Bacterial membrane vesicles: Biogenesis, immune regulation and pathogenesis

• Published in: Cellular microbiology Vol. 18; no. 11; pp. 1518 - 1524
• Main Authors: Pathirana, Rishi D., Kaparakis‐Liaskos, Maria
• Format: Journal Article
• Language: English
• Published: England Hindawi Limited 01.11.2016
• Subjects: Adaptive Immunity; Animals; Bacteria; Cell-Derived Microparticles - physiology; Epithelial Cells - microbiology; Gram-Negative Bacteria - immunology; Gram-Negative Bacteria - physiology; Gram-Negative Bacterial Infections - microbiology; Host-Pathogen Interactions; Humans; Immunity, Innate

Outer membrane vesicles were first described approximately 50 years ago and for many years were considered to be an artifact of bacterial growth. Since that initial discovery, it has become evident that outer membrane vesicles are produced by almost all Gram‐negative bacteria as part of their normal...