment, but not in proliferation. Furthermore, the results indicate that osteoblasts grow best on material with grain size of 160 nm with a longitudinal section in comparison with other examined materials. Therefore, this material could be recommended for further evaluation with respect to osseointegration in vivo . |
Author | Moztarzadeh, Amin Kripnerova, Michaela Dobra, Jana Babuska, Vaclav Hrusak, Daniel Lahoda, Jiri Bolek, Lukas Kulda, Vlastimil |
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CitedBy_id | crossref_primary_10_3390_ma11101827 crossref_primary_10_1002_admi_202201725 crossref_primary_10_3390_ijms24043649 crossref_primary_10_1116_1_4958793 crossref_primary_10_1088_2053_1591_ad45be crossref_primary_10_1002_jbm_b_35217 crossref_primary_10_3390_ma12040568 crossref_primary_10_3390_app12136793 crossref_primary_10_1016_j_biomaterials_2019_05_023 crossref_primary_10_3390_ma13030697 |
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ContentType | Journal Article |
Copyright | Copyright © 2015 Vaclav Babuska et al. Copyright © 2015 Vaclav Babuska et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
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Snippet | The in vitro response of human fibroblast cell line HFL1 and human osteoblast cell line hFOB 1.19 on nanostructured titanium with different grain sizes has... |
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SubjectTerms | Biocompatibility Biomedical materials Biotechnology Cytoskeleton Fibroblasts Gene expression Grain size Human Investigations Mechanical properties Medicine Methods Morphology Nanomaterials Proteins Surgical implants Titanium Titanium alloys Topography Transplants & implants |
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Title | Comparison of Fibroblast and Osteoblast Response to Cultivation on Titanium Implants with Different Grain Sizes |
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