Seizure Associated with Use of Visicol for Colonoscopy
To the Editor: Visicol has been prescribed more than 210,000 times since its introduction last year. The letter by Mackey et al. (June 27 issue) 1 describes four patients with seizures after the use of Visicol for colonic cleansing and suggests that the risk of seizures may be greater with this prod...
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| Published in | The New England journal of medicine Vol. 347; no. 4; pp. 295 - 296 |
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| Main Authors | , |
| Format | Journal Article |
| Language | English |
| Published |
United States
Massachusetts Medical Society
25.07.2002
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| Subjects | |
| Online Access | Get full text |
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| Abstract | To the Editor:
Visicol has been prescribed more than 210,000 times since its introduction last year. The letter by Mackey et al. (June 27 issue)
1
describes four patients with seizures after the use of Visicol for colonic cleansing and suggests that the risk of seizures may be greater with this product than with other purgatives. We take issue with this suggestion.
All four patients discussed by Mackey et al. had severe hyponatremia, which was the most likely cause of their seizures. Hyponatremia could have resulted from sodium losses through gastrointestinal mechanisms or sweating, excessive free-water ingestion, and excessive secretion of . . . |
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| AbstractList | To the Editor:
Visicol has been prescribed more than 210,000 times since its introduction last year. The letter by Mackey et al. (June 27 issue)
1
describes four patients with seizures after the use of Visicol for colonic cleansing and suggests that the risk of seizures may be greater with this product than with other purgatives. We take issue with this suggestion.
All four patients discussed by Mackey et al. had severe hyponatremia, which was the most likely cause of their seizures. Hyponatremia could have resulted from sodium losses through gastrointestinal mechanisms or sweating, excessive free-water ingestion, and excessive secretion of . . . |
| Author | Rose, Martin Jacob, Leonard S |
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| Cites_doi | 10.1016/S0140-6736(00)03619-9 10.1046/j.1365-2036.2002.01259.x 10.1067/mge.2001.113274 10.1056/NEJM200206273462619 |
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| Snippet | To the Editor:
Visicol has been prescribed more than 210,000 times since its introduction last year. The letter by Mackey et al. (June 27 issue)
1
describes... |
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| SubjectTerms | Cathartics - adverse effects Colonoscopy Humans Hyponatremia - chemically induced Hyponatremia - complications Phosphates - adverse effects Polyethylene Glycols - adverse effects Seizures - etiology Vasopressins - blood |
| Title | Seizure Associated with Use of Visicol for Colonoscopy |
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