Nicotinic Acetylcholine Receptor Subunit Alpha-5 Promotes Radioresistance via Recruiting E2F Activity in Oral Squamous Cell Carcinoma

• Published in: Journal of clinical medicine Vol. 8; no. 9; p. 1454
• Main Authors: Lin, Che-Hsuan, Lee, Hsun-Hua, Kuei, Chia-Hao, Lin, Hui-Yu, Lu, Long-Sheng, Lee, Fei-Peng, Chang, Jungshan, Wang, Jia-Yi, Hsu, Kai-Cheng, Lin, Yuan-Feng
• Format: Journal Article
• Language: English
• Published: MDPI 12.09.2019

Radiotherapy is commonly used to treat patients with oral squamous cell carcinoma (OSCC), but a subpopulation of OSCC patients shows a poor response to irradiation treatment. Therefore, identifying a biomarker to predict the effectiveness of radiotherapy in OSCC patients is urgently needed. In silic...