Using Expanded Natural Killer Cells as Therapy for Invasive Aspergillosis

• Published in: Journal of fungi (Basel) Vol. 6; no. 4; p. 231
• Main Authors: Soe, Win Mar, Lim, Joan Hui Juan, Williams, David L., Goh, Jessamine Geraldine, Tan, Zhaohong, Sam, Qi Hui, Chotirmall, Sanjay H., Ali, Nur A’tikah Binte Mohamed, Lee, Soo Chin, Seet, Ju Ee, Ravikumar, Sharada, Chai, Louis Yi Ann
• Format: Journal Article
• Language: English
• Published: MDPI 17.10.2020; MDPI AG
• Subjects: antifungal immunity; Aspergillus; expanded natural killer cells; fungal infection; immune evasion; immune recognition

Invasive aspergillosis (IA) is a major opportunistic fungal infection in patients with haematological malignancies. Morbidity and mortality rates are high despite anti-fungal treatment, as the compromised status of immune system prevents the host from responding optimally to conventional therapy. Th...