Duck CD40L as an adjuvant enhances systemic immune responses of avian flavivirus DNA vaccine

• Published in: npj vaccines Vol. 9; no. 1; pp. 135 - 12
• Main Authors: Huang, Juan, Luo, Guiyuan, Wang, Wanfa, Lu, Yuxin, Wang, Mingshu, Liu, Mafeng, Zhu, Dekang, Chen, Shun, Zhao, Xinxin, Yang, Qiao, Wu, Ying, Zhang, Shaqiu, Ou, Xumin, Tian, Bin, Sun, Di, He, Yu, Wu, Zhen, Cheng, Anchun, Jia, Renyong
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.08.2024; Nature Publishing Group; Nature Portfolio
• Subjects: 631/250/24/590; 631/250/590/2291; Adjuvants; Aquatic birds; Biomedical and Life Sciences; Biomedicine; Deoxyribonucleic acid; DNA; Immunization; Immunogenicity; Infectious Diseases; Lymphocytes; Medical Microbiology; Pathogens; Public Health; Strategic management; Vaccine; Vaccines; Virology; Zoonoses

Under the dual pressure of emerging zoonoses and the difficulty in eliminating conventional zoonoses, the strategic management of bird diseases through vaccination represents a highly efficacious approach to disrupting the transmission of zoonotic pathogens to humans. Immunization with a DNA vaccine...