Dietary biotin supplementation increases proliferation pathways in mice testes without affecting serum follicle-stimulating hormone levels and stem cell factor expression - Salazar-Anzures, Tonatiuh; Pastén-Hidalgo, Karina; Sicilia-Argumedo, Gloria; Riverón-Negrete, Leticia; Hernández-Vázquez, Alain de Jesús; Fernanadez-Mejia, Cristina (Toxicology and applied pharmacology, 2021)
Keywords: AKT; Animals; Biotin; Biotin - toxicity; C-Kit; Cell Cycle Proteins - genetics; Cell Cycle Proteins - metabolism; Cell Proliferation - drug effects; Cyclins; Dietary Supplements - toxicity; ERK; Follicle Stimulating Hormone - blood; Male; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases - metabolism; Phosphorylation; Proliferation; Proto-Oncogene Proteins c-akt - metabolism; Proto-Oncogene Proteins c-kit - genetics; Proto-Oncogene Proteins c-kit - metabolism; Signal Transduction; Sp1 Transcription Factor - genetics; Sp1 Transcription Factor - metabolism; Sp3 Transcription Factor - genetics; Sp3 Transcription Factor - metabolism; Spermatogonia - drug effects; Spermatogonia - metabolism; Spermatogonia - pathology; Stem Cell Factor - metabolism; Testis - drug effects; Testis - metabolism; Testis - pathology; Ccna2; Ccne1; c-kit-Receptor; SE; ERK1; ERK2; p16; Sp1; Sp3; E2F; FSH; pAKTThr308; pAKTSer473; Ccnd3; C-Kit; AKT; Biotin; Proliferation; p21; Cyclins; Cdk4; Tuba1α; Cdk2; SCF; pERK1/2Tyr204; GAPDH; ERK