Decidual relaxins: Gene and protein up-regulation in preterm premature rupture of the membranes by complementary DNA arrays and quantitative immunocytochemistry

• Published in: American journal of obstetrics and gynecology Vol. 187; no. 3; pp. 785 - 797
• Main Authors: Tashima, Lily S., Yamamoto, Sandra Y., Yasuda, Maaya, Millar, Lynnae K., Bryant-Greenwood, Gillian D.
• Format: Journal Article
• Language: English
• Published: Philadelphia, PA Mosby, Inc 01.09.2002; Elsevier
• Subjects: Apoptosis; Biological and medical sciences; decidua; Decidua - chemistry; Decidua - metabolism; Densitometry; Diseases of mother, fetus and pregnancy; Female; fetal membranes; Fetal Membranes, Premature Rupture - metabolism; Gene Expression Regulation; Gynecology. Andrology. Obstetrics; Humans; Immunohistochemistry; Medical sciences; Metalloendopeptidases - genetics; Oligonucleotide Array Sequence Analysis; Pregnancy; Pregnancy. Fetus. Placenta; preterm rupture; Relaxin; Relaxin - analysis; Relaxin - genetics; Up-Regulation; preterm rupture; decidua; fetal membranes; Relaxin; Human; Biochemical analysis; Pregnancy disorders; Immunocytochemistry; Pathogenesis; DNA chip; Premature rupture of membrane; Decidua; Ovarian hormone; Pathology; Protein hormone; Delivery disorders; Female; Molecular biology; Fetoplacental membrane

Objective: This study was undertaken to show both decidual relaxin gene and protein up-regulation in preterm premature rupture of the fetal membranes. Study Design: Membranes after preterm premature rupture (n = 4) have been matched in pairs with preterm intact membranes (n = 4). These tissues were...