The cortical neuroanatomy of neuropsychological deficits in mild cognitive impairment and Alzheimer's disease: A surface-based morphometric analysis

• Published in: Neuropsychologia Vol. 49; no. 14; pp. 3931 - 3945
• Main Authors: Ahn, Hyun-Jung, Seo, Sang Won, Chin, Juhee, Suh, Mee Kyung, Lee, Byung Hwa, Kim, Sung Tae, Im, Kiho, Lee, Jong-Min, Lee, Jun Hong, Heilman, Kenneth M., Na, Duk L.
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ltd 01.12.2011; Elsevier
• Subjects: Adult and adolescent clinical studies; Aged; Aged, 80 and over; Alzheimer Disease - complications; Alzheimer Disease - pathology; Alzheimer's disease; Biological and medical sciences; Brain Mapping; Cerebral Cortex - pathology; Cerebral Cortex - physiopathology; Cognition; Cognitive Dysfunction - etiology; Cognitive Dysfunction - pathology; Cortical atrophy; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases; Dissociative Disorders; Female; Functional Laterality; Geriatrics; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Medical sciences; Middle Aged; Mild cognitive impairment; Neurology; Neuropsychological Tests; Organic mental disorders. Neuropsychology; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Statistics as Topic; Cognition; Neuropsychological tests; Mild cognitive impairment; Alzheimer's disease; Cortical atrophy; Human; Nervous system diseases; Cerebral cortex; Cognitive disorder; Alzheimer disease; Central nervous system; Neuropsychological test; Psychometrics; Encephalon; Cerebral disorder; Atrophy; Central nervous system disease; Degenerative disease; mild cognitive impairment; Morphometry

► There are different patterns of cortical thinning associated with neuropsychological tests. ► The neuropsychological tests have a hemispheric laterality associated with each functions. ► The patterns of cortical thinning are pathological markers for cognitive dysfunction. Patients with probable Al...