Microtubule-associated proteins 1A and LC2. Two proteins encoded in one messenger RNA

• Published in: The Journal of biological chemistry Vol. 267; no. 23; pp. 16561 - 16566
• Main Authors: LANGKOPF, A, HAMMARBACK, J. A, MÜLLER, R, VALLEE, R. B, GARNER, C. C
• Format: Journal Article
• Language: English
• Published: Bethesda, MD American Society for Biochemistry and Molecular Biology 15.08.1992
• Subjects: Amino Acid Sequence; Animals; Base Sequence; Biological and medical sciences; Blotting, Northern; Brain - physiology; Cattle; cDNA; Cloning, Molecular; DNA Probes; Fundamental and applied biological sciences. Psychology; Gene Library; genes; Genes. Genome; Macromolecular Substances; microtubule-associated protein 1A; microtubule-associated protein LC2; Microtubule-Associated Proteins - genetics; Molecular and cellular biology; Molecular genetics; Molecular Sequence Data; nucleotide sequence; Oligodeoxyribonucleotides; Polymerase Chain Reaction - methods; predictions; Rats; Restriction Mapping; RNA - genetics; RNA - isolation & purification; RNA, Messenger - genetics; RNA, Messenger - metabolism; Sequence Homology, Nucleic Acid; Northern blotting; Vertebrata; Mammalia; Complementary DNA; Rat; Rodentia; Primary structure; Microtubule associated protein; Gene expression; Brain (vertebrata); Immunological method

The deduced amino acid sequence for the filamentous microtubule-associated protein (MAP) 1A, thought to be involved in stabilizing the mature neuronal cytoskeleton, has been determined from a series of overlapping cDNA clones. Though previously described as biochemically and immunologically distinct...