Natural products in traditional Chinese medicine for renal fibrosis: a comprehensive review

• Published in: Frontiers in pharmacology Vol. 16; p. 1560567
• Main Authors: Zhao, Qianqian, Jin, Meihua, Zhao, Qiang, Wang, Zhimei, Zhao, Chun, Xue, Xiaocong, Qiao, Xikai, Qu, Peng, Han, Donghe, Tao, Ran
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 16.04.2025
• Subjects: epithelial-mesenchymal transition; inflammation; natural products; oxidative stress; Pharmacology; renal fibrosis; traditional Chinese medicine; natural products; inflammation; TGF-β; traditional Chinese medicine; epithelial-mesenchymal transition; renal fibrosis; oxidative stress
• ISSN: 1663-9812; 1663-9812
• DOI: 10.3389/fphar.2025.1560567

Renal fibrosis represents the terminal pathological manifestation of most chronic kidney diseases, driving progressive loss of renal function. Natural products have emerged as promising therapeutic agents for preventing and ameliorating renal fibrosis due to their multi-target efficacy and favorable...