Expansion sequencing: Spatially precise in situ transcriptomics in intact biological systems - Alon, Shahar; Goodwin, Daniel R.; Sinha, Anubhav; Wassie, Asmamaw T.; Chen, Fei; Daugharthy, Evan R.; Bando, Yosuke; Kajita, Atsushi; Xue, Andrew G.; Marrett, Karl; Prior, Robert; Cui, Yi; et al. (Science (American Association for the Advancement of Science), 2021)
Keywords: Alternative splicing; Animals; Biopsy; Breast cancer; Breast Neoplasms - immunology; Breast Neoplasms - pathology; Cancer; Chemical reactions; Compartments; Context; Dendrites; Dendritic Spines; Dendritic transport; Female; Fluorescence; Gene expression; Gene Expression Profiling - methods; Gene mapping; Gene sequencing; Genes; Hippocampus; Humans; Hydrogels; Immune system; Interrogation; Introns; Localization; Mapping; Medical imaging; Metastases; Metastasis; Mice; Microscopes; Microscopy; Molecular Imaging - methods; Multiplexing; Neuroimaging; Neurons; Polymers; Pyramidal cells; Ribonucleic acid; RNA; Sequence Analysis, RNA - methods; Single-Cell Analysis - methods; Spatial discrimination; Spatial resolution; Tissues; Transcription factors; Transcripts (Written Records); Tumor cells; Tumors; Visual Cortex; Visual observation; Visualization