Strategies to detect abnormal glucose metabolism in people at high risk of cardiovascular disease from the ORIGIN (Outcome Reduction with Initial Glargine Intervention) trial population

• Published in: Journal of diabetes Vol. 3; no. 3; pp. 232 - 237
• Main Authors: BADINGS, Erik A., DYAL, Lyanne, SCHOTERMAN, Lydia, LOK, Dirk J.A., STOEL, Ies, GERDING, Martin N., GERSTEIN, Hertzel C., TIJSSEN, Jan G.P.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.09.2011
• Subjects: Aged; Blood Glucose - metabolism; cardiovascular disease; Cardiovascular Diseases - blood; Cardiovascular Diseases - diagnosis; Cross-Sectional Studies; diabetes mellitus; Diabetes Mellitus, Type 2 - blood; Diabetes Mellitus, Type 2 - diagnosis; Diabetes Mellitus, Type 2 - drug therapy; diagnosis; Fasting - blood; fasting plasma glucose; Female; Glucose Intolerance - blood; Glucose Intolerance - diagnosis; Glucose Tolerance Test; glycated hemoglobin; Glycated Hemoglobin A - metabolism; Humans; Hypoglycemic Agents - therapeutic use; Insulin Glargine; Insulin, Long-Acting - therapeutic use; Male; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Risk Factors; ROC Curve

Background:  To investigate whether the combination of HbA1c and fasting plasma glucose (FPG) can be used for the diagnosis of diabetes and impaired glucose tolerance (IGT) in people at high risk of cardiovascular disease (CVD). Methods:  A cross‐sectional study was performed on 2907 people at high...