Intravenous Injection of Apolipoprotein A-V Reconstituted High-Density Lipoprotein Decreases Hypertriglyceridemia in apoav−/− Mice and Requires Glycosylphosphatidylinositol-Anchored High-Density Lipoprotein–Binding Protein 1 - Shu, Xiao; Nelbach, Lisa; Weinstein, Michael M.; Burgess, Braydon L.; Beckstead, Jennifer A.; Young, Stephen G.; Ryan, Robert O.; Forte, Trudy M. (Arteriosclerosis, thrombosis, and vascular biology, 2010)
Keywords: Animals; Apolipoprotein A-V; Apolipoproteins - deficiency; Apolipoproteins - genetics; Apolipoproteins A - administration & dosage; Apolipoproteins A - blood; Atherosclerosis (general aspects, experimental research); Binding Sites; Biological and medical sciences; Biomarkers - blood; Blood and lymphatic vessels; Blood coagulation. Blood cells; Cardiology. Vascular system; Disease Models, Animal; Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous; Dose-Response Relationship, Drug; Down-Regulation; Fundamental and applied biological sciences. Psychology; Heparin - administration & dosage; Heparin - metabolism; Humans; Hypertriglyceridemia - drug therapy; Hypertriglyceridemia - genetics; Hypertriglyceridemia - metabolism; Hypolipidemic Agents - administration & dosage; Hypolipidemic Agents - blood; Injections, Intravenous; Lipoproteins, HDL - administration & dosage; Lipoproteins, HDL - blood; Lipoproteins, VLDL - blood; Male; Medical sciences; Mice; Mice, Knockout; Molecular and cellular biology; Mutagenesis, Site-Directed; Mutation; Platelet; Receptors, Lipoprotein - genetics; Receptors, Lipoprotein - metabolism; Recombinant Proteins - administration & dosage; Time Factors; Triglycerides - blood; apolipoproteins; Intravenous administration; Rodentia; Metabolic diseases; Lipids; Cardiovascular disease; Hyperlipoproteinemia; Lipoprotein; Triglyceride; Enzymopathy; Vascular disease; Apolipoprotein A; Binding protein; Vertebrata; Mammalia; Mouse; Hypertriglyceridemia; Animal; Atherosclerosis; Dyslipemia; lipoproteins