UPLC–MS/MS method for the simultaneous quantification of three new antiretroviral drugs, dolutegravir, elvitegravir and rilpivirine, and other thirteen antiretroviral agents plus cobicistat and ritonavir boosters in human plasma - Simiele, Marco; Ariaudo, Alessandra; De Nicolò, Amedeo; Favata, Fabio; Ferrante, Martina; Carcieri, Chiara; Bonora, Stefano; Di Perri, Giovanni; D’Avolio, Antonio (Journal of pharmaceutical and biomedical analysis, 2017)
Keywords: Anti-HIV Agents - blood; Anti-HIV Agents - chemistry; Anti-Retroviral Agents - blood; Anti-Retroviral Agents - chemistry; Antiretrovirals; Chromatography, High Pressure Liquid - methods; Cobicistat - blood; Cobicistat - chemistry; HAART; Heterocyclic Compounds, 3-Ring - blood; Heterocyclic Compounds, 3-Ring - chemistry; Humans; Limit of Detection; Liquid chromatography; Protein precipitation; Quinolones - blood; Quinolones - chemistry; Reproducibility of Results; Reverse phase; Rilpivirine - blood; Rilpivirine - chemistry; Ritonavir - blood; Ritonavir - chemistry; Tandem mass spectrometry; Tandem Mass Spectrometry - methods; Tandem mass spectrometry; Antiretrovirals; Liquid chromatography; Reverse phase; Protein precipitation; HAART