The plasma contact system as a modulator of innate immunity

• Published in: Current opinion in hematology Vol. 25; no. 5; p. 389
• Main Author: Wu, Yi
• Format: Journal Article
• Language: English
• Published: United States 01.09.2018

The contact system is a plasma protease cascade, which activates the proinflammatory kallikrein-kinin system and the procoagulant intrinsic coagulation pathway. Recent advances demonstrating the novel functions of this system as a key player of innate immune system will be introduced in the present...