Endotoxin neutralization by an O-antigen specific monoclonal antibody: A potential novel therapeutic approach against Klebsiella pneumoniae ST258 - Szijártó, Valéria; Guachalla, Luis M.; Hartl, Katharina; Varga, Cecília; Badarau, Adriana; Mirkina, Irina; Visram, Zehra C.; Stulik, Lukas; Power, Christine A.; Nagy, Eszter; Nagy, Gábor (Virulence, 2017)
Keywords: Animals; Antibodies, Bacterial - immunology; Antibodies, Bacterial - therapeutic use; Antibodies, Monoclonal - immunology; Antibodies, Monoclonal - therapeutic use; carbapenem-resistant Klebsiella; endotoxin neutralization; Endotoxins - immunology; Female; Humans; Immunization, Passive; Klebsiella Infections - drug therapy; Klebsiella Infections - immunology; Klebsiella Infections - microbiology; Klebsiella pneumoniae - drug effects; Klebsiella pneumoniae - genetics; Klebsiella pneumoniae - immunology; Klebsiella pneumoniae ST258; Male; Mice; Mice, Inbred BALB C; monoclonal antibody; Neutralization Tests; O Antigens - immunology; protective efficacy; Rabbits; Rats; Rats, Sprague-Dawley; Research Paper; carbapenem-resistant Klebsiella; endotoxin neutralization; protective efficacy; monoclonal antibody; Klebsiella pneumoniae ST258