Pharmacokinetics and toxicokinetics of d-serine in rats - Hasegawa, Hiroshi; Masuda, Nami; Natori, Hiromi; Shinohara, Yoshihiko; Ichida, Kimiyoshi (Journal of pharmaceutical and biomedical analysis, 2019)
Keywords: Administration, Oral; Animals; Biomarkers - blood; Creatinine - blood; d-serine; Gas Chromatography-Mass Spectrometry; GC–MS; Injections, Intraperitoneal; Injections, Intravenous; Kidney - drug effects; Kidney - metabolism; Kidney - pathology; Kidney Diseases - blood; Kidney Diseases - chemically induced; Kidney Diseases - pathology; Male; Nephrotoxicity; Pharmacokinetics; Rats, Wistar; Serine - administration & dosage; Serine - blood; Serine - pharmacokinetics; Serine - toxicity; Stereoisomerism; Toxicokinetics; MTPA-Cl; CLtot; Fpo; tmax; AUCip; MRT; AUC; kel; bw; kabs; t1/2; AUC0-last; NMDA; Cmax; GC–MS; diMTPA-OMe; d-serine; ip; Fip; iv; Toxicokinetics; DAO; SIM; Pharmacokinetics; Nephrotoxicity; po