Improvement in blood lipid levels by dietary sn-1,3-diacylglycerol in young women with variants of lipid transporters 54T-FABP2 and -493g-MTP

• Published in: Biochem Biophys Res Commun Vol. 302; no. 4; pp. 743 - 750
• Main Authors: Yanagisawa, Yoshiko, Kawabata, Terue, Tanaka, Osamu, Kawakami, Masanobu, Hasegawa, Kyoko, Kagawa, Yasuo
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 21.03.2003; Elsevier BV
• Subjects: Adipose Tissue; Adipose Tissue - anatomy & histology; Adipose Tissue - metabolism; administration & dosage; anatomy & histology; blood; blood lipids; Carrier Proteins; Carrier Proteins - genetics; Carrier Proteins - metabolism; Diacylglycerol; diacylglycerols; dietary fat; Dietary Fats; Diglycerides; Diglycerides - administration & dosage; Double-Blind Method; FABP2; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Female; genetics; Genotype; Humans; Japan; lipid metabolism; Lipids; Lipids - blood; metabolism; MTP; Neoplasm Proteins; SCAP; Serum lipids; SNPs; Tumor Suppressor Proteins; women; young adults; Japan; Serum lipids; SNPs; MTP; FABP2; SCAP; Diacylglycerol

In a double-blind parallel-group study, serum lipids and visceral fat/total fat ratio in young women ( n=49) with variants of lipid transporters, i.e., fatty acid binding protein 2 (FABP2) and microsomal triglyceride transfer protein (MTP), were analyzed by substituting dietary triacylglycerol (TAG)...