Association of COL2A1 Gene Polymorphism with Degenerative Lumbar Scoliosis

• Published in: Clinics in orthopedic surgery Vol. 6; no. 4; pp. 379 - 384
• Main Authors: Hwang, Dae Woo, Kim, Ki Tack, Lee, Sang Hoon, Kim, Jung Youn, Kim, Dong Hwan
• Format: Journal Article
• Language: English
• Published: Korea (South) The Korean Orthopaedic Association 01.12.2014; 대한정형외과학회
• Subjects: Aged; Asian Continental Ancestry Group; Collagen Type II - genetics; Female; Humans; Lumbar Vertebrae; Male; Middle Aged; Original; Polymorphism, Single Nucleotide; Scoliosis - ethnology; Scoliosis - genetics; 정형외과학; Korean; Degenerative lumbar scoliosis; COL2A1; Single nucleotide polymorphism

Degenerative lumbar scoliosis (DLS) progresses with aging after 50-60 years, and the genetic association of DLS remains largely unclear. In this study, the genetic association between collagen type II alpha 1 (COL2A1) gene and DLS was investigated. COL2A1 gene polymorphism was investigated in DLS su...