Phenol Ugi-Smiles Systems: Strategies for the Multicomponent N-Arylation of Primary Amines with Isocyanides, Aldehydes, and Phenols
A Smiles rearrangement is the key step in the efficient coupling of primary amines with isocyanides, carbonyl compounds, and electron‐deficient substituted phenols to form N‐aryl amines (see picture). The presence of a nitro or ester group on the resulting adduct allows applications in heterocyclic...
Saved in:
Published in | Angewandte Chemie (International ed.) Vol. 44; no. 48; pp. 7961 - 7964 |
---|---|
Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
Weinheim
WILEY-VCH Verlag
09.12.2005
WILEY‐VCH Verlag Wiley |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Be the first to leave a comment!