Gene–Gene Interactions Among PRKCA, NOS3 and BDKRB2 Polymorphisms Affect the Antihypertensive Effects of Enalapril - Oliveira‐Paula, Gustavo H.; Luizon, Marcelo R.; Lacchini, Riccardo; Fontana, Vanessa; Silva, Pamela S.; Biagi, Celso; Tanus‐Santos, Jose E. (Basic & clinical pharmacology & toxicology, 2017)
Keywords: Adult; Angiotensin; Angiotensin-Converting Enzyme Inhibitors - pharmacology; Angiotensin-Converting Enzyme Inhibitors - therapeutic use; Antihypertensive Agents - pharmacology; Antihypertensive Agents - therapeutic use; Antihypertensives; Blood pressure; Blood Pressure - drug effects; Bradykinin; Enalapril - pharmacology; Enalapril - therapeutic use; Enzyme inhibitors; Epistasis, Genetic; Female; Gene polymorphism; Genotype; Genotypes; Haplotypes; Humans; Hypertension - drug therapy; Kinases; Male; Middle Aged; Nitric oxide; Nitric Oxide Synthase Type III - genetics; Nitric Oxide Synthase Type III - metabolism; Nitric-oxide synthase; NOS3 protein; Pharmacogenomic Variants; Polymorphism; Polymorphism, Single Nucleotide; Protein kinase C; Protein Kinase C-alpha - genetics; Protein Kinase C-alpha - metabolism; Proteins; Receptor, Bradykinin B2 - genetics; Receptor, Bradykinin B2 - metabolism; Signal Transduction