Dopamine transporter regulates the enhancement of novelty processing by a negative emotional context

• Published in: Neuropsychologia Vol. 48; no. 5; pp. 1483 - 1488
• Main Authors: Garcia-Garcia, Manuel, Clemente, Immaculada, Domínguez-Borràs, Judith, Escera, Carles
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ltd 01.04.2010; Elsevier
• Subjects: Adolescent; Adult; Affect; Auditory Perception; Behavioral psychophysiology; Biological and medical sciences; Distraction; DNA Primers - genetics; Dopamine; Dopamine Plasma Membrane Transport Proteins - genetics; Emotional context; Emotional modulation; Female; Fundamental and applied biological sciences. Psychology; Humans; Male; Neurotransmission and behavior; Novelty-P3; Psychology. Psychoanalysis. Psychiatry; Psychology. Psychophysiology; SLC6A3/DAT1; Social Environment; Young Adult; Distraction; Emotional context; Dopamine; Emotional modulation; SLC6A3/DAT1; Novelty-P3; Context; Human; Affect affectivity; Attention; Cognition; Emotion emotionality; Catecholamine; Modulation; Neurotransmitter; Carrier protein; Novelty

The dopaminergic (DA) system has been recently related the emotional modulation of cognitive processes. Moreover, patients with midbrain DA depletion, such as Parkinson's Disease (PD), have shown diminished reactivity during unpleasant events. Here, we examined the role of DA in the enhancement...