Systematic Review for the 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines

• Published in: Circulation (New York, N.Y.) Vol. 139; no. 25; pp. e1144 - e1161
• Main Authors: Wilson, Peter W.F., Polonsky, Tamar S., Miedema, Michael D., Khera, Amit, Kosinski, Andrzej S., Kuvin, Jeffrey T.
• Format: Journal Article
• Language: English
• Published: United States by the American College of Cardiology Foundation and the American Heart Association, Inc 18.06.2019
• Subjects: Anticholesteremic Agents - adverse effects; Anticholesteremic Agents - therapeutic use; Biomarkers - blood; Cardiology - standards; Cardiovascular Diseases - blood; Cardiovascular Diseases - diagnosis; Cardiovascular Diseases - epidemiology; Cardiovascular Diseases - prevention & control; Cholesterol - blood; Consensus; Evidence-Based Medicine - standards; Humans; Hyperlipidemias - blood; Hyperlipidemias - diagnosis; Hyperlipidemias - drug therapy; Hyperlipidemias - epidemiology; Randomized Controlled Trials as Topic; Risk Assessment; Risk Factors; Treatment Outcome; cardiovascular disease; patient compliance; risk assessment; lipids; drug therapy; risk reduction discussion; hydroxymethylglutaryl-CoA reductase inhibitors/statins; risk treatment discussion, secondary prevention; proprotein convertase subtilisin/kexin type 9 inhibitor (PCSK9) inhibitors; biomarkers, coronary artery calcium score; diabetes mellitus; hypercholesterolemia; pharmacological; AHA Scientific Statements; Guidelines; cholesterol, LDL-cholesterol; ezetimibe; primary prevention
• ISSN: 0009-7322; 1524-4539; 1524-4539
• DOI: 10.1161/CIR.0000000000000626

BACKGROUND:The 2013 American College of Cardiology/American Heart Association guidelines for the treatment of blood cholesterol found little evidence to support the use of nonstatin lipid-modifying medications to reduce atherosclerotic cardiovascular disease (ASCVD) events. Since publication of thes...