Juvenile-onset Normal Tension Glaucoma From Chronic, Recurrent Low Cerebrospinal Fluid Pressure

• Published in: Journal of glaucoma Vol. 25; no. 8; p. e738
• Main Authors: Yusuf, Imran H, Ratnarajan, Gokularaj, Kerr, Richard S, Salmon, John F
• Format: Journal Article
• Language: English
• Published: United States 01.08.2016
• Subjects: Adult; Cerebrospinal Fluid Pressure - physiology; Chronic Disease; Humans; Intracranial Hypotension - complications; Intracranial Hypotension - physiopathology; Intraocular Pressure - physiology; Low Tension Glaucoma - diagnosis; Low Tension Glaucoma - etiology; Low Tension Glaucoma - physiopathology; Male; Recurrence

The evidence for low cerebrospinal fluid pressure (CSFP) as a key parameter in the pathogenesis of glaucoma is increasing. Primate models have demonstrated the onset normal tension glaucoma (NTG) from experimentally induced chronic intrathecal hypotension; an approach not possible in human subjects....