Responsiveness of sensorimotor cortex during pharmacological intervention with bromazepam

• Published in: Neuroscience letters Vol. 448; no. 1; pp. 33 - 36
• Main Authors: Cunha, Marlo, Portela, Cláudio, Bastos, Victor H., Machado, Dionis, Machado, Sergio, Velasques, Bruna, Budde, Henning, Cagy, Maurício, Basile, Luis, Piedade, Roberto, Ribeiro, Pedro
• Format: Journal Article
• Language: English
• Published: Shannon Elsevier Ireland Ltd 19.12.2008; Elsevier
• Subjects: Adult; Anti-Anxiety Agents - pharmacology; Biological and medical sciences; Bromazepam; Bromazepam - pharmacology; Double-Blind Method; Electroencephalography; Electroencephalography - drug effects; Electroencephalography - methods; Female; Fundamental and applied biological sciences. Psychology; Humans; Male; Maximum Tolerated Dose; Motor Cortex - radiation effects; Motor learning; Neuropsychological Tests; Problem Solving - drug effects; Relative power; Sensorimotor integration; Somatosensory Cortex - radiation effects; Typewriting; Vertebrates: nervous system and sense organs; Young Adult; Bromazepam; Relative power; Sensorimotor integration; Electroencephalography; Motor learning; Typewriting; Sensorimotor coordination; Central nervous system; Electrophysiology; Sensorimotor cortex; Encephalon

The aim of this study was to investigate the influence of bromazepam on EEG and the motor learning process when healthy subjects were submitted to a typewriting task. We investigated bromazepam due to its abuse by various populations and its prevalent clinical use among older individuals which are m...