The oncolytic avian reovirus p17 protein suppresses invadopodia formation via disruption of TKs5 complexes and oncogenic signaling pathways - Hsu, Chao-Yu; Li, Jyun-Yi; Huang, Wei-Ru; Liao, Tsai-Ling; Wen, Hsiao-Wei; Wang, Chi-Young; Lye, Lon-Fye; Nielsen, Brent L.; Liu, Hung-Jen (Frontiers in cellular and infection microbiology, 2025)
Keywords: A549 Cells; Adaptor Proteins, Signal Transducing - genetics; Adaptor Proteins, Signal Transducing - metabolism; Cell Line, Tumor; Cell Movement - drug effects; Cellular and Infection Microbiology; HeLa Cells; Humans; invadopodia formation; oncolytic avian reovirus; Oncolytic Viruses - genetics; Orthoreovirus, Avian - genetics; Orthoreovirus, Avian - metabolism; p17; p53-PTEN-FAK-Src; Podosomes - metabolism; Podosomes - virology; PTEN Phosphohydrolase - genetics; PTEN Phosphohydrolase - metabolism; Signal Transduction; TKs5-Nck1 complex; TKs5-Nck1 complex; oncolytic avian reovirus; p53-PTEN-FAK-Src; invadopodia formation; p17