Association of the invasion ability of Porphyromonas gingivalis with the severity of periodontitis

• Published in: Virulence Vol. 6; no. 3; pp. 274 - 281
• Main Authors: Baek, Keum Jin, Ji, Suk, Kim, Yong Chul, Choi, Youngnim
• Format: Journal Article
• Language: English
• Published: United States Taylor & Francis 03.04.2015
• Subjects: Adhesins, Bacterial - metabolism; Adult; Amino Acid Sequence; cytokine proteolytic activity; Cytokines - immunology; Cytokines - metabolism; Female; Fimbriae Proteins - chemistry; Fimbriae Proteins - genetics; Fimbriae Proteins - metabolism; Flow Cytometry; Humans; invasion ability; Male; Middle Aged; Mutation; periodontitis; Periodontitis - immunology; Periodontitis - microbiology; Phylogeny; Porphyromonas gingivalis; Porphyromonas gingivalis - classification; Porphyromonas gingivalis - isolation & purification; Porphyromonas gingivalis - metabolism; Porphyromonas gingivalis - pathogenicity; Proteolysis; Research Paper; Sequence Analysis, DNA; severity; Porphyromonas gingivalis; severity; invasion ability; cytokine proteolytic activity; periodontitis
• ISSN: 2150-5594; 2150-5608; 2150-5608
• DOI: 10.1080/21505594.2014.1000764

Porphyromonas gingivalis is one of the well-characterized periodontal pathogens involved in periodontitis. The invasive and proteolytic activities of P. gingivalis clinical isolates have been shown to be associated with heterogenic virulence, as determined in a mouse abscess model. The aims of the p...