Ribosomal Chamber Music: Toward an Understanding of IRES Mechanisms

Internal initiation is a 5′-end-independent mode of translation initiation engaged by many virus- and putatively some cell-encoded templates. Internal initiation is facilitated by specific RNA tertiary folds, called internal ribosomal entry sites (IRESs), in the 5′ untranslated region (UTR) of the r...

Full description

Saved in:
Bibliographic Details
Published inTrends in biochemical sciences (Amsterdam. Regular ed.) Vol. 42; no. 8; pp. 655 - 668
Main Authors Yamamoto, Hiroshi, Unbehaun, Anett, Spahn, Christian M.T.
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.08.2017
Subjects
Online AccessGet full text

Cover

Loading…
Abstract Internal initiation is a 5′-end-independent mode of translation initiation engaged by many virus- and putatively some cell-encoded templates. Internal initiation is facilitated by specific RNA tertiary folds, called internal ribosomal entry sites (IRESs), in the 5′ untranslated region (UTR) of the respective transcripts. In this review we discuss recent structural insight into how established IRESs first capture and then manipulate the eukaryotic translation machinery through non-canonical interactions and by guiding the intrinsic conformational flexibility of the eukaryotic ribosome. Because IRESs operate with reduced complexity and constitute minimal systems of initiation, comparison with canonical initiation may allow common mechanistic principles of the ribosome to be delineated. IRESs are cis-acting RNA elements that enable the assembly of elongation competent ribosomes in a cap- and end-independent manner. Their structural diversity is reflected by a varying requirement of initiation factors and distinct modus operandi. IRES-driven translation initiation is established for many positive strand RNA virus families. These IRESs have been subjected to extensive biochemical studies. IRES-mediated protein synthesis has also been claimed for some cellular mRNAs, but further experiments will be necessary to sustain and proof this interesting question. Established viral IRESs operate by structural and functional modularity. Recent high resolution structures and biochemical experiments show us how hepatitis C virus-like and type IV intergenic region IRESs become actively engaged to recruit ribosomes and to govern downstream initiation events. Similarly to eukaryotic translation initiation factors, IRES RNAs tune the conformational energy landscape of the ribosome; for example, to induce opening of the mRNA entry channel by rearrangements of the ribosomal 40S subunit head.
AbstractList Internal initiation is a 5'-end-independent mode of translation initiation engaged by many virus- and putatively some cell-encoded templates. Internal initiation is facilitated by specific RNA tertiary folds, called internal ribosomal entry sites (IRESs), in the 5' untranslated region (UTR) of the respective transcripts. In this review we discuss recent structural insight into how established IRESs first capture and then manipulate the eukaryotic translation machinery through non-canonical interactions and by guiding the intrinsic conformational flexibility of the eukaryotic ribosome. Because IRESs operate with reduced complexity and constitute minimal systems of initiation, comparison with canonical initiation may allow common mechanistic principles of the ribosome to be delineated.
Internal initiation is a 5′-end-independent mode of translation initiation engaged by many virus- and putatively some cell-encoded templates. Internal initiation is facilitated by specific RNA tertiary folds, called internal ribosomal entry sites (IRESs), in the 5′ untranslated region (UTR) of the respective transcripts. In this review we discuss recent structural insight into how established IRESs first capture and then manipulate the eukaryotic translation machinery through non-canonical interactions and by guiding the intrinsic conformational flexibility of the eukaryotic ribosome. Because IRESs operate with reduced complexity and constitute minimal systems of initiation, comparison with canonical initiation may allow common mechanistic principles of the ribosome to be delineated. IRESs are cis-acting RNA elements that enable the assembly of elongation competent ribosomes in a cap- and end-independent manner. Their structural diversity is reflected by a varying requirement of initiation factors and distinct modus operandi. IRES-driven translation initiation is established for many positive strand RNA virus families. These IRESs have been subjected to extensive biochemical studies. IRES-mediated protein synthesis has also been claimed for some cellular mRNAs, but further experiments will be necessary to sustain and proof this interesting question. Established viral IRESs operate by structural and functional modularity. Recent high resolution structures and biochemical experiments show us how hepatitis C virus-like and type IV intergenic region IRESs become actively engaged to recruit ribosomes and to govern downstream initiation events. Similarly to eukaryotic translation initiation factors, IRES RNAs tune the conformational energy landscape of the ribosome; for example, to induce opening of the mRNA entry channel by rearrangements of the ribosomal 40S subunit head.
Author Unbehaun, Anett
Spahn, Christian M.T.
Yamamoto, Hiroshi
Author_xml – sequence: 1
  givenname: Hiroshi
  surname: Yamamoto
  fullname: Yamamoto, Hiroshi
  organization: Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institut für Medizinische Physik und Biophysik, Charitéplatz 1, 10117 Berlin, Germany
– sequence: 2
  givenname: Anett
  surname: Unbehaun
  fullname: Unbehaun, Anett
  organization: Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institut für Medizinische Physik und Biophysik, Charitéplatz 1, 10117 Berlin, Germany
– sequence: 3
  givenname: Christian M.T.
  surname: Spahn
  fullname: Spahn, Christian M.T.
  email: christian.spahn@charite.de
  organization: Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institut für Medizinische Physik und Biophysik, Charitéplatz 1, 10117 Berlin, Germany
BackLink https://www.ncbi.nlm.nih.gov/pubmed/28684008$$D View this record in MEDLINE/PubMed
BookMark eNp9kL1OwzAURi1UREvhBRhQRpaEaydxHMSCKn4qgZAKzJZj31BXjQ12CuLtSVVgZLrL-Y50zyEZOe-QkBMKGQXKz1dZb5uYMaBVBjwDYHtkQnPO0iJnfEQmUHORAkAxJocxrgBoWVXlARkzwUUBICZktrCNj75T62S2VF2DIXnYRKsvkmf_qYJJlEtenMEQe-WMda-Jb5P54vopeUC9VM7GLh6R_VatIx7_3Cl5ubl-nt2l94-389nVfaoLxvq0aLhAoTVH1lRQalEXLS3rnFJUVYOs1S3PNVKAsiyaVoAQrMqpMZqbuuV1PiVnO-9b8O8bjL3sbNS4XiuHfhMlrWmVc1rmbEDZDtXBxxiwlW_Bdip8SQpyG0-u5Dae3MaTwOUQbxid_vg3TYfmb_JbawAudwAOX35YDDJqi06jsQF1L423__m_AbH_gMA
CitedBy_id crossref_primary_10_3390_v13060952
crossref_primary_10_1016_j_virol_2019_11_010
crossref_primary_10_1016_j_tibs_2018_04_011
crossref_primary_10_1007_s12268_019_1059_1
crossref_primary_10_1002_wrna_1645
crossref_primary_10_3390_ijms232415497
crossref_primary_10_1128_mbio_00358_23
crossref_primary_10_3390_ijms21072328
crossref_primary_10_3390_genes9090462
crossref_primary_10_1093_nar_gkaa728
crossref_primary_10_1261_rna_068585_118
crossref_primary_10_1038_s41418_018_0244_y
crossref_primary_10_1016_j_celrep_2018_11_040
crossref_primary_10_1093_nar_gkx991
crossref_primary_10_1093_nar_gkad763
crossref_primary_10_1093_nar_gkaa453
crossref_primary_10_1002_2211_5463_13400
crossref_primary_10_15252_embr_202255218
crossref_primary_10_1016_j_gpb_2020_03_001
crossref_primary_10_1080_15476286_2020_1766179
crossref_primary_10_1093_nar_gkad569
crossref_primary_10_1186_s12964_019_0496_2
crossref_primary_10_7554_eLife_54575
crossref_primary_10_1074_jbc_H118_005799
crossref_primary_10_1016_j_tips_2021_06_001
crossref_primary_10_1261_rna_065466_117
crossref_primary_10_1134_S0006297921090042
crossref_primary_10_1261_rna_079462_122
crossref_primary_10_1080_02648725_2018_1471567
crossref_primary_10_3390_ijms20184464
crossref_primary_10_15252_embj_2020104763
crossref_primary_10_7554_eLife_34062
crossref_primary_10_3389_fmolb_2020_00220
crossref_primary_10_3390_pathogens8010028
crossref_primary_10_3390_ijms25095031
crossref_primary_10_1016_j_celrep_2018_07_074
crossref_primary_10_3389_fmicb_2017_02629
crossref_primary_10_1089_ars_2023_0478
crossref_primary_10_1080_15476286_2019_1652524
crossref_primary_10_5483_BMBRep_2022_55_3_188
crossref_primary_10_1002_jcb_27670
crossref_primary_10_31857_S0320972521090049
crossref_primary_10_3390_ijms21113868
crossref_primary_10_7717_peerj_10718
crossref_primary_10_1371_journal_pone_0213758
crossref_primary_10_3390_ijms20164043
crossref_primary_10_1007_s11033_018_4351_0
crossref_primary_10_1093_nar_gkac697
crossref_primary_10_1016_j_jiec_2019_06_042
crossref_primary_10_1016_j_xcrm_2024_101555
crossref_primary_10_15252_embj_2019102226
crossref_primary_10_1098_rsob_180155
crossref_primary_10_1093_nar_gkaa519
crossref_primary_10_1002_wrna_1473
crossref_primary_10_1128_MMBR_00067_17
crossref_primary_10_26508_lsa_201800131
Cites_doi 10.1128/JVI.76.10.5024-5033.2002
10.1038/nsmb.2859
10.1101/gad.14.16.2028
10.1038/sj.emboj.7601549
10.1126/science.1133281
10.1038/nature14267
10.1016/j.cell.2011.10.002
10.1073/pnas.241286698
10.1126/science.7536344
10.1016/j.ymeth.2015.06.023
10.1016/j.virusres.2012.10.006
10.1016/j.molcel.2005.09.008
10.1128/MCB.16.12.6859
10.1128/JVI.74.1.272-280.2000
10.1074/jbc.R110.150532
10.1002/embj.201386124
10.1038/srep37319
10.1073/pnas.1111303109
10.1016/j.molcel.2011.07.040
10.1016/S0076-6879(07)30013-X
10.1128/JVI.05862-11
10.1038/35002118
10.1016/j.molcel.2014.12.016
10.1111/febs.12890
10.1073/pnas.0900153106
10.1073/pnas.1413472111
10.1038/nsb1004
10.1016/j.chom.2009.11.004
10.1146/annurev-biochem-060713-035802
10.1128/MCB.25.23.10556-10565.2005
10.1074/jbc.M610887200
10.1101/gad.12.1.67
10.1016/j.tcb.2015.02.001
10.1016/j.cell.2014.04.015
10.1038/334320a0
10.1146/annurev-virology-100114-055014
10.1016/j.cell.2014.10.041
10.1038/nsmb1177
10.1101/gad.1957510
10.1016/j.str.2011.08.002
10.1016/j.cell.2004.08.001
10.1016/j.virol.2015.02.016
10.7554/eLife.21198
10.1016/j.cell.2015.03.052
10.1016/j.molcel.2015.06.033
10.1126/science.1255030
10.1128/JVI.73.4.3467-3472.1999
10.1017/S1355838202022057
10.1016/0092-8674(78)90039-9
10.1038/nsmb.3280
10.1073/pnas.010426997
10.1126/science.aad4939
10.1016/j.virusres.2008.06.004
10.1261/rna.2342306
10.1073/pnas.1414678111
10.1016/j.virusres.2015.01.012
10.1128/JVI.00896-12
10.1038/nature12658
10.1093/nar/gkg336
10.1038/280082a0
10.1016/j.molcel.2007.03.018
10.1016/0092-8674(92)90211-T
10.1101/gad.282418.116
10.1093/nar/gku877
10.1128/MCB.23.2.687-698.2003
10.7554/eLife.13567
10.1016/j.cell.2011.03.028
10.1093/nar/gkr045
10.1016/j.molcel.2009.04.015
10.1016/S0022-2836(02)01099-9
10.1101/cshperspect.a011569
10.1128/MCB.16.12.6870
10.1101/gad.1020902
10.1091/mbc.e06-06-0478
10.1038/nature14891
10.1038/emboj.2011.146
10.1073/pnas.1320387110
10.1093/nar/gkr114
10.15252/embj.201592469
10.1017/S1355838201001790
10.3109/10409238.2014.887051
10.1038/nsmb.1445
10.1128/MCB.00879-12
10.1038/nature18647
10.7554/eLife.13429
10.1073/pnas.1406335111
10.1016/j.str.2014.06.003
10.1016/j.molcel.2016.03.020
10.1016/j.cell.2015.10.012
10.1038/nature09547
10.1073/pnas.95.19.11089
10.1038/nsmb.1572
10.1038/nature14010
10.1038/nature18954
10.1134/S0006297913010069
10.1073/pnas.1421328111
10.1038/nsmb1351
10.1016/j.virol.2007.03.013
10.1128/JVI.02006-09
10.1111/febs.13756
10.1038/nature11055
10.15252/msb.20155865
10.1017/S1355838201001741
10.1101/gad.1832209
10.1038/emboj.2008.49
10.1038/ncomms8646
10.1093/nar/gku720
10.7554/eLife.14874
10.1038/ncomms2611
10.1128/JVI.62.8.2636-2643.1988
10.1016/S0076-6879(07)30016-5
10.1073/pnas.71.4.1342
10.1038/nchembio.217
10.1126/science.1058409
10.1016/j.biochi.2015.12.004
10.1038/nsmb.2465
10.1038/srep24243
10.1128/JVI.72.6.4775-4782.1998
10.1128/JVI.02403-06
10.1093/emboj/20.15.4233
10.1016/S0092-8674(00)00055-6
ContentType Journal Article
Copyright 2017 Elsevier Ltd
Copyright © 2017 Elsevier Ltd. All rights reserved.
Copyright_xml – notice: 2017 Elsevier Ltd
– notice: Copyright © 2017 Elsevier Ltd. All rights reserved.
DBID CGR
CUY
CVF
ECM
EIF
NPM
AAYXX
CITATION
7X8
DOI 10.1016/j.tibs.2017.06.002
DatabaseName Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
CrossRef
MEDLINE - Academic
DatabaseTitle MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
CrossRef
MEDLINE - Academic
DatabaseTitleList MEDLINE

MEDLINE - Academic
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
DeliveryMethod fulltext_linktorsrc
Discipline Biology
EISSN 1362-4326
EndPage 668
ExternalDocumentID 10_1016_j_tibs_2017_06_002
28684008
S0968000417301081
Genre Journal Article
Review
GroupedDBID ---
--K
--M
-DZ
-~X
.55
.GJ
.~1
0R~
123
1B1
1CY
1RT
1~.
1~5
29Q
3EH
3O-
4.4
457
4G.
53G
5VS
7-5
71M
85S
8P~
9JM
9M8
AABNK
AACTN
AAEDT
AAEDW
AAIAV
AAIKJ
AAKOC
AALRI
AAOAW
AAQFI
AAXUO
ABFNM
ABFRF
ABGSF
ABJNI
ABLJU
ABMAC
ABOCM
ABUDA
ABXDB
ABYKQ
ACDAQ
ACGFO
ACGFS
ACGOD
ACKIV
ACNCT
ACPRK
ACRLP
ADBBV
ADEZE
ADUVX
AEBSH
AEFWE
AEHWI
AEKER
AENEX
AFKWA
AFRAH
AFTJW
AFXIZ
AGHFR
AGRDE
AGUBO
AGYEJ
AHHHB
AHPSJ
AIEXJ
AIKHN
AITUG
AJBFU
AJOXV
ALMA_UNASSIGNED_HOLDINGS
AMFUW
AMRAJ
ASPBG
AVWKF
AXJTR
AZFZN
BKOJK
BLXMC
CS3
D0L
DOVZS
DU5
EBS
EFJIC
EFLBG
EJD
EO8
EO9
EP2
EP3
F5P
FA8
FDB
FEDTE
FGOYB
FIRID
FNPLU
FYGXN
G-2
G-Q
GBLVA
HLW
HVGLF
HZ~
H~9
IH2
IHE
J1W
KOM
LX3
M41
MO0
MVM
N9A
O-L
O9-
OAUVE
OHT
OZT
P-8
P-9
P2P
PC.
PQQKQ
Q38
R2-
RIG
RNS
ROL
RPZ
RXW
SBG
SCC
SDF
SDG
SDP
SES
SEW
SPCBC
SSU
SSZ
T5K
TAE
UQL
WUQ
X7M
XFK
XPP
Y6R
ZCA
ZMT
~G-
AAHBH
AAMRU
AAXKI
ADVLN
AKRWK
CGR
CUY
CVF
ECM
EIF
NPM
AAYXX
CITATION
7X8
ID FETCH-LOGICAL-c422t-4b68e8cc6e2b705c894f159311ea7be2fcf63ce100554bf80882731ddc6d9f693
IEDL.DBID AIKHN
ISSN 0968-0004
IngestDate Fri Oct 25 21:41:37 EDT 2024
Thu Sep 26 17:14:48 EDT 2024
Sat Sep 28 08:49:43 EDT 2024
Fri Feb 23 02:16:38 EST 2024
IsPeerReviewed true
IsScholarly true
Issue 8
Keywords ribosome
internal ribosome entry site
eukaryotic translation initiation
Language English
License Copyright © 2017 Elsevier Ltd. All rights reserved.
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c422t-4b68e8cc6e2b705c894f159311ea7be2fcf63ce100554bf80882731ddc6d9f693
Notes ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
PMID 28684008
PQID 1917361532
PQPubID 23479
PageCount 14
ParticipantIDs proquest_miscellaneous_1917361532
crossref_primary_10_1016_j_tibs_2017_06_002
pubmed_primary_28684008
elsevier_sciencedirect_doi_10_1016_j_tibs_2017_06_002
PublicationCentury 2000
PublicationDate August 2017
2017-08-00
20170801
PublicationDateYYYYMMDD 2017-08-01
PublicationDate_xml – month: 08
  year: 2017
  text: August 2017
PublicationDecade 2010
PublicationPlace England
PublicationPlace_xml – name: England
PublicationTitle Trends in biochemical sciences (Amsterdam. Regular ed.)
PublicationTitleAlternate Trends Biochem Sci
PublicationYear 2017
Publisher Elsevier Ltd
Publisher_xml – name: Elsevier Ltd
References Xue (bib0575) 2015; 517
Lukavsky (bib0220) 2003; 10
Yu (bib0530) 2011; 39
Pfingsten (bib0385) 2006; 314
Llacer (bib0335) 2015; 59
de Breyne (bib0525) 2009; 106
Lozano (bib0520) 2014; 281
Kolupaeva (bib0545) 2003; 23
Hashem (bib0360) 2013; 503
Muhs (bib0425) 2011; 39
Martinez-Salas (bib0510) 2015; 206
Parsons (bib0315) 2009; 5
Imai (bib0535) 2016; 23
Pisareva, Pisarev (bib0605) 2014; 42
Ali (bib0105) 2001; 20
Hinnebusch (bib0015) 2014; 83
Kanamori, Nakashima (bib0380) 2001; 7
Matsuda, Mauro (bib0175) 2014; 111
Locker (bib0305) 2007; 26
Thompson (bib0120) 2001; 98
Gradi (bib0070) 1998; 95
Pestova (bib0245) 2008; 27
Yamamoto (bib0280) 2015; 34
Sweeney (bib0205) 2012; 86
Landry (bib0420) 2009; 23
Filbin (bib0310) 2013; 20
Fernandez (bib0165) 2014; 157
Kolupaeva (bib0210) 2007; 430
Kerr (bib0195) 2016; 6
Algire (bib0595) 2005; 20
Pestova (bib0600) 2000; 403
Ingolia (bib0005) 2011; 147
Zhou (bib0475) 2014; 345
Muhs (bib0480) 2015; 57
Spahn (bib0505) 2004; 118
de Breyne (bib0130) 2013; 171
Otto (bib0295) 2002; 8
Jan (bib0065) 2016; 3
Garaigorta, Chisari (bib0100) 2009; 6
Chamond (bib0550) 2014; 42
Francisco-Velilla (bib0170) 2015; 91
Svidritskiy (bib0445) 2014; 22
Behrmann (bib0450) 2015; 161
Jaafar (bib0250) 2016; 5
Kim (bib0270) 2011; 30
Sizova (bib0365) 1998; 72
Abeyrathne (bib0460) 2016; 5
Hertz (bib0560) 2013; 33
Rodriguez Pulido (bib0085) 2007; 364
Skabkin (bib0265) 2010; 24
Kozak (bib0180) 1979; 280
Spahn (bib0325) 2001; 291
Zhang (bib0485) 2016; 5
Fraser (bib0370) 2009; 16
Fernandez-Chamorro (bib0540) 2016; 6
Yamamoto (bib0345) 2014; 21
Weingarten-Gabbay (bib0570) 2016; 351
Pelletier, Sonenberg (bib0060) 1988; 334
Ramrath (bib0470) 2013; 110
Ratje (bib0465) 2010; 468
Carvajal (bib0565) 2016; 283
Pestova (bib0150) 1998; 12
Pilipenko (bib0155) 2000; 14
Berry (bib0300) 2011; 19
Koh (bib0415) 2014; 111
Wilson (bib0410) 2000; 102
Malygin (bib0290) 2013; 78
Kobayashi (bib0080) 2012; 86
Jang (bib0055) 1988; 62
Pestova (bib0515) 1996; 16
Pestova, Kolupaeva (bib0590) 2002; 16
Asnani (bib0240) 2015; 478
Pestova (bib0145) 1996; 16
Fuchs (bib0350) 2015; 112
Costantino (bib0430) 2008; 15
Pilipenko (bib0190) 1992; 68
Yamamoto (bib0435) 2007; 282
Uniacke (bib0030) 2012; 486
Hellen, de Breyne (bib0200) 2007; 81
Svitkin (bib0090) 2005; 25
Kumar (bib0585) 2016; 30
Perard (bib0225) 2013; 4
Belsham (bib0075) 2000; 74
Reynolds (bib0140) 1996; 2
Sasaki, Nakashima (bib0405) 2000; 97
Passmore (bib0340) 2007; 26
Gilbert (bib0125) 2010; 285
Schuler (bib0400) 2006; 13
Kozak (bib0020) 1978; 15
Lee (bib0355) 2015; 522
Budkevich (bib0440) 2011; 44
Ren (bib0495) 2012; 109
Shatsky (bib0035) 2014; 49
Robert (bib0115) 2006; 17
Shine, Dalgarno (bib0500) 1974; 71
Svitkin (bib0110) 1999; 73
Majzoub (bib0375) 2014; 159
Lancaster (bib0275) 2006; 12
Jan, Sarnow (bib0390) 2002; 324
Smirnova (bib0135) 2016; 121
des Georges (bib0330) 2015; 525
Lee (bib0040) 2016; 536
Kafasla (bib0555) 2009; 34
Kondrashov (bib0580) 2011; 145
Meyer (bib0045) 2015; 163
Fletcher, Jackson (bib0230) 2002; 76
Lukavsky (bib0235) 2009; 139
Quade (bib0285) 2015; 6
Garrey (bib0095) 2010; 84
Jackson (bib0050) 2013; 5
Boerneke (bib0320) 2014; 111
Terenin (bib0260) 2008; 15
Kieft (bib0610) 2001; 7
Sweeney (bib0160) 2014; 33
Uhlen (bib0010) 2016; 12
Archer (bib0025) 2016; 535
Chen, Sarnow (bib0185) 1995; 268
Nishiyama (bib0395) 2003; 31
Petrov (bib0490) 2016; 62
Murray (bib0455) 2016; 5
Li (bib0255) 2015; 25
Kieft (bib0215) 2007; 430
Majzoub (10.1016/j.tibs.2017.06.002_bib0375) 2014; 159
Uhlen (10.1016/j.tibs.2017.06.002_bib0010) 2016; 12
Kobayashi (10.1016/j.tibs.2017.06.002_bib0080) 2012; 86
Archer (10.1016/j.tibs.2017.06.002_bib0025) 2016; 535
Gradi (10.1016/j.tibs.2017.06.002_bib0070) 1998; 95
Asnani (10.1016/j.tibs.2017.06.002_bib0240) 2015; 478
Locker (10.1016/j.tibs.2017.06.002_bib0305) 2007; 26
Ren (10.1016/j.tibs.2017.06.002_bib0495) 2012; 109
Muhs (10.1016/j.tibs.2017.06.002_bib0425) 2011; 39
Ramrath (10.1016/j.tibs.2017.06.002_bib0470) 2013; 110
Zhou (10.1016/j.tibs.2017.06.002_bib0475) 2014; 345
Imai (10.1016/j.tibs.2017.06.002_bib0535) 2016; 23
Wilson (10.1016/j.tibs.2017.06.002_bib0410) 2000; 102
Xue (10.1016/j.tibs.2017.06.002_bib0575) 2015; 517
Uniacke (10.1016/j.tibs.2017.06.002_bib0030) 2012; 486
Li (10.1016/j.tibs.2017.06.002_bib0255) 2015; 25
Yu (10.1016/j.tibs.2017.06.002_bib0530) 2011; 39
Pelletier (10.1016/j.tibs.2017.06.002_bib0060) 1988; 334
Pestova (10.1016/j.tibs.2017.06.002_bib0245) 2008; 27
Kondrashov (10.1016/j.tibs.2017.06.002_bib0580) 2011; 145
Garaigorta (10.1016/j.tibs.2017.06.002_bib0100) 2009; 6
Abeyrathne (10.1016/j.tibs.2017.06.002_bib0460) 2016; 5
Costantino (10.1016/j.tibs.2017.06.002_bib0430) 2008; 15
Pestova (10.1016/j.tibs.2017.06.002_bib0600) 2000; 403
Berry (10.1016/j.tibs.2017.06.002_bib0300) 2011; 19
Svitkin (10.1016/j.tibs.2017.06.002_bib0110) 1999; 73
Koh (10.1016/j.tibs.2017.06.002_bib0415) 2014; 111
Yamamoto (10.1016/j.tibs.2017.06.002_bib0435) 2007; 282
Thompson (10.1016/j.tibs.2017.06.002_bib0120) 2001; 98
Fernandez (10.1016/j.tibs.2017.06.002_bib0165) 2014; 157
des Georges (10.1016/j.tibs.2017.06.002_bib0330) 2015; 525
Lee (10.1016/j.tibs.2017.06.002_bib0355) 2015; 522
Lukavsky (10.1016/j.tibs.2017.06.002_bib0235) 2009; 139
Muhs (10.1016/j.tibs.2017.06.002_bib0480) 2015; 57
Skabkin (10.1016/j.tibs.2017.06.002_bib0265) 2010; 24
Lee (10.1016/j.tibs.2017.06.002_bib0040) 2016; 536
Spahn (10.1016/j.tibs.2017.06.002_bib0505) 2004; 118
Petrov (10.1016/j.tibs.2017.06.002_bib0490) 2016; 62
Passmore (10.1016/j.tibs.2017.06.002_bib0340) 2007; 26
Jackson (10.1016/j.tibs.2017.06.002_bib0050) 2013; 5
de Breyne (10.1016/j.tibs.2017.06.002_bib0525) 2009; 106
Jang (10.1016/j.tibs.2017.06.002_bib0055) 1988; 62
Llacer (10.1016/j.tibs.2017.06.002_bib0335) 2015; 59
Chen (10.1016/j.tibs.2017.06.002_bib0185) 1995; 268
Kolupaeva (10.1016/j.tibs.2017.06.002_bib0210) 2007; 430
Perard (10.1016/j.tibs.2017.06.002_bib0225) 2013; 4
Boerneke (10.1016/j.tibs.2017.06.002_bib0320) 2014; 111
Shine (10.1016/j.tibs.2017.06.002_bib0500) 1974; 71
Jan (10.1016/j.tibs.2017.06.002_bib0065) 2016; 3
Pfingsten (10.1016/j.tibs.2017.06.002_bib0385) 2006; 314
Rodriguez Pulido (10.1016/j.tibs.2017.06.002_bib0085) 2007; 364
Lozano (10.1016/j.tibs.2017.06.002_bib0520) 2014; 281
Garrey (10.1016/j.tibs.2017.06.002_bib0095) 2010; 84
Pestova (10.1016/j.tibs.2017.06.002_bib0590) 2002; 16
Kolupaeva (10.1016/j.tibs.2017.06.002_bib0545) 2003; 23
Matsuda (10.1016/j.tibs.2017.06.002_bib0175) 2014; 111
Svitkin (10.1016/j.tibs.2017.06.002_bib0090) 2005; 25
Malygin (10.1016/j.tibs.2017.06.002_bib0290) 2013; 78
Fletcher (10.1016/j.tibs.2017.06.002_bib0230) 2002; 76
Martinez-Salas (10.1016/j.tibs.2017.06.002_bib0510) 2015; 206
Kieft (10.1016/j.tibs.2017.06.002_bib0215) 2007; 430
Jaafar (10.1016/j.tibs.2017.06.002_bib0250) 2016; 5
Belsham (10.1016/j.tibs.2017.06.002_bib0075) 2000; 74
Sizova (10.1016/j.tibs.2017.06.002_bib0365) 1998; 72
Budkevich (10.1016/j.tibs.2017.06.002_bib0440) 2011; 44
Terenin (10.1016/j.tibs.2017.06.002_bib0260) 2008; 15
Hertz (10.1016/j.tibs.2017.06.002_bib0560) 2013; 33
Pestova (10.1016/j.tibs.2017.06.002_bib0150) 1998; 12
Pilipenko (10.1016/j.tibs.2017.06.002_bib0155) 2000; 14
Sweeney (10.1016/j.tibs.2017.06.002_bib0160) 2014; 33
Robert (10.1016/j.tibs.2017.06.002_bib0115) 2006; 17
Gilbert (10.1016/j.tibs.2017.06.002_bib0125) 2010; 285
Parsons (10.1016/j.tibs.2017.06.002_bib0315) 2009; 5
Ingolia (10.1016/j.tibs.2017.06.002_bib0005) 2011; 147
Ali (10.1016/j.tibs.2017.06.002_bib0105) 2001; 20
Kim (10.1016/j.tibs.2017.06.002_bib0270) 2011; 30
Smirnova (10.1016/j.tibs.2017.06.002_bib0135) 2016; 121
Hinnebusch (10.1016/j.tibs.2017.06.002_bib0015) 2014; 83
de Breyne (10.1016/j.tibs.2017.06.002_bib0130) 2013; 171
Kumar (10.1016/j.tibs.2017.06.002_bib0585) 2016; 30
Sweeney (10.1016/j.tibs.2017.06.002_bib0205) 2012; 86
Meyer (10.1016/j.tibs.2017.06.002_bib0045) 2015; 163
Pisareva (10.1016/j.tibs.2017.06.002_bib0605) 2014; 42
Hashem (10.1016/j.tibs.2017.06.002_bib0360) 2013; 503
Sasaki (10.1016/j.tibs.2017.06.002_bib0405) 2000; 97
Svidritskiy (10.1016/j.tibs.2017.06.002_bib0445) 2014; 22
Algire (10.1016/j.tibs.2017.06.002_bib0595) 2005; 20
Hellen (10.1016/j.tibs.2017.06.002_bib0200) 2007; 81
Yamamoto (10.1016/j.tibs.2017.06.002_bib0280) 2015; 34
Carvajal (10.1016/j.tibs.2017.06.002_bib0565) 2016; 283
Kozak (10.1016/j.tibs.2017.06.002_bib0180) 1979; 280
Spahn (10.1016/j.tibs.2017.06.002_bib0325) 2001; 291
Kozak (10.1016/j.tibs.2017.06.002_bib0020) 1978; 15
Pestova (10.1016/j.tibs.2017.06.002_bib0515) 1996; 16
Quade (10.1016/j.tibs.2017.06.002_bib0285) 2015; 6
Chamond (10.1016/j.tibs.2017.06.002_bib0550) 2014; 42
Nishiyama (10.1016/j.tibs.2017.06.002_bib0395) 2003; 31
Schuler (10.1016/j.tibs.2017.06.002_bib0400) 2006; 13
Filbin (10.1016/j.tibs.2017.06.002_bib0310) 2013; 20
Otto (10.1016/j.tibs.2017.06.002_bib0295) 2002; 8
Pestova (10.1016/j.tibs.2017.06.002_bib0145) 1996; 16
Kerr (10.1016/j.tibs.2017.06.002_bib0195) 2016; 6
Landry (10.1016/j.tibs.2017.06.002_bib0420) 2009; 23
Kanamori (10.1016/j.tibs.2017.06.002_bib0380) 2001; 7
Francisco-Velilla (10.1016/j.tibs.2017.06.002_bib0170) 2015; 91
Fuchs (10.1016/j.tibs.2017.06.002_bib0350) 2015; 112
Kafasla (10.1016/j.tibs.2017.06.002_bib0555) 2009; 34
Zhang (10.1016/j.tibs.2017.06.002_bib0485) 2016; 5
Fernandez-Chamorro (10.1016/j.tibs.2017.06.002_bib0540) 2016; 6
Behrmann (10.1016/j.tibs.2017.06.002_bib0450) 2015; 161
Reynolds (10.1016/j.tibs.2017.06.002_bib0140) 1996; 2
Lancaster (10.1016/j.tibs.2017.06.002_bib0275) 2006; 12
Pilipenko (10.1016/j.tibs.2017.06.002_bib0190) 1992; 68
Jan (10.1016/j.tibs.2017.06.002_bib0390) 2002; 324
Murray (10.1016/j.tibs.2017.06.002_bib0455) 2016; 5
Kieft (10.1016/j.tibs.2017.06.002_bib0610) 2001; 7
Lukavsky (10.1016/j.tibs.2017.06.002_bib0220) 2003; 10
Yamamoto (10.1016/j.tibs.2017.06.002_bib0345) 2014; 21
Weingarten-Gabbay (10.1016/j.tibs.2017.06.002_bib0570) 2016; 351
Ratje (10.1016/j.tibs.2017.06.002_bib0465) 2010; 468
Shatsky (10.1016/j.tibs.2017.06.002_bib0035) 2014; 49
Fraser (10.1016/j.tibs.2017.06.002_bib0370) 2009; 16
References_xml – volume: 86
  start-page: 1468
  year: 2012
  end-page: 1486
  ident: bib0205
  article-title: A distinct class of internal ribosomal entry site in members of the
  publication-title: J. Virol.
  contributor:
    fullname: Sweeney
– volume: 33
  start-page: 1016
  year: 2013
  end-page: 1026
  ident: bib0560
  article-title: Ribosomal protein S25 dependency reveals a common mechanism for diverse internal ribosome entry sites and ribosome shunting
  publication-title: Mol. Cell. Biol.
  contributor:
    fullname: Hertz
– volume: 12
  start-page: 894
  year: 2006
  end-page: 902
  ident: bib0275
  article-title: Initiation factor-independent translation mediated by the hepatitis C virus internal ribosome entry site
  publication-title: RNA
  contributor:
    fullname: Lancaster
– volume: 291
  start-page: 1959
  year: 2001
  end-page: 1962
  ident: bib0325
  article-title: Hepatitis C virus IRES RNA-induced changes in the conformation of the 40s ribosomal subunit
  publication-title: Science
  contributor:
    fullname: Spahn
– volume: 522
  start-page: 111
  year: 2015
  end-page: 114
  ident: bib0355
  article-title: eIF3 targets cell-proliferation messenger RNAs for translational activation or repression
  publication-title: Nature
  contributor:
    fullname: Lee
– volume: 97
  start-page: 1512
  year: 2000
  end-page: 1515
  ident: bib0405
  article-title: Methionine-independent initiation of translation in the capsid protein of an insect RNA virus
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  contributor:
    fullname: Nakashima
– volume: 42
  start-page: 10373
  year: 2014
  end-page: 10384
  ident: bib0550
  article-title: 40S recruitment in the absence of eIF4G/4A by EMCV IRES refines the model for translation initiation on the archetype of type II IRESs
  publication-title: Nucleic Acids Res.
  contributor:
    fullname: Chamond
– volume: 76
  start-page: 5024
  year: 2002
  end-page: 5033
  ident: bib0230
  article-title: Pestivirus internal ribosome entry site (IRES) structure and function: elements in the 5′ untranslated region important for IRES function
  publication-title: J. Virol.
  contributor:
    fullname: Jackson
– volume: 12
  start-page: 862
  year: 2016
  ident: bib0010
  article-title: Transcriptomics resources of human tissues and organs
  publication-title: Mol. Syst. Biol.
  contributor:
    fullname: Uhlen
– volume: 83
  start-page: 779
  year: 2014
  end-page: 812
  ident: bib0015
  article-title: The scanning mechanism of eukaryotic translation initiation
  publication-title: Annu. Rev. Biochem.
  contributor:
    fullname: Hinnebusch
– volume: 3
  start-page: 283
  year: 2016
  end-page: 307
  ident: bib0065
  article-title: A cap-to-tail guide to mRNA translation strategies in virus-infected cells
  publication-title: Annu. Rev. Virol.
  contributor:
    fullname: Jan
– volume: 334
  start-page: 320
  year: 1988
  end-page: 325
  ident: bib0060
  article-title: Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA
  publication-title: Nature
  contributor:
    fullname: Sonenberg
– volume: 5
  start-page: e13429
  year: 2016
  ident: bib0485
  article-title: Kinetics of initiating polypeptide elongation in an IRES-dependent system
  publication-title: Elife
  contributor:
    fullname: Zhang
– volume: 20
  start-page: 251
  year: 2005
  end-page: 262
  ident: bib0595
  article-title: P
  publication-title: Mol. Cell
  contributor:
    fullname: Algire
– volume: 535
  start-page: 570
  year: 2016
  end-page: 574
  ident: bib0025
  article-title: Dynamics of ribosome scanning and recycling revealed by translation complex profiling
  publication-title: Nature
  contributor:
    fullname: Archer
– volume: 73
  start-page: 3467
  year: 1999
  end-page: 3472
  ident: bib0110
  article-title: Eukaryotic initiation factor 4GII (eIF4GII), but not eIF4GI, cleavage correlates with inhibition of host cell protein synthesis after human rhinovirus infection
  publication-title: J. Virol.
  contributor:
    fullname: Svitkin
– volume: 102
  start-page: 511
  year: 2000
  end-page: 520
  ident: bib0410
  article-title: Initiation of protein synthesis from the A site of the ribosome
  publication-title: Cell
  contributor:
    fullname: Wilson
– volume: 19
  start-page: 1456
  year: 2011
  end-page: 1466
  ident: bib0300
  article-title: Crystal structure of the HCV IRES central domain reveals strategy for start-codon positioning
  publication-title: Structure
  contributor:
    fullname: Berry
– volume: 147
  start-page: 789
  year: 2011
  end-page: 802
  ident: bib0005
  article-title: Ribosome profiling of mouse embryonic stem cells reveals the complexity and dynamics of mammalian proteomes
  publication-title: Cell
  contributor:
    fullname: Ingolia
– volume: 26
  start-page: 795
  year: 2007
  end-page: 805
  ident: bib0305
  article-title: HCV and CSFV IRES domain II mediate eIF2 release during 80S ribosome assembly
  publication-title: EMBO J.
  contributor:
    fullname: Locker
– volume: 112
  start-page: 319
  year: 2015
  end-page: 325
  ident: bib0350
  article-title: Kinetic pathway of 40S ribosomal subunit recruitment to hepatitis C virus internal ribosome entry site
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  contributor:
    fullname: Fuchs
– volume: 12
  start-page: 67
  year: 1998
  end-page: 83
  ident: bib0150
  article-title: A prokaryotic-like mode of cytoplasmic eukaryotic ribosome binding to the initiation codon during internal translation initiation of hepatitis C and classical swine fever virus RNAs
  publication-title: Genes Dev.
  contributor:
    fullname: Pestova
– volume: 30
  start-page: 1573
  year: 2016
  end-page: 1588
  ident: bib0585
  article-title: Toward the mechanism of eIF4F-mediated ribosomal attachment to mammalian capped mRNAs
  publication-title: Genes Dev.
  contributor:
    fullname: Kumar
– volume: 98
  start-page: 12972
  year: 2001
  end-page: 12977
  ident: bib0120
  article-title: Internal initiation in
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  contributor:
    fullname: Thompson
– volume: 139
  start-page: 166
  year: 2009
  end-page: 171
  ident: bib0235
  article-title: Structure and function of HCV IRES domains
  publication-title: Virus Res.
  contributor:
    fullname: Lukavsky
– volume: 72
  start-page: 4775
  year: 1998
  end-page: 4782
  ident: bib0365
  article-title: Specific interaction of eukaryotic translation initiation factor 3 with the 5′ nontranslated regions of hepatitis C virus and classical swine fever virus RNAs
  publication-title: J. Virol.
  contributor:
    fullname: Sizova
– volume: 6
  start-page: 513
  year: 2009
  end-page: 522
  ident: bib0100
  article-title: Hepatitis C virus blocks interferon effector function by inducing protein kinase R phosphorylation
  publication-title: Cell Host Microbe
  contributor:
    fullname: Chisari
– volume: 111
  start-page: 15385
  year: 2014
  end-page: 15389
  ident: bib0175
  article-title: Base pairing between hepatitis C virus RNA and 18S rRNA is required for IRES-dependent translation initiation in vivo
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  contributor:
    fullname: Mauro
– volume: 430
  start-page: 409
  year: 2007
  end-page: 439
  ident: bib0210
  article-title: In vitro reconstitution and biochemical characterization of translation initiation by internal ribosomal entry
  publication-title: Methods Enzymol.
  contributor:
    fullname: Kolupaeva
– volume: 283
  start-page: 2508
  year: 2016
  end-page: 2527
  ident: bib0565
  article-title: Structural domains within the HIV-1 mRNA and the ribosomal protein S25 influence cap-independent translation initiation
  publication-title: FEBS J.
  contributor:
    fullname: Carvajal
– volume: 86
  start-page: 10686
  year: 2012
  end-page: 10694
  ident: bib0080
  article-title: Site-specific cleavage of the host poly(A) binding protein by the encephalomyocarditis virus 3C proteinase stimulates viral replication
  publication-title: J. Virol.
  contributor:
    fullname: Kobayashi
– volume: 171
  start-page: 366
  year: 2013
  end-page: 381
  ident: bib0130
  article-title: Translation initiation is driven by different mechanisms on the HIV-1 and HIV-2 genomic RNAs
  publication-title: Virus Res.
  contributor:
    fullname: de Breyne
– volume: 109
  start-page: E630
  year: 2012
  end-page: E639
  ident: bib0495
  article-title: Alternative reading frame selection mediated by a tRNA-like domain of an internal ribosome entry site
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  contributor:
    fullname: Ren
– volume: 121
  start-page: 228
  year: 2016
  end-page: 237
  ident: bib0135
  article-title: Does HIV-1 mRNA 5′-untranslated region bear an internal ribosome entry site?
  publication-title: Biochimie
  contributor:
    fullname: Smirnova
– volume: 106
  start-page: 9197
  year: 2009
  end-page: 9202
  ident: bib0525
  article-title: Direct functional interaction of initiation factor eIF4G with type 1 internal ribosomal entry sites
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  contributor:
    fullname: de Breyne
– volume: 6
  start-page: 37319
  year: 2016
  ident: bib0195
  article-title: Molecular analysis of the factorless internal ribosome entry site in cricket paralysis virus infection
  publication-title: Sci. Rep.
  contributor:
    fullname: Kerr
– volume: 7
  start-page: 266
  year: 2001
  end-page: 274
  ident: bib0380
  article-title: A tertiary structure model of the internal ribosome entry site (IRES) for methionine-independent initiation of translation
  publication-title: RNA
  contributor:
    fullname: Nakashima
– volume: 111
  start-page: 9139
  year: 2014
  end-page: 9144
  ident: bib0415
  article-title: Taura syndrome virus IRES initiates translation by binding its tRNA-mRNA-like structural element in the ribosomal decoding center
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  contributor:
    fullname: Koh
– volume: 95
  start-page: 11089
  year: 1998
  end-page: 11094
  ident: bib0070
  article-title: Proteolysis of human eukaryotic translation initiation factor eIF4GII, but not eIF4GI, coincides with the shutoff of host protein synthesis after poliovirus infection
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  contributor:
    fullname: Gradi
– volume: 25
  start-page: 10556
  year: 2005
  end-page: 10565
  ident: bib0090
  article-title: Eukaryotic translation initiation factor 4E availability controls the switch between cap-dependent and internal ribosomal entry site-mediated translation
  publication-title: Mol. Cell Biol.
  contributor:
    fullname: Svitkin
– volume: 285
  start-page: 29033
  year: 2010
  end-page: 29038
  ident: bib0125
  article-title: Alternative ways to think about cellular internal ribosome entry
  publication-title: J. Biol. Chem.
  contributor:
    fullname: Gilbert
– volume: 33
  start-page: 76
  year: 2014
  end-page: 92
  ident: bib0160
  article-title: The mechanism of translation initiation on type 1 picornavirus IRESs
  publication-title: EMBO J.
  contributor:
    fullname: Sweeney
– volume: 30
  start-page: 2454
  year: 2011
  end-page: 2464
  ident: bib0270
  article-title: eIF2A mediates translation of hepatitis C viral mRNA under stress conditions
  publication-title: EMBO J.
  contributor:
    fullname: Kim
– volume: 20
  start-page: 150
  year: 2013
  end-page: 158
  ident: bib0310
  article-title: HCV IRES manipulates the ribosome to promote the switch from translation initiation to elongation
  publication-title: Nat. Struct. Mol. Biol.
  contributor:
    fullname: Filbin
– volume: 159
  start-page: 1086
  year: 2014
  end-page: 1095
  ident: bib0375
  article-title: RACK1 controls IRES-mediated translation of viruses
  publication-title: Cell
  contributor:
    fullname: Majzoub
– volume: 268
  start-page: 415
  year: 1995
  end-page: 417
  ident: bib0185
  article-title: Initiation of protein synthesis by the eukaryotic translational apparatus on circular RNAs
  publication-title: Science
  contributor:
    fullname: Sarnow
– volume: 62
  start-page: 2636
  year: 1988
  end-page: 2643
  ident: bib0055
  article-title: A segment of the 5′ nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation
  publication-title: J. Virol.
  contributor:
    fullname: Jang
– volume: 7
  start-page: 194
  year: 2001
  end-page: 206
  ident: bib0610
  article-title: Mechanism of ribosome recruitment by hepatitis C IRES RNA
  publication-title: RNA
  contributor:
    fullname: Kieft
– volume: 23
  start-page: 859
  year: 2016
  end-page: 864
  ident: bib0535
  article-title: An accurately preorganized IRES RNA structure enables eIF4G capture for initiation of viral translation
  publication-title: Nat. Struct. Mol. Biol.
  contributor:
    fullname: Imai
– volume: 15
  start-page: 1109
  year: 1978
  end-page: 1123
  ident: bib0020
  article-title: How do eucaryotic ribosomes select initiation regions in messenger RNA?
  publication-title: Cell
  contributor:
    fullname: Kozak
– volume: 71
  start-page: 1342
  year: 1974
  end-page: 1346
  ident: bib0500
  article-title: The 3′ terminal sequence of
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  contributor:
    fullname: Dalgarno
– volume: 81
  start-page: 5850
  year: 2007
  end-page: 5863
  ident: bib0200
  article-title: A distinct group of hepacivirus/pestivirus-like internal ribosomal entry sites in members of diverse picornavirus genera: evidence for modular exchange of functional noncoding RNA elements by recombination
  publication-title: J. Virol.
  contributor:
    fullname: de Breyne
– volume: 74
  start-page: 272
  year: 2000
  end-page: 280
  ident: bib0075
  article-title: Foot-and-mouth disease virus 3C protease induces cleavage of translation initiation factors eIF4A and eIF4G within infected cells
  publication-title: J. Virol.
  contributor:
    fullname: Belsham
– volume: 20
  start-page: 4233
  year: 2001
  end-page: 4242
  ident: bib0105
  article-title: Truncated initiation factor eIF4G lacking an eIF4E binding site can support capped mRNA translation
  publication-title: EMBO J.
  contributor:
    fullname: Ali
– volume: 2
  start-page: 867
  year: 1996
  end-page: 878
  ident: bib0140
  article-title: Internal initiation of translation of hepatitis C virus RNA: the ribosome entry site is at the authentic initiation codon
  publication-title: RNA
  contributor:
    fullname: Reynolds
– volume: 111
  start-page: 15952
  year: 2014
  end-page: 15957
  ident: bib0320
  article-title: Functional conservation despite structural divergence in ligand-responsive RNA switches
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  contributor:
    fullname: Boerneke
– volume: 44
  start-page: 214
  year: 2011
  end-page: 224
  ident: bib0440
  article-title: Structure and dynamics of the mammalian ribosomal pretranslocation complex
  publication-title: Mol. Cell
  contributor:
    fullname: Budkevich
– volume: 27
  start-page: 1060
  year: 2008
  end-page: 1072
  ident: bib0245
  article-title: eIF2-dependent and eIF2-independent modes of initiation on the CSFV IRES: a common role of domain II
  publication-title: EMBO J.
  contributor:
    fullname: Pestova
– volume: 281
  start-page: 3685
  year: 2014
  end-page: 3700
  ident: bib0520
  article-title: Magnesium-dependent folding of a picornavirus IRES element modulates RNA conformation and eIF4G interaction
  publication-title: FEBS J.
  contributor:
    fullname: Lozano
– volume: 536
  start-page: 96
  year: 2016
  end-page: 99
  ident: bib0040
  article-title: eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation
  publication-title: Nature
  contributor:
    fullname: Lee
– volume: 161
  start-page: 845
  year: 2015
  end-page: 857
  ident: bib0450
  article-title: Structural snapshots of actively translating human ribosomes
  publication-title: Cell
  contributor:
    fullname: Behrmann
– volume: 403
  start-page: 332
  year: 2000
  end-page: 335
  ident: bib0600
  article-title: The joining of ribosomal subunits in eukaryotes requires eIF5B
  publication-title: Nature
  contributor:
    fullname: Pestova
– volume: 16
  start-page: 6859
  year: 1996
  end-page: 6869
  ident: bib0145
  article-title: Canonical eukaryotic initiation factors determine initiation of translation by internal ribosomal entry
  publication-title: Mol. Cell. Biol.
  contributor:
    fullname: Pestova
– volume: 206
  start-page: 62
  year: 2015
  end-page: 73
  ident: bib0510
  article-title: Picornavirus IRES elements: RNA structure and host protein interactions
  publication-title: Virus Res.
  contributor:
    fullname: Martinez-Salas
– volume: 280
  start-page: 82
  year: 1979
  end-page: 85
  ident: bib0180
  article-title: Inability of circular mRNA to attach to eukaryotic ribosomes
  publication-title: Nature
  contributor:
    fullname: Kozak
– volume: 59
  start-page: 399
  year: 2015
  end-page: 412
  ident: bib0335
  article-title: Conformational differences between open and closed states of the eukaryotic translation initiation complex
  publication-title: Mol. Cell
  contributor:
    fullname: Llacer
– volume: 5
  start-page: a011569
  year: 2013
  ident: bib0050
  article-title: The current status of vertebrate cellular mRNA IRESs
  publication-title: Cold Spring Harb. Perspect. Biol.
  contributor:
    fullname: Jackson
– volume: 23
  start-page: 687
  year: 2003
  end-page: 698
  ident: bib0545
  article-title: Eukaryotic initiation factors 4G and 4A mediate conformational changes downstream of the initiation codon of the encephalomyocarditis virus internal ribosomal entry site
  publication-title: Mol. Cell. Biol.
  contributor:
    fullname: Kolupaeva
– volume: 430
  start-page: 333
  year: 2007
  end-page: 371
  ident: bib0215
  article-title: Structural methods for studying IRES function
  publication-title: Methods Enzymol.
  contributor:
    fullname: Kieft
– volume: 84
  start-page: 1124
  year: 2010
  end-page: 1138
  ident: bib0095
  article-title: Host and viral translational mechanisms during cricket paralysis virus infection
  publication-title: J. Virol.
  contributor:
    fullname: Garrey
– volume: 39
  start-page: 5264
  year: 2011
  end-page: 5275
  ident: bib0425
  article-title: Structural basis for the binding of IRES RNAs to the head of the ribosomal 40S subunit
  publication-title: Nucleic Acids Res.
  contributor:
    fullname: Muhs
– volume: 34
  start-page: 556
  year: 2009
  end-page: 568
  ident: bib0555
  article-title: Polypyrimidine tract binding protein stabilizes the encephalomyocarditis virus IRES structure via binding multiple sites in a unique orientation
  publication-title: Mol. Cell
  contributor:
    fullname: Kafasla
– volume: 34
  start-page: 3042
  year: 2015
  end-page: 3058
  ident: bib0280
  article-title: Molecular architecture of the ribosome-bound hepatitis C virus internal ribosomal entry site RNA
  publication-title: EMBO J.
  contributor:
    fullname: Yamamoto
– volume: 364
  start-page: 466
  year: 2007
  end-page: 474
  ident: bib0085
  article-title: Foot-and-mouth disease virus infection induces proteolytic cleavage of PTB, eIF3a,b, and PABP RNA-binding proteins
  publication-title: Virology
  contributor:
    fullname: Rodriguez Pulido
– volume: 16
  start-page: 397
  year: 2009
  end-page: 404
  ident: bib0370
  article-title: The pathway of hepatitis C virus mRNA recruitment to the human ribosome
  publication-title: Nat. Struct. Mol. Biol.
  contributor:
    fullname: Fraser
– volume: 157
  start-page: 823
  year: 2014
  end-page: 831
  ident: bib0165
  article-title: Initiation of translation by cricket paralysis virus IRES requires its translocation in the ribosome
  publication-title: Cell
  contributor:
    fullname: Fernandez
– volume: 24
  start-page: 1787
  year: 2010
  end-page: 1801
  ident: bib0265
  article-title: Activities of Ligatin and MCT-1/DENR in eukaryotic translation initiation and ribosomal recycling
  publication-title: Genes Dev.
  contributor:
    fullname: Skabkin
– volume: 13
  start-page: 1092
  year: 2006
  end-page: 1096
  ident: bib0400
  article-title: Structure of the ribosome-bound cricket paralysis virus IRES RNA
  publication-title: Nat. Struct. Mol. Biol.
  contributor:
    fullname: Schuler
– volume: 5
  start-page: e21198
  year: 2016
  ident: bib0250
  article-title: Translation initiation by the hepatitis C virus IRES requires eIF1A and ribosomal complex remodeling
  publication-title: Elife
  contributor:
    fullname: Jaafar
– volume: 22
  start-page: 1210
  year: 2014
  end-page: 1218
  ident: bib0445
  article-title: Structures of yeast 80S ribosome-tRNA complexes in the rotated and nonrotated conformations
  publication-title: Structure
  contributor:
    fullname: Svidritskiy
– volume: 17
  start-page: 4632
  year: 2006
  end-page: 4644
  ident: bib0115
  article-title: Initiation of protein synthesis by hepatitis C virus is refractory to reduced eIF2*GTP*Met-tRNAiMet ternary complex availability
  publication-title: Mol. Biol. Cell
  contributor:
    fullname: Robert
– volume: 118
  start-page: 465
  year: 2004
  end-page: 475
  ident: bib0505
  article-title: Cryo-EM visualization of a viral internal ribosome entry site bound to human ribosomes: the IRES functions as an RNA-based translation factor
  publication-title: Cell
  contributor:
    fullname: Spahn
– volume: 26
  start-page: 41
  year: 2007
  end-page: 50
  ident: bib0340
  article-title: The eukaryotic translation initiation factors eIF1 and eIF1A induce an open conformation of the 40S ribosome
  publication-title: Mol. Cell
  contributor:
    fullname: Passmore
– volume: 57
  start-page: 422
  year: 2015
  end-page: 432
  ident: bib0480
  article-title: Cryo-EM of ribosomal 80S complexes with termination factors reveals the translocated cricket paralysis virus IRES
  publication-title: Mol. Cell
  contributor:
    fullname: Muhs
– volume: 351
  start-page: aad4939
  year: 2016
  ident: bib0570
  article-title: Systematic discovery of cap-independent translation sequences in human and viral genomes
  publication-title: Science
  contributor:
    fullname: Weingarten-Gabbay
– volume: 10
  start-page: 1033
  year: 2003
  end-page: 1038
  ident: bib0220
  article-title: Structure of HCV IRES domain II determined by NMR
  publication-title: Nat. Struct. Biol.
  contributor:
    fullname: Lukavsky
– volume: 21
  start-page: 721
  year: 2014
  end-page: 727
  ident: bib0345
  article-title: Structure of the mammalian 80S initiation complex with initiation factor 5B on HCV-IRES RNA
  publication-title: Nat. Struct. Mol. Biol.
  contributor:
    fullname: Yamamoto
– volume: 468
  start-page: 713
  year: 2010
  end-page: 716
  ident: bib0465
  article-title: Head swivel on the ribosome facilitates translocation by means of intra-subunit tRNA hybrid sites
  publication-title: Nature
  contributor:
    fullname: Ratje
– volume: 16
  start-page: 2906
  year: 2002
  end-page: 2922
  ident: bib0590
  article-title: The roles of individual eukaryotic translation initiation factors in ribosomal scanning and initiation codon selection
  publication-title: Genes Dev.
  contributor:
    fullname: Kolupaeva
– volume: 25
  start-page: 320
  year: 2015
  end-page: 329
  ident: bib0255
  article-title: To translate, or not to translate: viral and host mRNA regulation by interferon-stimulated genes
  publication-title: Trends Cell Biol.
  contributor:
    fullname: Li
– volume: 68
  start-page: 119
  year: 1992
  end-page: 131
  ident: bib0190
  article-title: Prokaryotic-like cis elements in the cap-independent internal initiation of translation on picornavirus RNA
  publication-title: Cell
  contributor:
    fullname: Pilipenko
– volume: 503
  start-page: 539
  year: 2013
  end-page: 543
  ident: bib0360
  article-title: Hepatitis-C-virus-like internal ribosome entry sites displace eIF3 to gain access to the 40S subunit
  publication-title: Nature
  contributor:
    fullname: Hashem
– volume: 6
  start-page: 7646
  year: 2015
  ident: bib0285
  article-title: Cryo-EM structure of hepatitis C virus IRES bound to the human ribosome at 3.9-Å resolution
  publication-title: Nat. Commun.
  contributor:
    fullname: Quade
– volume: 5
  start-page: e13567
  year: 2016
  ident: bib0455
  article-title: Structural characterization of ribosome recruitment and translocation by type IV IRES
  publication-title: Elife
  contributor:
    fullname: Murray
– volume: 110
  start-page: 20964
  year: 2013
  end-page: 20969
  ident: bib0470
  article-title: Visualization of two transfer RNAs trapped in transit during elongation factor G-mediated translocation
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  contributor:
    fullname: Ramrath
– volume: 91
  start-page: 3
  year: 2015
  end-page: 12
  ident: bib0170
  article-title: RNA–protein interaction methods to study viral IRES elements
  publication-title: Methods
  contributor:
    fullname: Francisco-Velilla
– volume: 14
  start-page: 2028
  year: 2000
  end-page: 2045
  ident: bib0155
  article-title: A cell cycle-dependent protein serves as a template-specific translation initiation factor
  publication-title: Genes Dev.
  contributor:
    fullname: Pilipenko
– volume: 15
  start-page: 57
  year: 2008
  end-page: 64
  ident: bib0430
  article-title: tRNA-mRNA mimicry drives translation initiation from a viral IRES
  publication-title: Nat. Struct. Mol. Biol.
  contributor:
    fullname: Costantino
– volume: 145
  start-page: 383
  year: 2011
  end-page: 397
  ident: bib0580
  article-title: Ribosome-mediated specificity in Hox mRNA translation and vertebrate tissue patterning
  publication-title: Cell
  contributor:
    fullname: Kondrashov
– volume: 23
  start-page: 2753
  year: 2009
  end-page: 2764
  ident: bib0420
  article-title: RPS25 is essential for translation initiation by the Dicistroviridae and hepatitis C viral IRESs
  publication-title: Genes Dev.
  contributor:
    fullname: Landry
– volume: 78
  start-page: 53
  year: 2013
  end-page: 59
  ident: bib0290
  article-title: Proteins of the human 40S ribosomal subunit involved in hepatitis C IRES binding as revealed from fluorescent labeling
  publication-title: Biochemistry (Mosc.)
  contributor:
    fullname: Malygin
– volume: 345
  start-page: 1188
  year: 2014
  end-page: 1191
  ident: bib0475
  article-title: How the ribosome hands the A-site tRNA to the P site during EF-G-catalyzed translocation
  publication-title: Science
  contributor:
    fullname: Zhou
– volume: 486
  start-page: 126
  year: 2012
  end-page: 129
  ident: bib0030
  article-title: An oxygen-regulated switch in the protein synthesis machinery
  publication-title: Nature
  contributor:
    fullname: Uniacke
– volume: 478
  start-page: 61
  year: 2015
  end-page: 74
  ident: bib0240
  article-title: Widespread distribution and structural diversity of type IV IRESs in members of Picornaviridae
  publication-title: Virology
  contributor:
    fullname: Asnani
– volume: 39
  start-page: 4851
  year: 2011
  end-page: 4865
  ident: bib0530
  article-title: Common conformational changes induced in type 2 picornavirus IRESs by cognate trans-acting factors
  publication-title: Nucleic Acids Res.
  contributor:
    fullname: Yu
– volume: 31
  start-page: 2434
  year: 2003
  end-page: 2442
  ident: bib0395
  article-title: Structural elements in the internal ribosome entry site of
  publication-title: Nucleic Acids Res.
  contributor:
    fullname: Nishiyama
– volume: 5
  start-page: 823
  year: 2009
  end-page: 825
  ident: bib0315
  article-title: Conformational inhibition of the hepatitis C virus internal ribosome entry site RNA
  publication-title: Nat. Chem. Biol.
  contributor:
    fullname: Parsons
– volume: 8
  start-page: 913
  year: 2002
  end-page: 923
  ident: bib0295
  article-title: Ribosomal proteins mediate the hepatitis C virus IRES–HeLa 40S interaction
  publication-title: RNA
  contributor:
    fullname: Otto
– volume: 15
  start-page: 836
  year: 2008
  end-page: 841
  ident: bib0260
  article-title: Eukaryotic translation initiation machinery can operate in a bacterial-like mode without eIF2
  publication-title: Nat. Struct. Mol. Biol.
  contributor:
    fullname: Terenin
– volume: 4
  start-page: 1612
  year: 2013
  ident: bib0225
  article-title: Structure of the full-length HCV IRES in solution
  publication-title: Nat. Commun.
  contributor:
    fullname: Perard
– volume: 5
  start-page: e14874
  year: 2016
  ident: bib0460
  article-title: Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome
  publication-title: Elife
  contributor:
    fullname: Abeyrathne
– volume: 49
  start-page: 164
  year: 2014
  end-page: 177
  ident: bib0035
  article-title: Transcriptome-wide studies uncover the diversity of modes of mRNA recruitment to eukaryotic ribosomes
  publication-title: Crit. Rev. Biochem. Mol. Biol.
  contributor:
    fullname: Shatsky
– volume: 163
  start-page: 999
  year: 2015
  end-page: 1010
  ident: bib0045
  article-title: 5′ UTR m
  publication-title: Cell
  contributor:
    fullname: Meyer
– volume: 6
  start-page: 24243
  year: 2016
  ident: bib0540
  article-title: Designing synthetic RNAs to determine the relevance of structural motifs in picornavirus IRES elements
  publication-title: Sci. Rep.
  contributor:
    fullname: Fernandez-Chamorro
– volume: 517
  start-page: 33
  year: 2015
  end-page: 38
  ident: bib0575
  article-title: RNA regulons in Hox 5′ UTRs confer ribosome specificity to gene regulation
  publication-title: Nature
  contributor:
    fullname: Xue
– volume: 525
  start-page: 491
  year: 2015
  end-page: 495
  ident: bib0330
  article-title: Structure of mammalian eIF3 in the context of the 43S preinitiation complex
  publication-title: Nature
  contributor:
    fullname: des Georges
– volume: 42
  start-page: 12052
  year: 2014
  end-page: 12069
  ident: bib0605
  article-title: EIF5 and eIF5B together stimulate 48S initiation complex formation during ribosomal scanning
  publication-title: Nucleic Acids Res.
  contributor:
    fullname: Pisarev
– volume: 324
  start-page: 889
  year: 2002
  end-page: 902
  ident: bib0390
  article-title: Factorless ribosome assembly on the internal ribosome entry site of cricket paralysis virus
  publication-title: J. Mol. Biol.
  contributor:
    fullname: Sarnow
– volume: 282
  start-page: 7770
  year: 2007
  end-page: 7776
  ident: bib0435
  article-title: Binding mode of the first aminoacyl-tRNA in translation initiation mediated by
  publication-title: J. Biol. Chem.
  contributor:
    fullname: Yamamoto
– volume: 62
  start-page: 92
  year: 2016
  end-page: 103
  ident: bib0490
  article-title: Multiple parallel pathways of translation initiation on the CrPV IRES
  publication-title: Mol. Cell
  contributor:
    fullname: Petrov
– volume: 16
  start-page: 6870
  year: 1996
  end-page: 6878
  ident: bib0515
  article-title: Functional dissection of eukaryotic initiation factor 4F: the 4A subunit and the central domain of the 4G subunit are sufficient to mediate internal entry of 43S preinitiation complexes
  publication-title: Mol. Cell. Biol.
  contributor:
    fullname: Pestova
– volume: 314
  start-page: 1450
  year: 2006
  end-page: 1454
  ident: bib0385
  article-title: Structural basis for ribosome recruitment and manipulation by a viral IRES RNA
  publication-title: Science
  contributor:
    fullname: Pfingsten
– volume: 76
  start-page: 5024
  year: 2002
  ident: 10.1016/j.tibs.2017.06.002_bib0230
  article-title: Pestivirus internal ribosome entry site (IRES) structure and function: elements in the 5′ untranslated region important for IRES function
  publication-title: J. Virol.
  doi: 10.1128/JVI.76.10.5024-5033.2002
  contributor:
    fullname: Fletcher
– volume: 21
  start-page: 721
  year: 2014
  ident: 10.1016/j.tibs.2017.06.002_bib0345
  article-title: Structure of the mammalian 80S initiation complex with initiation factor 5B on HCV-IRES RNA
  publication-title: Nat. Struct. Mol. Biol.
  doi: 10.1038/nsmb.2859
  contributor:
    fullname: Yamamoto
– volume: 14
  start-page: 2028
  year: 2000
  ident: 10.1016/j.tibs.2017.06.002_bib0155
  article-title: A cell cycle-dependent protein serves as a template-specific translation initiation factor
  publication-title: Genes Dev.
  doi: 10.1101/gad.14.16.2028
  contributor:
    fullname: Pilipenko
– volume: 26
  start-page: 795
  year: 2007
  ident: 10.1016/j.tibs.2017.06.002_bib0305
  article-title: HCV and CSFV IRES domain II mediate eIF2 release during 80S ribosome assembly
  publication-title: EMBO J.
  doi: 10.1038/sj.emboj.7601549
  contributor:
    fullname: Locker
– volume: 314
  start-page: 1450
  year: 2006
  ident: 10.1016/j.tibs.2017.06.002_bib0385
  article-title: Structural basis for ribosome recruitment and manipulation by a viral IRES RNA
  publication-title: Science
  doi: 10.1126/science.1133281
  contributor:
    fullname: Pfingsten
– volume: 522
  start-page: 111
  year: 2015
  ident: 10.1016/j.tibs.2017.06.002_bib0355
  article-title: eIF3 targets cell-proliferation messenger RNAs for translational activation or repression
  publication-title: Nature
  doi: 10.1038/nature14267
  contributor:
    fullname: Lee
– volume: 147
  start-page: 789
  year: 2011
  ident: 10.1016/j.tibs.2017.06.002_bib0005
  article-title: Ribosome profiling of mouse embryonic stem cells reveals the complexity and dynamics of mammalian proteomes
  publication-title: Cell
  doi: 10.1016/j.cell.2011.10.002
  contributor:
    fullname: Ingolia
– volume: 98
  start-page: 12972
  year: 2001
  ident: 10.1016/j.tibs.2017.06.002_bib0120
  article-title: Internal initiation in Saccharomyces cerevisiae mediated by an initiator tRNA/eIF2-independent internal ribosome entry site element
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  doi: 10.1073/pnas.241286698
  contributor:
    fullname: Thompson
– volume: 268
  start-page: 415
  year: 1995
  ident: 10.1016/j.tibs.2017.06.002_bib0185
  article-title: Initiation of protein synthesis by the eukaryotic translational apparatus on circular RNAs
  publication-title: Science
  doi: 10.1126/science.7536344
  contributor:
    fullname: Chen
– volume: 91
  start-page: 3
  year: 2015
  ident: 10.1016/j.tibs.2017.06.002_bib0170
  article-title: RNA–protein interaction methods to study viral IRES elements
  publication-title: Methods
  doi: 10.1016/j.ymeth.2015.06.023
  contributor:
    fullname: Francisco-Velilla
– volume: 171
  start-page: 366
  year: 2013
  ident: 10.1016/j.tibs.2017.06.002_bib0130
  article-title: Translation initiation is driven by different mechanisms on the HIV-1 and HIV-2 genomic RNAs
  publication-title: Virus Res.
  doi: 10.1016/j.virusres.2012.10.006
  contributor:
    fullname: de Breyne
– volume: 20
  start-page: 251
  year: 2005
  ident: 10.1016/j.tibs.2017.06.002_bib0595
  article-title: Pi release from eIF2, not GTP hydrolysis, is the step controlled by start-site selection during eukaryotic translation initiation
  publication-title: Mol. Cell
  doi: 10.1016/j.molcel.2005.09.008
  contributor:
    fullname: Algire
– volume: 16
  start-page: 6859
  year: 1996
  ident: 10.1016/j.tibs.2017.06.002_bib0145
  article-title: Canonical eukaryotic initiation factors determine initiation of translation by internal ribosomal entry
  publication-title: Mol. Cell. Biol.
  doi: 10.1128/MCB.16.12.6859
  contributor:
    fullname: Pestova
– volume: 74
  start-page: 272
  year: 2000
  ident: 10.1016/j.tibs.2017.06.002_bib0075
  article-title: Foot-and-mouth disease virus 3C protease induces cleavage of translation initiation factors eIF4A and eIF4G within infected cells
  publication-title: J. Virol.
  doi: 10.1128/JVI.74.1.272-280.2000
  contributor:
    fullname: Belsham
– volume: 285
  start-page: 29033
  year: 2010
  ident: 10.1016/j.tibs.2017.06.002_bib0125
  article-title: Alternative ways to think about cellular internal ribosome entry
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.R110.150532
  contributor:
    fullname: Gilbert
– volume: 33
  start-page: 76
  year: 2014
  ident: 10.1016/j.tibs.2017.06.002_bib0160
  article-title: The mechanism of translation initiation on type 1 picornavirus IRESs
  publication-title: EMBO J.
  doi: 10.1002/embj.201386124
  contributor:
    fullname: Sweeney
– volume: 6
  start-page: 37319
  year: 2016
  ident: 10.1016/j.tibs.2017.06.002_bib0195
  article-title: Molecular analysis of the factorless internal ribosome entry site in cricket paralysis virus infection
  publication-title: Sci. Rep.
  doi: 10.1038/srep37319
  contributor:
    fullname: Kerr
– volume: 109
  start-page: E630
  year: 2012
  ident: 10.1016/j.tibs.2017.06.002_bib0495
  article-title: Alternative reading frame selection mediated by a tRNA-like domain of an internal ribosome entry site
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  doi: 10.1073/pnas.1111303109
  contributor:
    fullname: Ren
– volume: 44
  start-page: 214
  year: 2011
  ident: 10.1016/j.tibs.2017.06.002_bib0440
  article-title: Structure and dynamics of the mammalian ribosomal pretranslocation complex
  publication-title: Mol. Cell
  doi: 10.1016/j.molcel.2011.07.040
  contributor:
    fullname: Budkevich
– volume: 430
  start-page: 333
  year: 2007
  ident: 10.1016/j.tibs.2017.06.002_bib0215
  article-title: Structural methods for studying IRES function
  publication-title: Methods Enzymol.
  doi: 10.1016/S0076-6879(07)30013-X
  contributor:
    fullname: Kieft
– volume: 86
  start-page: 1468
  year: 2012
  ident: 10.1016/j.tibs.2017.06.002_bib0205
  article-title: A distinct class of internal ribosomal entry site in members of the Kobuvirus and proposed Salivirus and Paraturdivirus genera of the Picornaviridae
  publication-title: J. Virol.
  doi: 10.1128/JVI.05862-11
  contributor:
    fullname: Sweeney
– volume: 403
  start-page: 332
  year: 2000
  ident: 10.1016/j.tibs.2017.06.002_bib0600
  article-title: The joining of ribosomal subunits in eukaryotes requires eIF5B
  publication-title: Nature
  doi: 10.1038/35002118
  contributor:
    fullname: Pestova
– volume: 57
  start-page: 422
  year: 2015
  ident: 10.1016/j.tibs.2017.06.002_bib0480
  article-title: Cryo-EM of ribosomal 80S complexes with termination factors reveals the translocated cricket paralysis virus IRES
  publication-title: Mol. Cell
  doi: 10.1016/j.molcel.2014.12.016
  contributor:
    fullname: Muhs
– volume: 281
  start-page: 3685
  year: 2014
  ident: 10.1016/j.tibs.2017.06.002_bib0520
  article-title: Magnesium-dependent folding of a picornavirus IRES element modulates RNA conformation and eIF4G interaction
  publication-title: FEBS J.
  doi: 10.1111/febs.12890
  contributor:
    fullname: Lozano
– volume: 2
  start-page: 867
  year: 1996
  ident: 10.1016/j.tibs.2017.06.002_bib0140
  article-title: Internal initiation of translation of hepatitis C virus RNA: the ribosome entry site is at the authentic initiation codon
  publication-title: RNA
  contributor:
    fullname: Reynolds
– volume: 106
  start-page: 9197
  year: 2009
  ident: 10.1016/j.tibs.2017.06.002_bib0525
  article-title: Direct functional interaction of initiation factor eIF4G with type 1 internal ribosomal entry sites
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  doi: 10.1073/pnas.0900153106
  contributor:
    fullname: de Breyne
– volume: 111
  start-page: 15385
  year: 2014
  ident: 10.1016/j.tibs.2017.06.002_bib0175
  article-title: Base pairing between hepatitis C virus RNA and 18S rRNA is required for IRES-dependent translation initiation in vivo
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  doi: 10.1073/pnas.1413472111
  contributor:
    fullname: Matsuda
– volume: 10
  start-page: 1033
  year: 2003
  ident: 10.1016/j.tibs.2017.06.002_bib0220
  article-title: Structure of HCV IRES domain II determined by NMR
  publication-title: Nat. Struct. Biol.
  doi: 10.1038/nsb1004
  contributor:
    fullname: Lukavsky
– volume: 6
  start-page: 513
  year: 2009
  ident: 10.1016/j.tibs.2017.06.002_bib0100
  article-title: Hepatitis C virus blocks interferon effector function by inducing protein kinase R phosphorylation
  publication-title: Cell Host Microbe
  doi: 10.1016/j.chom.2009.11.004
  contributor:
    fullname: Garaigorta
– volume: 83
  start-page: 779
  year: 2014
  ident: 10.1016/j.tibs.2017.06.002_bib0015
  article-title: The scanning mechanism of eukaryotic translation initiation
  publication-title: Annu. Rev. Biochem.
  doi: 10.1146/annurev-biochem-060713-035802
  contributor:
    fullname: Hinnebusch
– volume: 25
  start-page: 10556
  year: 2005
  ident: 10.1016/j.tibs.2017.06.002_bib0090
  article-title: Eukaryotic translation initiation factor 4E availability controls the switch between cap-dependent and internal ribosomal entry site-mediated translation
  publication-title: Mol. Cell Biol.
  doi: 10.1128/MCB.25.23.10556-10565.2005
  contributor:
    fullname: Svitkin
– volume: 282
  start-page: 7770
  year: 2007
  ident: 10.1016/j.tibs.2017.06.002_bib0435
  article-title: Binding mode of the first aminoacyl-tRNA in translation initiation mediated by Plautia stali intestine virus internal ribosome entry site
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M610887200
  contributor:
    fullname: Yamamoto
– volume: 12
  start-page: 67
  year: 1998
  ident: 10.1016/j.tibs.2017.06.002_bib0150
  article-title: A prokaryotic-like mode of cytoplasmic eukaryotic ribosome binding to the initiation codon during internal translation initiation of hepatitis C and classical swine fever virus RNAs
  publication-title: Genes Dev.
  doi: 10.1101/gad.12.1.67
  contributor:
    fullname: Pestova
– volume: 25
  start-page: 320
  year: 2015
  ident: 10.1016/j.tibs.2017.06.002_bib0255
  article-title: To translate, or not to translate: viral and host mRNA regulation by interferon-stimulated genes
  publication-title: Trends Cell Biol.
  doi: 10.1016/j.tcb.2015.02.001
  contributor:
    fullname: Li
– volume: 157
  start-page: 823
  year: 2014
  ident: 10.1016/j.tibs.2017.06.002_bib0165
  article-title: Initiation of translation by cricket paralysis virus IRES requires its translocation in the ribosome
  publication-title: Cell
  doi: 10.1016/j.cell.2014.04.015
  contributor:
    fullname: Fernandez
– volume: 334
  start-page: 320
  year: 1988
  ident: 10.1016/j.tibs.2017.06.002_bib0060
  article-title: Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA
  publication-title: Nature
  doi: 10.1038/334320a0
  contributor:
    fullname: Pelletier
– volume: 3
  start-page: 283
  year: 2016
  ident: 10.1016/j.tibs.2017.06.002_bib0065
  article-title: A cap-to-tail guide to mRNA translation strategies in virus-infected cells
  publication-title: Annu. Rev. Virol.
  doi: 10.1146/annurev-virology-100114-055014
  contributor:
    fullname: Jan
– volume: 159
  start-page: 1086
  year: 2014
  ident: 10.1016/j.tibs.2017.06.002_bib0375
  article-title: RACK1 controls IRES-mediated translation of viruses
  publication-title: Cell
  doi: 10.1016/j.cell.2014.10.041
  contributor:
    fullname: Majzoub
– volume: 13
  start-page: 1092
  year: 2006
  ident: 10.1016/j.tibs.2017.06.002_bib0400
  article-title: Structure of the ribosome-bound cricket paralysis virus IRES RNA
  publication-title: Nat. Struct. Mol. Biol.
  doi: 10.1038/nsmb1177
  contributor:
    fullname: Schuler
– volume: 24
  start-page: 1787
  year: 2010
  ident: 10.1016/j.tibs.2017.06.002_bib0265
  article-title: Activities of Ligatin and MCT-1/DENR in eukaryotic translation initiation and ribosomal recycling
  publication-title: Genes Dev.
  doi: 10.1101/gad.1957510
  contributor:
    fullname: Skabkin
– volume: 19
  start-page: 1456
  year: 2011
  ident: 10.1016/j.tibs.2017.06.002_bib0300
  article-title: Crystal structure of the HCV IRES central domain reveals strategy for start-codon positioning
  publication-title: Structure
  doi: 10.1016/j.str.2011.08.002
  contributor:
    fullname: Berry
– volume: 118
  start-page: 465
  year: 2004
  ident: 10.1016/j.tibs.2017.06.002_bib0505
  article-title: Cryo-EM visualization of a viral internal ribosome entry site bound to human ribosomes: the IRES functions as an RNA-based translation factor
  publication-title: Cell
  doi: 10.1016/j.cell.2004.08.001
  contributor:
    fullname: Spahn
– volume: 478
  start-page: 61
  year: 2015
  ident: 10.1016/j.tibs.2017.06.002_bib0240
  article-title: Widespread distribution and structural diversity of type IV IRESs in members of Picornaviridae
  publication-title: Virology
  doi: 10.1016/j.virol.2015.02.016
  contributor:
    fullname: Asnani
– volume: 5
  start-page: e21198
  year: 2016
  ident: 10.1016/j.tibs.2017.06.002_bib0250
  article-title: Translation initiation by the hepatitis C virus IRES requires eIF1A and ribosomal complex remodeling
  publication-title: Elife
  doi: 10.7554/eLife.21198
  contributor:
    fullname: Jaafar
– volume: 161
  start-page: 845
  year: 2015
  ident: 10.1016/j.tibs.2017.06.002_bib0450
  article-title: Structural snapshots of actively translating human ribosomes
  publication-title: Cell
  doi: 10.1016/j.cell.2015.03.052
  contributor:
    fullname: Behrmann
– volume: 59
  start-page: 399
  year: 2015
  ident: 10.1016/j.tibs.2017.06.002_bib0335
  article-title: Conformational differences between open and closed states of the eukaryotic translation initiation complex
  publication-title: Mol. Cell
  doi: 10.1016/j.molcel.2015.06.033
  contributor:
    fullname: Llacer
– volume: 345
  start-page: 1188
  year: 2014
  ident: 10.1016/j.tibs.2017.06.002_bib0475
  article-title: How the ribosome hands the A-site tRNA to the P site during EF-G-catalyzed translocation
  publication-title: Science
  doi: 10.1126/science.1255030
  contributor:
    fullname: Zhou
– volume: 73
  start-page: 3467
  year: 1999
  ident: 10.1016/j.tibs.2017.06.002_bib0110
  article-title: Eukaryotic initiation factor 4GII (eIF4GII), but not eIF4GI, cleavage correlates with inhibition of host cell protein synthesis after human rhinovirus infection
  publication-title: J. Virol.
  doi: 10.1128/JVI.73.4.3467-3472.1999
  contributor:
    fullname: Svitkin
– volume: 8
  start-page: 913
  year: 2002
  ident: 10.1016/j.tibs.2017.06.002_bib0295
  article-title: Ribosomal proteins mediate the hepatitis C virus IRES–HeLa 40S interaction
  publication-title: RNA
  doi: 10.1017/S1355838202022057
  contributor:
    fullname: Otto
– volume: 15
  start-page: 1109
  year: 1978
  ident: 10.1016/j.tibs.2017.06.002_bib0020
  article-title: How do eucaryotic ribosomes select initiation regions in messenger RNA?
  publication-title: Cell
  doi: 10.1016/0092-8674(78)90039-9
  contributor:
    fullname: Kozak
– volume: 23
  start-page: 859
  year: 2016
  ident: 10.1016/j.tibs.2017.06.002_bib0535
  article-title: An accurately preorganized IRES RNA structure enables eIF4G capture for initiation of viral translation
  publication-title: Nat. Struct. Mol. Biol.
  doi: 10.1038/nsmb.3280
  contributor:
    fullname: Imai
– volume: 97
  start-page: 1512
  year: 2000
  ident: 10.1016/j.tibs.2017.06.002_bib0405
  article-title: Methionine-independent initiation of translation in the capsid protein of an insect RNA virus
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  doi: 10.1073/pnas.010426997
  contributor:
    fullname: Sasaki
– volume: 351
  start-page: aad4939
  year: 2016
  ident: 10.1016/j.tibs.2017.06.002_bib0570
  article-title: Systematic discovery of cap-independent translation sequences in human and viral genomes
  publication-title: Science
  doi: 10.1126/science.aad4939
  contributor:
    fullname: Weingarten-Gabbay
– volume: 139
  start-page: 166
  year: 2009
  ident: 10.1016/j.tibs.2017.06.002_bib0235
  article-title: Structure and function of HCV IRES domains
  publication-title: Virus Res.
  doi: 10.1016/j.virusres.2008.06.004
  contributor:
    fullname: Lukavsky
– volume: 12
  start-page: 894
  year: 2006
  ident: 10.1016/j.tibs.2017.06.002_bib0275
  article-title: Initiation factor-independent translation mediated by the hepatitis C virus internal ribosome entry site
  publication-title: RNA
  doi: 10.1261/rna.2342306
  contributor:
    fullname: Lancaster
– volume: 111
  start-page: 15952
  year: 2014
  ident: 10.1016/j.tibs.2017.06.002_bib0320
  article-title: Functional conservation despite structural divergence in ligand-responsive RNA switches
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  doi: 10.1073/pnas.1414678111
  contributor:
    fullname: Boerneke
– volume: 206
  start-page: 62
  year: 2015
  ident: 10.1016/j.tibs.2017.06.002_bib0510
  article-title: Picornavirus IRES elements: RNA structure and host protein interactions
  publication-title: Virus Res.
  doi: 10.1016/j.virusres.2015.01.012
  contributor:
    fullname: Martinez-Salas
– volume: 86
  start-page: 10686
  year: 2012
  ident: 10.1016/j.tibs.2017.06.002_bib0080
  article-title: Site-specific cleavage of the host poly(A) binding protein by the encephalomyocarditis virus 3C proteinase stimulates viral replication
  publication-title: J. Virol.
  doi: 10.1128/JVI.00896-12
  contributor:
    fullname: Kobayashi
– volume: 503
  start-page: 539
  year: 2013
  ident: 10.1016/j.tibs.2017.06.002_bib0360
  article-title: Hepatitis-C-virus-like internal ribosome entry sites displace eIF3 to gain access to the 40S subunit
  publication-title: Nature
  doi: 10.1038/nature12658
  contributor:
    fullname: Hashem
– volume: 31
  start-page: 2434
  year: 2003
  ident: 10.1016/j.tibs.2017.06.002_bib0395
  article-title: Structural elements in the internal ribosome entry site of Plautia stali intestine virus responsible for binding with ribosomes
  publication-title: Nucleic Acids Res.
  doi: 10.1093/nar/gkg336
  contributor:
    fullname: Nishiyama
– volume: 280
  start-page: 82
  year: 1979
  ident: 10.1016/j.tibs.2017.06.002_bib0180
  article-title: Inability of circular mRNA to attach to eukaryotic ribosomes
  publication-title: Nature
  doi: 10.1038/280082a0
  contributor:
    fullname: Kozak
– volume: 26
  start-page: 41
  year: 2007
  ident: 10.1016/j.tibs.2017.06.002_bib0340
  article-title: The eukaryotic translation initiation factors eIF1 and eIF1A induce an open conformation of the 40S ribosome
  publication-title: Mol. Cell
  doi: 10.1016/j.molcel.2007.03.018
  contributor:
    fullname: Passmore
– volume: 68
  start-page: 119
  year: 1992
  ident: 10.1016/j.tibs.2017.06.002_bib0190
  article-title: Prokaryotic-like cis elements in the cap-independent internal initiation of translation on picornavirus RNA
  publication-title: Cell
  doi: 10.1016/0092-8674(92)90211-T
  contributor:
    fullname: Pilipenko
– volume: 30
  start-page: 1573
  year: 2016
  ident: 10.1016/j.tibs.2017.06.002_bib0585
  article-title: Toward the mechanism of eIF4F-mediated ribosomal attachment to mammalian capped mRNAs
  publication-title: Genes Dev.
  doi: 10.1101/gad.282418.116
  contributor:
    fullname: Kumar
– volume: 42
  start-page: 12052
  year: 2014
  ident: 10.1016/j.tibs.2017.06.002_bib0605
  article-title: EIF5 and eIF5B together stimulate 48S initiation complex formation during ribosomal scanning
  publication-title: Nucleic Acids Res.
  doi: 10.1093/nar/gku877
  contributor:
    fullname: Pisareva
– volume: 23
  start-page: 687
  year: 2003
  ident: 10.1016/j.tibs.2017.06.002_bib0545
  article-title: Eukaryotic initiation factors 4G and 4A mediate conformational changes downstream of the initiation codon of the encephalomyocarditis virus internal ribosomal entry site
  publication-title: Mol. Cell. Biol.
  doi: 10.1128/MCB.23.2.687-698.2003
  contributor:
    fullname: Kolupaeva
– volume: 5
  start-page: e13567
  year: 2016
  ident: 10.1016/j.tibs.2017.06.002_bib0455
  article-title: Structural characterization of ribosome recruitment and translocation by type IV IRES
  publication-title: Elife
  doi: 10.7554/eLife.13567
  contributor:
    fullname: Murray
– volume: 145
  start-page: 383
  year: 2011
  ident: 10.1016/j.tibs.2017.06.002_bib0580
  article-title: Ribosome-mediated specificity in Hox mRNA translation and vertebrate tissue patterning
  publication-title: Cell
  doi: 10.1016/j.cell.2011.03.028
  contributor:
    fullname: Kondrashov
– volume: 39
  start-page: 4851
  year: 2011
  ident: 10.1016/j.tibs.2017.06.002_bib0530
  article-title: Common conformational changes induced in type 2 picornavirus IRESs by cognate trans-acting factors
  publication-title: Nucleic Acids Res.
  doi: 10.1093/nar/gkr045
  contributor:
    fullname: Yu
– volume: 34
  start-page: 556
  year: 2009
  ident: 10.1016/j.tibs.2017.06.002_bib0555
  article-title: Polypyrimidine tract binding protein stabilizes the encephalomyocarditis virus IRES structure via binding multiple sites in a unique orientation
  publication-title: Mol. Cell
  doi: 10.1016/j.molcel.2009.04.015
  contributor:
    fullname: Kafasla
– volume: 324
  start-page: 889
  year: 2002
  ident: 10.1016/j.tibs.2017.06.002_bib0390
  article-title: Factorless ribosome assembly on the internal ribosome entry site of cricket paralysis virus
  publication-title: J. Mol. Biol.
  doi: 10.1016/S0022-2836(02)01099-9
  contributor:
    fullname: Jan
– volume: 5
  start-page: a011569
  year: 2013
  ident: 10.1016/j.tibs.2017.06.002_bib0050
  article-title: The current status of vertebrate cellular mRNA IRESs
  publication-title: Cold Spring Harb. Perspect. Biol.
  doi: 10.1101/cshperspect.a011569
  contributor:
    fullname: Jackson
– volume: 16
  start-page: 6870
  year: 1996
  ident: 10.1016/j.tibs.2017.06.002_bib0515
  article-title: Functional dissection of eukaryotic initiation factor 4F: the 4A subunit and the central domain of the 4G subunit are sufficient to mediate internal entry of 43S preinitiation complexes
  publication-title: Mol. Cell. Biol.
  doi: 10.1128/MCB.16.12.6870
  contributor:
    fullname: Pestova
– volume: 16
  start-page: 2906
  year: 2002
  ident: 10.1016/j.tibs.2017.06.002_bib0590
  article-title: The roles of individual eukaryotic translation initiation factors in ribosomal scanning and initiation codon selection
  publication-title: Genes Dev.
  doi: 10.1101/gad.1020902
  contributor:
    fullname: Pestova
– volume: 17
  start-page: 4632
  year: 2006
  ident: 10.1016/j.tibs.2017.06.002_bib0115
  article-title: Initiation of protein synthesis by hepatitis C virus is refractory to reduced eIF2*GTP*Met-tRNAiMet ternary complex availability
  publication-title: Mol. Biol. Cell
  doi: 10.1091/mbc.e06-06-0478
  contributor:
    fullname: Robert
– volume: 525
  start-page: 491
  year: 2015
  ident: 10.1016/j.tibs.2017.06.002_bib0330
  article-title: Structure of mammalian eIF3 in the context of the 43S preinitiation complex
  publication-title: Nature
  doi: 10.1038/nature14891
  contributor:
    fullname: des Georges
– volume: 30
  start-page: 2454
  year: 2011
  ident: 10.1016/j.tibs.2017.06.002_bib0270
  article-title: eIF2A mediates translation of hepatitis C viral mRNA under stress conditions
  publication-title: EMBO J.
  doi: 10.1038/emboj.2011.146
  contributor:
    fullname: Kim
– volume: 110
  start-page: 20964
  year: 2013
  ident: 10.1016/j.tibs.2017.06.002_bib0470
  article-title: Visualization of two transfer RNAs trapped in transit during elongation factor G-mediated translocation
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  doi: 10.1073/pnas.1320387110
  contributor:
    fullname: Ramrath
– volume: 39
  start-page: 5264
  year: 2011
  ident: 10.1016/j.tibs.2017.06.002_bib0425
  article-title: Structural basis for the binding of IRES RNAs to the head of the ribosomal 40S subunit
  publication-title: Nucleic Acids Res.
  doi: 10.1093/nar/gkr114
  contributor:
    fullname: Muhs
– volume: 34
  start-page: 3042
  year: 2015
  ident: 10.1016/j.tibs.2017.06.002_bib0280
  article-title: Molecular architecture of the ribosome-bound hepatitis C virus internal ribosomal entry site RNA
  publication-title: EMBO J.
  doi: 10.15252/embj.201592469
  contributor:
    fullname: Yamamoto
– volume: 7
  start-page: 194
  year: 2001
  ident: 10.1016/j.tibs.2017.06.002_bib0610
  article-title: Mechanism of ribosome recruitment by hepatitis C IRES RNA
  publication-title: RNA
  doi: 10.1017/S1355838201001790
  contributor:
    fullname: Kieft
– volume: 49
  start-page: 164
  year: 2014
  ident: 10.1016/j.tibs.2017.06.002_bib0035
  article-title: Transcriptome-wide studies uncover the diversity of modes of mRNA recruitment to eukaryotic ribosomes
  publication-title: Crit. Rev. Biochem. Mol. Biol.
  doi: 10.3109/10409238.2014.887051
  contributor:
    fullname: Shatsky
– volume: 15
  start-page: 836
  year: 2008
  ident: 10.1016/j.tibs.2017.06.002_bib0260
  article-title: Eukaryotic translation initiation machinery can operate in a bacterial-like mode without eIF2
  publication-title: Nat. Struct. Mol. Biol.
  doi: 10.1038/nsmb.1445
  contributor:
    fullname: Terenin
– volume: 33
  start-page: 1016
  year: 2013
  ident: 10.1016/j.tibs.2017.06.002_bib0560
  article-title: Ribosomal protein S25 dependency reveals a common mechanism for diverse internal ribosome entry sites and ribosome shunting
  publication-title: Mol. Cell. Biol.
  doi: 10.1128/MCB.00879-12
  contributor:
    fullname: Hertz
– volume: 535
  start-page: 570
  year: 2016
  ident: 10.1016/j.tibs.2017.06.002_bib0025
  article-title: Dynamics of ribosome scanning and recycling revealed by translation complex profiling
  publication-title: Nature
  doi: 10.1038/nature18647
  contributor:
    fullname: Archer
– volume: 5
  start-page: e13429
  year: 2016
  ident: 10.1016/j.tibs.2017.06.002_bib0485
  article-title: Kinetics of initiating polypeptide elongation in an IRES-dependent system
  publication-title: Elife
  doi: 10.7554/eLife.13429
  contributor:
    fullname: Zhang
– volume: 111
  start-page: 9139
  year: 2014
  ident: 10.1016/j.tibs.2017.06.002_bib0415
  article-title: Taura syndrome virus IRES initiates translation by binding its tRNA-mRNA-like structural element in the ribosomal decoding center
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  doi: 10.1073/pnas.1406335111
  contributor:
    fullname: Koh
– volume: 22
  start-page: 1210
  year: 2014
  ident: 10.1016/j.tibs.2017.06.002_bib0445
  article-title: Structures of yeast 80S ribosome-tRNA complexes in the rotated and nonrotated conformations
  publication-title: Structure
  doi: 10.1016/j.str.2014.06.003
  contributor:
    fullname: Svidritskiy
– volume: 62
  start-page: 92
  year: 2016
  ident: 10.1016/j.tibs.2017.06.002_bib0490
  article-title: Multiple parallel pathways of translation initiation on the CrPV IRES
  publication-title: Mol. Cell
  doi: 10.1016/j.molcel.2016.03.020
  contributor:
    fullname: Petrov
– volume: 163
  start-page: 999
  year: 2015
  ident: 10.1016/j.tibs.2017.06.002_bib0045
  article-title: 5′ UTR m6A promotes cap-undependent translation
  publication-title: Cell
  doi: 10.1016/j.cell.2015.10.012
  contributor:
    fullname: Meyer
– volume: 468
  start-page: 713
  year: 2010
  ident: 10.1016/j.tibs.2017.06.002_bib0465
  article-title: Head swivel on the ribosome facilitates translocation by means of intra-subunit tRNA hybrid sites
  publication-title: Nature
  doi: 10.1038/nature09547
  contributor:
    fullname: Ratje
– volume: 95
  start-page: 11089
  year: 1998
  ident: 10.1016/j.tibs.2017.06.002_bib0070
  article-title: Proteolysis of human eukaryotic translation initiation factor eIF4GII, but not eIF4GI, coincides with the shutoff of host protein synthesis after poliovirus infection
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  doi: 10.1073/pnas.95.19.11089
  contributor:
    fullname: Gradi
– volume: 16
  start-page: 397
  year: 2009
  ident: 10.1016/j.tibs.2017.06.002_bib0370
  article-title: The pathway of hepatitis C virus mRNA recruitment to the human ribosome
  publication-title: Nat. Struct. Mol. Biol.
  doi: 10.1038/nsmb.1572
  contributor:
    fullname: Fraser
– volume: 517
  start-page: 33
  year: 2015
  ident: 10.1016/j.tibs.2017.06.002_bib0575
  article-title: RNA regulons in Hox 5′ UTRs confer ribosome specificity to gene regulation
  publication-title: Nature
  doi: 10.1038/nature14010
  contributor:
    fullname: Xue
– volume: 536
  start-page: 96
  year: 2016
  ident: 10.1016/j.tibs.2017.06.002_bib0040
  article-title: eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation
  publication-title: Nature
  doi: 10.1038/nature18954
  contributor:
    fullname: Lee
– volume: 78
  start-page: 53
  year: 2013
  ident: 10.1016/j.tibs.2017.06.002_bib0290
  article-title: Proteins of the human 40S ribosomal subunit involved in hepatitis C IRES binding as revealed from fluorescent labeling
  publication-title: Biochemistry (Mosc.)
  doi: 10.1134/S0006297913010069
  contributor:
    fullname: Malygin
– volume: 112
  start-page: 319
  year: 2015
  ident: 10.1016/j.tibs.2017.06.002_bib0350
  article-title: Kinetic pathway of 40S ribosomal subunit recruitment to hepatitis C virus internal ribosome entry site
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  doi: 10.1073/pnas.1421328111
  contributor:
    fullname: Fuchs
– volume: 15
  start-page: 57
  year: 2008
  ident: 10.1016/j.tibs.2017.06.002_bib0430
  article-title: tRNA-mRNA mimicry drives translation initiation from a viral IRES
  publication-title: Nat. Struct. Mol. Biol.
  doi: 10.1038/nsmb1351
  contributor:
    fullname: Costantino
– volume: 364
  start-page: 466
  year: 2007
  ident: 10.1016/j.tibs.2017.06.002_bib0085
  article-title: Foot-and-mouth disease virus infection induces proteolytic cleavage of PTB, eIF3a,b, and PABP RNA-binding proteins
  publication-title: Virology
  doi: 10.1016/j.virol.2007.03.013
  contributor:
    fullname: Rodriguez Pulido
– volume: 84
  start-page: 1124
  year: 2010
  ident: 10.1016/j.tibs.2017.06.002_bib0095
  article-title: Host and viral translational mechanisms during cricket paralysis virus infection
  publication-title: J. Virol.
  doi: 10.1128/JVI.02006-09
  contributor:
    fullname: Garrey
– volume: 283
  start-page: 2508
  year: 2016
  ident: 10.1016/j.tibs.2017.06.002_bib0565
  article-title: Structural domains within the HIV-1 mRNA and the ribosomal protein S25 influence cap-independent translation initiation
  publication-title: FEBS J.
  doi: 10.1111/febs.13756
  contributor:
    fullname: Carvajal
– volume: 486
  start-page: 126
  year: 2012
  ident: 10.1016/j.tibs.2017.06.002_bib0030
  article-title: An oxygen-regulated switch in the protein synthesis machinery
  publication-title: Nature
  doi: 10.1038/nature11055
  contributor:
    fullname: Uniacke
– volume: 12
  start-page: 862
  year: 2016
  ident: 10.1016/j.tibs.2017.06.002_bib0010
  article-title: Transcriptomics resources of human tissues and organs
  publication-title: Mol. Syst. Biol.
  doi: 10.15252/msb.20155865
  contributor:
    fullname: Uhlen
– volume: 7
  start-page: 266
  year: 2001
  ident: 10.1016/j.tibs.2017.06.002_bib0380
  article-title: A tertiary structure model of the internal ribosome entry site (IRES) for methionine-independent initiation of translation
  publication-title: RNA
  doi: 10.1017/S1355838201001741
  contributor:
    fullname: Kanamori
– volume: 23
  start-page: 2753
  year: 2009
  ident: 10.1016/j.tibs.2017.06.002_bib0420
  article-title: RPS25 is essential for translation initiation by the Dicistroviridae and hepatitis C viral IRESs
  publication-title: Genes Dev.
  doi: 10.1101/gad.1832209
  contributor:
    fullname: Landry
– volume: 27
  start-page: 1060
  year: 2008
  ident: 10.1016/j.tibs.2017.06.002_bib0245
  article-title: eIF2-dependent and eIF2-independent modes of initiation on the CSFV IRES: a common role of domain II
  publication-title: EMBO J.
  doi: 10.1038/emboj.2008.49
  contributor:
    fullname: Pestova
– volume: 6
  start-page: 7646
  year: 2015
  ident: 10.1016/j.tibs.2017.06.002_bib0285
  article-title: Cryo-EM structure of hepatitis C virus IRES bound to the human ribosome at 3.9-Å resolution
  publication-title: Nat. Commun.
  doi: 10.1038/ncomms8646
  contributor:
    fullname: Quade
– volume: 42
  start-page: 10373
  year: 2014
  ident: 10.1016/j.tibs.2017.06.002_bib0550
  article-title: 40S recruitment in the absence of eIF4G/4A by EMCV IRES refines the model for translation initiation on the archetype of type II IRESs
  publication-title: Nucleic Acids Res.
  doi: 10.1093/nar/gku720
  contributor:
    fullname: Chamond
– volume: 5
  start-page: e14874
  year: 2016
  ident: 10.1016/j.tibs.2017.06.002_bib0460
  article-title: Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome
  publication-title: Elife
  doi: 10.7554/eLife.14874
  contributor:
    fullname: Abeyrathne
– volume: 4
  start-page: 1612
  year: 2013
  ident: 10.1016/j.tibs.2017.06.002_bib0225
  article-title: Structure of the full-length HCV IRES in solution
  publication-title: Nat. Commun.
  doi: 10.1038/ncomms2611
  contributor:
    fullname: Perard
– volume: 62
  start-page: 2636
  year: 1988
  ident: 10.1016/j.tibs.2017.06.002_bib0055
  article-title: A segment of the 5′ nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation
  publication-title: J. Virol.
  doi: 10.1128/JVI.62.8.2636-2643.1988
  contributor:
    fullname: Jang
– volume: 430
  start-page: 409
  year: 2007
  ident: 10.1016/j.tibs.2017.06.002_bib0210
  article-title: In vitro reconstitution and biochemical characterization of translation initiation by internal ribosomal entry
  publication-title: Methods Enzymol.
  doi: 10.1016/S0076-6879(07)30016-5
  contributor:
    fullname: Kolupaeva
– volume: 71
  start-page: 1342
  year: 1974
  ident: 10.1016/j.tibs.2017.06.002_bib0500
  article-title: The 3′ terminal sequence of E:coli 16S ribosomal RNA: complementarity to nonsense triplets and ribosome binding sites
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  doi: 10.1073/pnas.71.4.1342
  contributor:
    fullname: Shine
– volume: 5
  start-page: 823
  year: 2009
  ident: 10.1016/j.tibs.2017.06.002_bib0315
  article-title: Conformational inhibition of the hepatitis C virus internal ribosome entry site RNA
  publication-title: Nat. Chem. Biol.
  doi: 10.1038/nchembio.217
  contributor:
    fullname: Parsons
– volume: 291
  start-page: 1959
  year: 2001
  ident: 10.1016/j.tibs.2017.06.002_bib0325
  article-title: Hepatitis C virus IRES RNA-induced changes in the conformation of the 40s ribosomal subunit
  publication-title: Science
  doi: 10.1126/science.1058409
  contributor:
    fullname: Spahn
– volume: 121
  start-page: 228
  year: 2016
  ident: 10.1016/j.tibs.2017.06.002_bib0135
  article-title: Does HIV-1 mRNA 5′-untranslated region bear an internal ribosome entry site?
  publication-title: Biochimie
  doi: 10.1016/j.biochi.2015.12.004
  contributor:
    fullname: Smirnova
– volume: 20
  start-page: 150
  year: 2013
  ident: 10.1016/j.tibs.2017.06.002_bib0310
  article-title: HCV IRES manipulates the ribosome to promote the switch from translation initiation to elongation
  publication-title: Nat. Struct. Mol. Biol.
  doi: 10.1038/nsmb.2465
  contributor:
    fullname: Filbin
– volume: 6
  start-page: 24243
  year: 2016
  ident: 10.1016/j.tibs.2017.06.002_bib0540
  article-title: Designing synthetic RNAs to determine the relevance of structural motifs in picornavirus IRES elements
  publication-title: Sci. Rep.
  doi: 10.1038/srep24243
  contributor:
    fullname: Fernandez-Chamorro
– volume: 72
  start-page: 4775
  year: 1998
  ident: 10.1016/j.tibs.2017.06.002_bib0365
  article-title: Specific interaction of eukaryotic translation initiation factor 3 with the 5′ nontranslated regions of hepatitis C virus and classical swine fever virus RNAs
  publication-title: J. Virol.
  doi: 10.1128/JVI.72.6.4775-4782.1998
  contributor:
    fullname: Sizova
– volume: 81
  start-page: 5850
  year: 2007
  ident: 10.1016/j.tibs.2017.06.002_bib0200
  article-title: A distinct group of hepacivirus/pestivirus-like internal ribosomal entry sites in members of diverse picornavirus genera: evidence for modular exchange of functional noncoding RNA elements by recombination
  publication-title: J. Virol.
  doi: 10.1128/JVI.02403-06
  contributor:
    fullname: Hellen
– volume: 20
  start-page: 4233
  year: 2001
  ident: 10.1016/j.tibs.2017.06.002_bib0105
  article-title: Truncated initiation factor eIF4G lacking an eIF4E binding site can support capped mRNA translation
  publication-title: EMBO J.
  doi: 10.1093/emboj/20.15.4233
  contributor:
    fullname: Ali
– volume: 102
  start-page: 511
  year: 2000
  ident: 10.1016/j.tibs.2017.06.002_bib0410
  article-title: Initiation of protein synthesis from the A site of the ribosome
  publication-title: Cell
  doi: 10.1016/S0092-8674(00)00055-6
  contributor:
    fullname: Wilson
SSID ssj0015775
Score 2.5164597
SecondaryResourceType review_article
Snippet Internal initiation is a 5′-end-independent mode of translation initiation engaged by many virus- and putatively some cell-encoded templates. Internal...
Internal initiation is a 5'-end-independent mode of translation initiation engaged by many virus- and putatively some cell-encoded templates. Internal...
SourceID proquest
crossref
pubmed
elsevier
SourceType Aggregation Database
Index Database
Publisher
StartPage 655
SubjectTerms 5' Untranslated Regions - genetics
eukaryotic translation initiation
internal ribosome entry site
Internal Ribosome Entry Sites - genetics
Nucleic Acid Conformation
ribosome
Ribosomes - chemistry
Ribosomes - genetics
Ribosomes - metabolism
Title Ribosomal Chamber Music: Toward an Understanding of IRES Mechanisms
URI https://dx.doi.org/10.1016/j.tibs.2017.06.002
https://www.ncbi.nlm.nih.gov/pubmed/28684008
https://search.proquest.com/docview/1917361532
Volume 42
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1LS8NAEF5qi-BFfFsfZQVvEptk89h4K8XSKu1BW-htyW52MUKTYtODF3-7O5ukKKgHjwm7ZJkZZr7NzHyD0LW-23BIz1iEKmlpo4gsTmyhnSEJZSI8mhiegvEkGM68h7k_b6B-3QsDZZWV7y99uvHW1ZtuJc3uMk27zxp8U4AkDhipDe3XLR2OIFfb6o0eh5NNMsEPDd8urDdN1FXvTFnmVaQcWLud0NB4Vn9XfohPv-FPE4cGe2i3ApC4V55xHzVkdoC2y5GS74eo_5TyfJUv9JL-SwzTPrAZ5XyHp6ZAFscZnn1taMG5wiOtBjyW0AScrharIzQb3E_7Q6salGAJz3ULy-MBlVSIQLo8tH1BI09pmEIcR8Yhl64SKiBCOkC45XFFAVaHxEkSESSRCiJyjJpZnslThLkvhVKSRMTWyESjRxXFgRtTyeGqGPM2uqnFw5YlHwarC8VeGQiTgTCZqZZz28ivJci-aZVph_3nvqta3EybO-Qw4kzm6xWD6yUBkKrXnJR62JzDpcBcY9Ozf371HO3AU1ned4GaxdtaXmrIUfAO2rr9cDqVYX0CuXjSig
link.rule.ids 314,780,784,4502,24116,27924,27925,45585,45679
linkProvider Elsevier
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3NS8MwFA9jInoRv52fEbxJXdv0I_Umw7HptoNusFto0gQrrB12O3jxbzcvbYeCevDaJjS893j5pfm930PoSp9tOFzPWIQqaemgiCxObKGTIQllIjyaGJ2C4SjoTbyHqT9toE5dCwO0yir3lzndZOvqSbuyZnuepu1nDb4pQBIHgtSG8us1z9foVwf1zceK5-H4oVHbhdGmhLqqnClJXouUg2a3ExoRz-rfyg-702_o0-xC3W20VcFHfFeucAc1ZLaL1suGku97qPOU8rzIZ3pI5yWGXh_YNHK-xWNDj8Vxhidfy1lwrnBfOwEPJZQAp8Ws2EeT7v2407OqNgmW8Fx3YXk8oJIKEUiXh7YvaOQpDVKI48g45NJVQgVESAfktjyuKIDqkDhJIoIkUkFEDlAzyzN5hDD3pVBKkojYGpdo7KiiOHBjKjkcFGPeQte1edi8VMNgNU3slYExGRiTGa6c20J-bUH2zadMp-s_513W5mY62OEGI85kviwYHC4JQFQ95rD0w2odLgXdGpse__OrF2ijNx4O2KA_ejxBm_CmJPqdoubibSnPNPhY8HMTXJ-aAdNj
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Ribosomal+Chamber+Music%3A+Toward+an+Understanding+of+IRES+Mechanisms&rft.jtitle=Trends+in+biochemical+sciences+%28Amsterdam.+Regular+ed.%29&rft.au=Yamamoto%2C+Hiroshi&rft.au=Unbehaun%2C+Anett&rft.au=Spahn%2C+Christian+M+T&rft.date=2017-08-01&rft.issn=0968-0004&rft.volume=42&rft.issue=8&rft.spage=655&rft.epage=668&rft_id=info:doi/10.1016%2Fj.tibs.2017.06.002&rft.externalDBID=NO_FULL_TEXT
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0968-0004&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0968-0004&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0968-0004&client=summon