Anaplastic Thyroid Cancer: Clinical Picture of the Last Two Decades at a Single Oncology Referral Centre and Novel Therapeutic Options

• Published in: Cancers Vol. 11; no. 8; p. 1188
• Main Authors: Simões-Pereira, Joana, Capitão, Ricardo, Limbert, Edward, Leite, Valeriano
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 15.08.2019; MDPI
• Subjects: Cancer therapies; Chemotherapy; Clinical trials; Dysphagia; Dyspnea; Medical prognosis; Metastases; Metastasis; Multivariate analysis; Ostomy; Patients; Protein-tyrosine kinase; Radiation therapy; Surgery; Survival; Thyroid cancer; Tumors; tyrosine kinase inhibitors; anaplastic thyroid cancer; immune checkpoint inhibitors; survival

Anaplastic thyroid cancer (ATC) is a rare tumour but also one of the most lethal malignancies. Therapeutic modalities have usually been limited, but clinical trials with new drugs are now being implemented. The aims of this study were to analyse the clinical presentation, therapeutic modalities and...