Effect of brain‐derived neurotrophic factor on sperm function, oxidative stress and membrane integrity in human

• Published in: Andrologia Vol. 49; no. 2; pp. e12601 - n/a
• Main Authors: Najafi, A., Amidi, F., Sedighi Gilani, M. A., Moawad, A. R., Asadi, E., Khanlarkhni, N., Fallah, P., Rezaiian, Z., Sobhani, A.
• Format: Journal Article
• Language: English
• Published: Germany Wiley Subscription Services, Inc 01.03.2017
• Subjects: Adult; Apoptosis - drug effects; Apoptotic‐like changes; BDNF; Brain-Derived Neurotrophic Factor - pharmacology; Cell Membrane - drug effects; Healthy Volunteers; Humans; Iran; Male; Oxidative Stress - drug effects; Reactive Oxygen Species - metabolism; ROS; Sperm Motility - drug effects; sperm preparation; Spermatozoa - drug effects; Spermatozoa - physiology; Young Adult; sperm preparation; Apoptotic-like changes; BDNF; ROS

Summary Oxidative stress has negative impacts on the clinical outcomes of assisted reproduction techniques. The brain‐derived neurotrophic factor (BDNF) promotes the viability of nerve cells and is known to decrease oxidative stress and apoptosis in different cells. The aim of this study was to eval...