Roles of the NLRP3 inflammasome in the pathogenesis of diabetic nephropathy - Qiu, Yuan-ye; Tang, Li-qin (Pharmacological research, 2016)
Keywords: Animals; Diabetic Nephropathies - immunology; Diabetic Nephropathies - pathology; Diabetic Nephropathies - physiopathology; Diabetic nephropathy; Humans; Immunity, Innate; Inflammasomes - analysis; Inflammasomes - immunology; Inflammatory response; Kidney - immunology; Kidney - pathology; Kidney - physiopathology; NLR Family, Pyrin Domain-Containing 3 Protein - analysis; NLR Family, Pyrin Domain-Containing 3 Protein - immunology; NLRP3 inflammasome; Pharmacological target; Regulation; Signal Transduction; Signalling pathway; ESRD; NADPH; Tyr (PubChem CID: 6057); JNK; PTK; Arachidonic acid (PubChem CID: 444899); Inflammatory response; DN; ICAM-1; NLRP3 inflammasome; TNF; LRR; AP-1; NF-κB; ASC; Caspase-1 (PubChem CID: 100953062); Thr (PubChem CID: 6288); GFR; Streptozocin (PubChem CID: 29327); Quercetin (PubChem CID: 5280343); Signalling pathway; NLRP3; TGF-β; Diabetic nephropathy; Allopurinol (PubChem CID: 2094); D-Glucose (PubChem CID: 5793); IL; RAGEs; TGF-β (PubChem CID: 56842206); IL-8 (PubChem CID: 44357137); PKC; IR; MAPK; Uric acid (PubChem CID: 1175); ECM; VCAM-1; AIM2; NOS; Angiotensin II (PubChem CID: 172198); Pharmacological target; ROS; TXNIP; Regulation; NLRs; TLRs; ERK; HG