Cyperotundone promotes chemosensitivity of breast cancer via SRSF1

• Published in: Frontiers in pharmacology Vol. 16; p. 1510161
• Main Authors: Li, Chao, Wang, Lin, Liu, Zhaoyun, Wang, Xinzhao, Sun, Luhao, Song, Xiang, Yu, Zhiyong
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 19.03.2025
• Subjects: breast cancer; cyperotundone; drug resistance; EMT; Pharmacology; SRSF1; breast cancer; cyperotundone; drug resistance; EMT; SRSF1

Breast cancer is among the most common malignancies and the leading cause of cancer-related deaths in women. SRSF1 proteins belong to an important splicing factor (SF) family and bind to different splicing regulatory elements (SREs) to promote or inhibit splicing, such as oncogenic splice-switching...