Self-assembly, interfacial properties, interactions with macromolecules and molecular modelling and simulation of microbial bio-based amphiphiles (biosurfactants). A tutorial review
Chemical surfactants are omnipresent in consumer products, but they are the subject of environmental concerns. For this reason, the complete replacement of petrochemical surfactants by biosurfactants constitutes a holy grail, but this is far from possible in the near future. Although the "biosu...
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| Published in | Green chemistry : an international journal and green chemistry resource : GC Vol. 23; no. 11; pp. 3842 - 3944 |
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| Main Authors | , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Cambridge
Royal Society of Chemistry
09.06.2021
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| Subjects | |
| Online Access | Get full text |
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| Summary: | Chemical surfactants are omnipresent in consumer products, but they are the subject of environmental concerns. For this reason, the complete replacement of petrochemical surfactants by biosurfactants constitutes a holy grail, but this is far from possible in the near future. Although the "biosurfactants revolution" has not yet occurred, mainly due to the higher cost and lower availability of biosurfactants, another reason could explain this fact: poor knowledge of their properties in solution. This tutorial review aims to review the self-assembly properties and phase behavior, experimentally (sections 3.3 and 3.4) and through molecular modelling (section 6), in water of the most important microbial biosurfactants (sophorolipids, rhamnolipids, surfactin, cellobiose lipids, glucolipids) as well as their major derivatives. A critical discussion of such properties in light of the well-known packing parameter of surfactants is also provided (section 3.5). The relationship between the nanoscale self-assembly and macroscopic material's properties, including hydrogelling, solid foaming, templating or encapsulation, is specifically discussed (section 3.7). We also present their self-assembly and adsorption at flat and complex air/liquid (
e.g.
, foams), air/solid (adhesion), liquid/solid (nanoparticles) and liquid/liquid (
e.g.
, emulsions) interfaces (section 4). A critical discussion on the use of biosurfactants as capping agents for the development of stable nanoparticles is specifically provided (section 4.2.4). Finally, we discuss the major findings involving biosurfactants and macromolecules, including proteins, enzymes, polymers and polyelectrolytes.
Amphiphiles obtained by microbial fermentation, known as biosurfactants or bioamphiphiles, are reviewed in terms of their solution experimental and theoretical self-assembly properties, interface properties and interactions with macromolecules. |
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| Bibliography: | Niki Baccile is a physicochemist working in the field of materials' science. He obtained his PhD in Materials Chemistry in 2006 at the Laboratoire de Chimie de la Matière Condensée de Paris (LCMCP), Université Pierre et Marie Curie (now Sorbonne Université), Paris (France), and worked as a post-doc at the Institut Charles Gerhardt in Montpellier (France) in 2007 and at the Max Planck Institute of Colloids and Interfaces, Potsdam-Golm (Germany), in 2008. Since 2008, he has been a full-time CNRS research fellow at the LCMCP, Sorbonne Université, Paris. He currently explores the self-organization of microbial biosurfactants (sophorolipids, glucolipids, cellobiose lipids) and their potential use in materials science. Silvia Alonso-de Castro obtained her BSc (2011) and MSc in Applied Chemistry and Pharmacology (2013) at the University Jaume I (Spain). In 2018, she finished her PhD in the Inorganic Photochemistry lab of Prof. Salassa. Her PhD research was focused on the photocatalytic activation of metal based anticancer prodrug candidates, by employing flavins and flavoproteins as catalysts. Then, in 2019, she joined the LCMCP at Sorbonne Université (France) as a postdoctoral researcher, where she studied the role of biosurfactants in the synthesis of inorganic nanoparticles and the viability of multilamellar wall vesicles as drug delivery systems. Stéphane Abel is a full researcher in molecular modelling and simulation at the French Alternative Energies and Atomic Energy Commission (CEA) and the Institute for Integrative Biology of the Cell (I2BC) of the Paris Saclay University. He received his PhD degree in molecular simulation in 2007 from the University of Pierre and Marie Curie (now Sorbonne Université), Paris (France). His current work focuses on employing molecular simulation techniques to study surfactant assemblies and lipid membranes, in particular, to evaluate and tailor them for specific applications in the membrane protein and environmental fields. Chloé Seyrig is a French PhD student. After a bachelor in biomedical sciences (Paris V), she obtained a master in Biomedical Engineering, with a specialty in Biomaterials (Paris V). She is currently preparing her PhD thesis on stimuli-responsive biosurfactant-biopolymer self-assembled structures at the Laboratoire de Chimie de la Matière Condensée de Paris (Sorbonne Université, Paris, France). Starmerella bombicola Alexandre Poirier has had a Post-Doctoral contract with the SMILES team of the Laboratoire de Chimie de la Matière Condensée de Paris, France, since 2020. His PhD thesis research was achieved in 2019 at the Laboratoire Charles Coulomb, France. He is developing his skills around bio-based compounds with a physical-chemistry approach. His PhD and Post-doc research are dedicated to the understanding of mechanisms allowing thickening of an aqueous composition, by the interfacial behavior of an industrial protein extract (PhD thesis) and by the self-assembly of a biosurfactant. for the production of a portfolio of novel glycolipid biosurfactants. She subsequently embarked on the quest to develop sustainable, scalable and efficient production processes (fermentation and purification) for these novel compounds. Dr ir. Sophie Roelants is Innovation Manager Biosurfactants and has worked on microbial biosurfactants for over 12 years. She managed(s)/coordinated several projects on the development of microbial strains, fermentation- and purification processes and application research for (new-to-nature) biosurfactants. She holds a degree in Bio Science Engineering (Ghent University, 2007) and a PhD in Applied Biological Sciences (Ghent University, 2013). Sophie and her team have developed a battery of yeast strains derived from the non-conventional yeast ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 |
| ISSN: | 1463-9262 1463-9270 1463-9270 |
| DOI: | 10.1039/d1gc00097g |